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LINK . SPRINGER . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Link.springer.com Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
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We are analyzing https://link.springer.com/article/10.1007/s00424-014-1578-z.

Title:
Piezo channels: from structure to function | Pflügers Archiv - European Journal of Physiology
Description:
Mechanotransduction is the conversion of mechanical stimuli into biological signals. It is involved in the modulation of diverse cellular functions such as migration, proliferation, differentiation, and apoptosis as well as in the detection of sensory stimuli such as air vibration and mechanical contact. Therefore, mechanotransduction is crucial for organ development and homeostasis and plays a direct role in hearing, touch, proprioception, and pain. Multiple molecular players involved in mechanotransduction have been identified in the past, among them ion channels directly activated by cell membrane deformation. Most of these channels have well-established roles in lower organisms but are not conserved in mammals or fail to encode mechanically activated channels in mammals due to non-conservation of mechanotransduction property. A family of mechanically activated channels that counts only two members in human, piezo1 and 2, has emerged recently. Given the lack of valid mechanically activated channel candidates in mammals in the past decades, particular attention is given to piezo channels and their potential roles in various biological functions. This review summarizes our current knowledge on these ion channels.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

  • Education
  • Science
  • Telecommunications

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
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How Does Link.springer.com Make Money? {💸}

We're unsure if the website is profiting.

The purpose of some websites isn't monetary gain; they're meant to inform, educate, or foster collaboration. Everyone has unique reasons for building websites. This could be an example. Link.springer.com might be earning cash quietly, but we haven't detected the monetization method.

Keywords {🔍}

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Topics {✒️}

post-radiotherapy-induced thyroid tumors yasmine mechioukhi & bertrand coste piezo1-dependent stretch-activated channels month download article/chapter stretch-activated ion channels mechano-gated ion channels stretch-inactivated ion channels reduced integrin-dependent mode limiting anchorage-independent growth vglut3-expressing c-mechanoreceptors drive abeta-afferent impulses epac1-dependent mechanical allodynia mechanosensitive ion channels mechanically activated channels sensory transduction group full article pdf stretch-activated channels related subjects mammalian sensory neurons mechanosensitive channel piezo1 author information authors european economic area privacy choices/manage cookies mechanotransduction protein piezo1 corneal afferent neurons article volkers merkel-cell mechanotransduction lipid bilayer binding dig dis sci 59 bertrand coste mechanosensitive channels ion channels cultured mesangial cells merkel cells transduce epidermal merkel cells cell membrane deformation urothelial cell cultures multiple clinical forms cell calcium 48 pore-forming subunits chronically hypoxic rats stomatin-domain proteins hamill op rapid step perturbation r-ras targeting journal finder publish encode tactile stimuli article log conditions privacy policy piezo channels

Questions {❓}

  • Posokhov YO et al (2007) Is lipid bilayer binding a common property of inhibitor cysteine knot ion-channel blockers?

Schema {🗺️}

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         headline:Piezo channels: from structure to function
         description:Mechanotransduction is the conversion of mechanical stimuli into biological signals. It is involved in the modulation of diverse cellular functions such as migration, proliferation, differentiation, and apoptosis as well as in the detection of sensory stimuli such as air vibration and mechanical contact. Therefore, mechanotransduction is crucial for organ development and homeostasis and plays a direct role in hearing, touch, proprioception, and pain. Multiple molecular players involved in mechanotransduction have been identified in the past, among them ion channels directly activated by cell membrane deformation. Most of these channels have well-established roles in lower organisms but are not conserved in mammals or fail to encode mechanically activated channels in mammals due to non-conservation of mechanotransduction property. A family of mechanically activated channels that counts only two members in human, piezo1 and 2, has emerged recently. Given the lack of valid mechanically activated channel candidates in mammals in the past decades, particular attention is given to piezo channels and their potential roles in various biological functions. This review summarizes our current knowledge on these ion channels.
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         dateModified:2014-07-20T00:00:00Z
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            Neurosciences
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      description:Mechanotransduction is the conversion of mechanical stimuli into biological signals. It is involved in the modulation of diverse cellular functions such as migration, proliferation, differentiation, and apoptosis as well as in the detection of sensory stimuli such as air vibration and mechanical contact. Therefore, mechanotransduction is crucial for organ development and homeostasis and plays a direct role in hearing, touch, proprioception, and pain. Multiple molecular players involved in mechanotransduction have been identified in the past, among them ion channels directly activated by cell membrane deformation. Most of these channels have well-established roles in lower organisms but are not conserved in mammals or fail to encode mechanically activated channels in mammals due to non-conservation of mechanotransduction property. A family of mechanically activated channels that counts only two members in human, piezo1 and 2, has emerged recently. Given the lack of valid mechanically activated channel candidates in mammals in the past decades, particular attention is given to piezo channels and their potential roles in various biological functions. This review summarizes our current knowledge on these ion channels.
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         Pain
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         Molecular Medicine
         Neurosciences
         Cell Biology
         Receptors
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External Links {🔗}(169)

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