We are analyzing https://link.springer.com/article/10.1007/s004010051093.

Title:
Neutrophil infiltration into human gliomas | Acta Neuropathologica
Description:
Human gliomas were analysed for the infiltration of neutrophils using immunohistochemistry by staining sections for CD15-positive and myeloperoxidase-positive cells. Over 70% of all glioma samples analysed (n = 105) had significant neutrophil infiltration, but there was a marked and significant correlation between tumour grade and the extent of the neutrophil infiltration. In the low grade tumours only 40–50% had significant infiltration, while in glioblastoma multiforme over 85% of the samples analysed had significant infiltration. Numbers of neutrophils infiltrating glioblastoma multiforme tumours were also greater than in the other tumour groups. Circulating white blood cell counts were elevated above the normal range in all glioma patients, but this elevation was entirely due to increased numbers of circulating neutrophils. Again, the highest numbers of circulating neutrophils were seen in the glioblastoma multiforme patients. These experiments indicate that glioma-derived factors may directly or indirectly affect the number of circulating neutrophils and influence their infiltration into the tumours.
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Keywords {🔍}

article, infiltration, neutrophil, neutrophils, glioblastoma, privacy, cookies, content, access, information, publish, search, significant, tumour, circulating, data, log, journal, research, acta, human, gliomas, september, fossati, ricevuti, edwards, analysed, glioma, grade, tumours, multiforme, numbers, patients, discover, liverpool, springer, optional, personal, parties, policy, find, track, neuropathologica, cite, gianluca, giovanni, carol, walker, alison, dalton,

Topics {✒️}

month download article/chapter tumour grade privacy choices/manage cookies full article pdf glioblastoma multiforme patients low grade tumours glioma-derived factors pre-treatment neutrophil tumour groups significant neutrophil infiltration t-cell infiltration european economic area glioblastoma multiforme predicts clinical outcome related subjects alison dalton & marco glioma samples analysed conditions privacy policy myeloperoxidase-positive cells life sciences building accepting optional cookies article fossati carol walker check access instant access uk e-mail main content log neutrophil infiltration journal finder publish human gliomas acta neuropathol 98 circulating neutrophils article log september 1999 volume 98 glioma patients article cite privacy policy personal data significant infiltration rossi department books a cell responses information optional cookies manage preferences data protection essential cookies cookies skip subscription content similar content

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         headline:Neutrophil infiltration into human gliomas
         description: Human gliomas were analysed for the infiltration of neutrophils using immunohistochemistry by staining sections for CD15-positive and myeloperoxidase-positive cells. Over 70% of all glioma samples analysed (n = 105) had significant neutrophil infiltration, but there was a marked and significant correlation between tumour grade and the extent of the neutrophil infiltration. In the low grade tumours only 40–50% had significant infiltration, while in glioblastoma multiforme over 85% of the samples analysed had significant infiltration. Numbers of neutrophils infiltrating glioblastoma multiforme tumours were also greater than in the other tumour groups. Circulating white blood cell counts were elevated above the normal range in all glioma patients, but this elevation was entirely due to increased numbers of circulating neutrophils. Again, the highest numbers of circulating neutrophils were seen in the glioblastoma multiforme patients. These experiments indicate that glioma-derived factors may directly or indirectly affect the number of circulating neutrophils and influence their infiltration into the tumours.
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      headline:Neutrophil infiltration into human gliomas
      description: Human gliomas were analysed for the infiltration of neutrophils using immunohistochemistry by staining sections for CD15-positive and myeloperoxidase-positive cells. Over 70% of all glioma samples analysed (n = 105) had significant neutrophil infiltration, but there was a marked and significant correlation between tumour grade and the extent of the neutrophil infiltration. In the low grade tumours only 40–50% had significant infiltration, while in glioblastoma multiforme over 85% of the samples analysed had significant infiltration. Numbers of neutrophils infiltrating glioblastoma multiforme tumours were also greater than in the other tumour groups. Circulating white blood cell counts were elevated above the normal range in all glioma patients, but this elevation was entirely due to increased numbers of circulating neutrophils. Again, the highest numbers of circulating neutrophils were seen in the glioblastoma multiforme patients. These experiments indicate that glioma-derived factors may directly or indirectly affect the number of circulating neutrophils and influence their infiltration into the tumours.
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