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Title:
Alzheimerās disease: transiently developing dendritic changes in pyramidal cells of sector CA1 of the Ammonās horn | Acta Neuropathologica
Description:
In the course of Alzheimerās disease, specific CA1 pyramidal cells develop dendritic changes, which can only be observed transiently. Distal segments of the apical dendrite running through the stratum lacunosum-moleculare show spindle-shaped dilations filled with abnormal tau protein. The alteration eventually leads to amputation of the changed segment. The damage first appears at stage II in the evolution of the neurofibrillary changes [5], is best developed at stage III, and vanishes from the tissue at stage IV. It is usually not observed in stages V and VI (fully developed Alzheimerās disease).
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Keywords {š}
article, alzheimers, disease, braak, privacy, cookies, content, access, information, publish, research, search, dendritic, cells, data, log, journal, acta, transiently, pyramidal, ammons, horn, stage, discover, springer, optional, personal, parties, policy, find, track, neuropathologica, developing, sector, cite, explore, observed, abnormal, tau, protein, evolution, neurofibrillary, developed, institution, basic, open, related, subjects, neuronal, author,
Topics {āļø}
month download article/chapter privacy choices/manage cookies related subjects full article pdf abnormal tau protein transiently developing dendritic european economic area scope submit manuscript apical dendrite running alteration eventually leads conditions privacy policy d-60590 frankfurt/main accepting optional cookies basic research main content log fully developed alzheimer journal finder publish horn access acta neuropathol 93 article braak dendritic cells check access instant access pyramidal cells article log article cite privacy policy personal data books a sector ca1 optional cookies manage preferences data protection essential cookies cookies skip subscription content similar content uni-frankfurt disease neurofibrillary institution subscribe journal publish information observed transiently usage analysis social media varying standards march 1997 volumeĀ 93 distal segments changed segment stage ii
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headline:Alzheimerās disease: transiently developing dendritic changes in pyramidal cells of sector CA1 of the Ammonās horn
description: In the course of Alzheimerās disease, specific CA1 pyramidal cells develop dendritic changes, which can only be observed transiently. Distal segments of the apical dendrite running through the stratum lacunosum-moleculare show spindle-shaped dilations filled with abnormal tau protein. The alteration eventually leads to amputation of the changed segment. The damage first appears at stage II in the evolution of the neurofibrillary changes [5], is best developed at stage III, and vanishes from the tissue at stage IV. It is usually not observed in stages V and VI (fully developed Alzheimerās disease).
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Key words Alzheimerās disease
Neurofibrillary
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Abnormal tau protein
Ammonās horn
Pathology
Neurosciences
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description: In the course of Alzheimerās disease, specific CA1 pyramidal cells develop dendritic changes, which can only be observed transiently. Distal segments of the apical dendrite running through the stratum lacunosum-moleculare show spindle-shaped dilations filled with abnormal tau protein. The alteration eventually leads to amputation of the changed segment. The damage first appears at stage II in the evolution of the neurofibrillary changes [5], is best developed at stage III, and vanishes from the tissue at stage IV. It is usually not observed in stages V and VI (fully developed Alzheimerās disease).
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