Here's how LINK.SPRINGER.COM makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

LINK . SPRINGER . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Link.springer.com Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. CDN Services

We are analyzing https://link.springer.com/article/10.1007/s00401-013-1154-1.

Title:
Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease | Acta Neuropathologica
Description:
Hippocampal sclerosis of aging (HS-Aging) is a causative factor in a large proportion of elderly dementia cases. The current definition of HS-Aging rests on pathologic criteria: neuronal loss and gliosis in the hippocampal formation that is out of proportion to AD-type pathology. HS-Aging is also strongly associated with TDP-43 pathology. HS-Aging pathology appears to be most prevalent in the oldest-old: autopsy series indicate that 5โ€“30 % of nonagenarians have HS-Aging pathology. Among prior studies, differences in study design have contributed to the study-to-study variability in reported disease prevalence. The presence of HS-Aging pathology correlates with significant cognitive impairment which is often misdiagnosed as AD clinically. The antemortem diagnosis is further confounded by other diseases linked to hippocampal atrophy including frontotemporal lobar degeneration and cerebrovascular pathologies. Recent advances characterizing the neurocognitive profile of HS-Aging patients have begun to provide clues that may help identify living individuals with HS-Aging pathology. Structural brain imaging studies of research subjects followed to autopsy reveal hippocampal atrophy that is substantially greater in people with eventual HS-Aging pathology, compared to those with AD pathology alone. Data are presented from individuals who were followed with neurocognitive and neuroradiologic measurements, followed by neuropathologic evaluation at the University of Kentucky. Finally, we discuss factors that are hypothesized to cause or modify the disease. We conclude that the published literature on HS-Aging provides strong evidence of an important and under-appreciated brain disease of aging. Unfortunately, there is no therapy or preventive strategy currently available.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {๐Ÿ“š}

  • Education
  • Science
  • Health & Fitness

Content Management System {๐Ÿ“}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {๐Ÿ“ˆ}

What is the average monthly size of link.springer.com audience?

๐ŸŒ  Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {๐Ÿ’ธ}

We can't tell how the site generates income.

Earning money isn't the goal of every website; some are designed to offer support or promote social causes. People have different reasons for creating websites. This might be one such reason. Link.springer.com might be cashing in, but we can't detect the method they're using.

Keywords {๐Ÿ”}

google, scholar, pubmed, article, cas, disease, hippocampal, alzheimers, dementia, sclerosis, neuropathol, study, neurol, acta, van, aging, pathology, brain, tdp, alzheimer, nelson, neurology, dickson, smith, clinical, frontotemporal, dois, lee, elderly, cognitive, neuropathology, jicha, trojanowski, schmitt, degeneration, dis, weiner, abner, jellinger, hsaging, atrophy, lobar, neuropathologic, association, schneider, kryscio, bennett, white, davis, markesbery,

Topics {โœ’๏ธ}

month download article/chapter tar-dna binding protein-43 tdp43-mediated neurodegeneration proceedings/ieee international symposium genome-wide analysis reveals honolulu-asia aging study tdp-43 c-terminal fragments cerebrovascular diseaseโ€“practical issues cerebral white-matter hyperintensities brain-wide imaging phenotypes high-morbidity brain disease older japanese-american men late-life motor impairment amyotrophic lateral sclerosis hs-aging pathology appears eventual hs-aging pathology type-dependent oxidative damage post-encephalitic parkinsonism brains community-dwelling older persons full article pdf sanders-brown center hippocampal amyloid-beta tardbp mutations frontal lobe degeneration population-based clinicopathological study nature genetics 44 van deerlin vm privacy choices/manage cookies frontotemporal lobar degeneration postmortem mri study hs-aging pathology correlates thornton-wells ta community-based studies large autopsy cohort sanders-brown building 800 mri atrophy measures japanese-american men post-encephalitic parkinsonism epidemiological human studies common neurodegenerative pathologies van der lijn van der lugt van der zee calcineurin/nfat signaling inflammatory cytokines stimulate welsh-bohmer ka neurofibrillary tangle formation cerebrovascular pathology frontotemporal lobar dementia cerebral grey matter

Questions {โ“}

  • Imhof A, Kovari E, von Gunten A, Gold G, Rivara CB, Herrmann FR, Hof PR, Bouras C, Giannakopoulos P (2007) Morphological substrates of cognitive decline in nonagenarians and centenarians: A new paradigm?

Schema {๐Ÿ—บ๏ธ}

WebPage:
      mainEntity:
         headline:Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease
         description:Hippocampal sclerosis of aging (HS-Aging) is a causative factor in a large proportion of elderly dementia cases. The current definition of HS-Aging rests on pathologic criteria: neuronal loss and gliosis in the hippocampal formation that is out of proportion to AD-type pathology. HS-Aging is also strongly associated with TDP-43 pathology. HS-Aging pathology appears to be most prevalent in the oldest-old: autopsy series indicate that 5โ€“30ย % of nonagenarians have HS-Aging pathology. Among prior studies, differences in study design have contributed to the study-to-study variability in reported disease prevalence. The presence of HS-Aging pathology correlates with significant cognitive impairment which is often misdiagnosed as AD clinically. The antemortem diagnosis is further confounded by other diseases linked to hippocampal atrophy including frontotemporal lobar degeneration and cerebrovascular pathologies. Recent advances characterizing the neurocognitive profile of HS-Aging patients have begun to provide clues that may help identify living individuals with HS-Aging pathology. Structural brain imaging studies of research subjects followed to autopsy reveal hippocampal atrophy that is substantially greater in people with eventual HS-Aging pathology, compared to those with AD pathology alone. Data are presented from individuals who were followed with neurocognitive and neuroradiologic measurements, followed by neuropathologic evaluation at the University of Kentucky. Finally, we discuss factors that are hypothesized to cause or modify the disease. We conclude that the published literature on HS-Aging provides strong evidence of an important and under-appreciated brain disease of aging. Unfortunately, there is no therapy or preventive strategy currently available.
         datePublished:2013-07-18T00:00:00Z
         dateModified:2013-07-18T00:00:00Z
         pageStart:161
         pageEnd:177
         sameAs:https://doi.org/10.1007/s00401-013-1154-1
         keywords:
            TDP43
            TDP-43
            TARDBP
            Dementia
            Aging
            Neuropathology
            FTLD
            Epidemiology
            Genetics
            Cognition
            Neuroradiology
            MRI
            Hippocampus
            Pathology
            Arteriolosclerosis
            Cerebrovascular
            Oldest-old
            Neurosciences
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig3_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig4_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig5_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig6_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig7_HTML.jpg
         isPartOf:
            name:Acta Neuropathologica
            issn:
               1432-0533
               0001-6322
            volumeNumber:126
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer Berlin Heidelberg
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Peter T. Nelson
               affiliation:
                     name:University of Kentucky
                     address:
                        name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
                     name:Sanders-Brown Center on Aging, University of Kentucky
                     address:
                        name:Division of Neuropathology, Department of Pathology, Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Charles D. Smith
               affiliation:
                     name:University of Kentucky
                     address:
                        name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
                     name:University of Kentucky
                     address:
                        name:Department of Neurology, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Erin L. Abner
               affiliation:
                     name:University of Kentucky
                     address:
                        name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Bernard J. Wilfred
               affiliation:
                     name:University of Kentucky
                     address:
                        name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Wang-Xia Wang
               affiliation:
                     name:University of Kentucky
                     address:
                        name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Janna H. Neltner
               affiliation:
                     name:Sanders-Brown Center on Aging, University of Kentucky
                     address:
                        name:Division of Neuropathology, Department of Pathology, Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Michael Baker
               affiliation:
                     name:University of Kentucky
                     address:
                        name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:David W. Fardo
               affiliation:
                     name:University of Kentucky
                     address:
                        name:Department of Biostatistics, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Richard J. Kryscio
               affiliation:
                     name:University of Kentucky
                     address:
                        name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
                     name:University of Kentucky
                     address:
                        name:Department of Biostatistics, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
                     name:University of Kentucky
                     address:
                        name:Department of Statistics, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Stephen W. Scheff
               affiliation:
                     name:University of Kentucky
                     address:
                        name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
                     name:University of Kentucky
                     address:
                        name:Department of Anatomy and Neurobiology, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Gregory A. Jicha
               affiliation:
                     name:University of Kentucky
                     address:
                        name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
                     name:University of Kentucky
                     address:
                        name:Department of Neurology, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Kurt A. Jellinger
               affiliation:
                     name:Institute of Clinical Neurobiology
                     address:
                        name:Institute of Clinical Neurobiology, Vienna, Austria
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Linda J. Van Eldik
               affiliation:
                     name:University of Kentucky
                     address:
                        name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
                     name:University of Kentucky
                     address:
                        name:Department of Anatomy and Neurobiology, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Frederick A. Schmitt
               affiliation:
                     name:University of Kentucky
                     address:
                        name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
                     name:University of Kentucky
                     address:
                        name:Department of Neurology, University of Kentucky, Lexington, USA
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease
      description:Hippocampal sclerosis of aging (HS-Aging) is a causative factor in a large proportion of elderly dementia cases. The current definition of HS-Aging rests on pathologic criteria: neuronal loss and gliosis in the hippocampal formation that is out of proportion to AD-type pathology. HS-Aging is also strongly associated with TDP-43 pathology. HS-Aging pathology appears to be most prevalent in the oldest-old: autopsy series indicate that 5โ€“30ย % of nonagenarians have HS-Aging pathology. Among prior studies, differences in study design have contributed to the study-to-study variability in reported disease prevalence. The presence of HS-Aging pathology correlates with significant cognitive impairment which is often misdiagnosed as AD clinically. The antemortem diagnosis is further confounded by other diseases linked to hippocampal atrophy including frontotemporal lobar degeneration and cerebrovascular pathologies. Recent advances characterizing the neurocognitive profile of HS-Aging patients have begun to provide clues that may help identify living individuals with HS-Aging pathology. Structural brain imaging studies of research subjects followed to autopsy reveal hippocampal atrophy that is substantially greater in people with eventual HS-Aging pathology, compared to those with AD pathology alone. Data are presented from individuals who were followed with neurocognitive and neuroradiologic measurements, followed by neuropathologic evaluation at the University of Kentucky. Finally, we discuss factors that are hypothesized to cause or modify the disease. We conclude that the published literature on HS-Aging provides strong evidence of an important and under-appreciated brain disease of aging. Unfortunately, there is no therapy or preventive strategy currently available.
      datePublished:2013-07-18T00:00:00Z
      dateModified:2013-07-18T00:00:00Z
      pageStart:161
      pageEnd:177
      sameAs:https://doi.org/10.1007/s00401-013-1154-1
      keywords:
         TDP43
         TDP-43
         TARDBP
         Dementia
         Aging
         Neuropathology
         FTLD
         Epidemiology
         Genetics
         Cognition
         Neuroradiology
         MRI
         Hippocampus
         Pathology
         Arteriolosclerosis
         Cerebrovascular
         Oldest-old
         Neurosciences
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig3_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig4_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig5_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig6_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00401-013-1154-1/MediaObjects/401_2013_1154_Fig7_HTML.jpg
      isPartOf:
         name:Acta Neuropathologica
         issn:
            1432-0533
            0001-6322
         volumeNumber:126
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer Berlin Heidelberg
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Peter T. Nelson
            affiliation:
                  name:University of Kentucky
                  address:
                     name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
                  name:Sanders-Brown Center on Aging, University of Kentucky
                  address:
                     name:Division of Neuropathology, Department of Pathology, Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Charles D. Smith
            affiliation:
                  name:University of Kentucky
                  address:
                     name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
                  name:University of Kentucky
                  address:
                     name:Department of Neurology, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Erin L. Abner
            affiliation:
                  name:University of Kentucky
                  address:
                     name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Bernard J. Wilfred
            affiliation:
                  name:University of Kentucky
                  address:
                     name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Wang-Xia Wang
            affiliation:
                  name:University of Kentucky
                  address:
                     name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Janna H. Neltner
            affiliation:
                  name:Sanders-Brown Center on Aging, University of Kentucky
                  address:
                     name:Division of Neuropathology, Department of Pathology, Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Michael Baker
            affiliation:
                  name:University of Kentucky
                  address:
                     name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:David W. Fardo
            affiliation:
                  name:University of Kentucky
                  address:
                     name:Department of Biostatistics, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Richard J. Kryscio
            affiliation:
                  name:University of Kentucky
                  address:
                     name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
                  name:University of Kentucky
                  address:
                     name:Department of Biostatistics, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
                  name:University of Kentucky
                  address:
                     name:Department of Statistics, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Stephen W. Scheff
            affiliation:
                  name:University of Kentucky
                  address:
                     name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
                  name:University of Kentucky
                  address:
                     name:Department of Anatomy and Neurobiology, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Gregory A. Jicha
            affiliation:
                  name:University of Kentucky
                  address:
                     name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
                  name:University of Kentucky
                  address:
                     name:Department of Neurology, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Kurt A. Jellinger
            affiliation:
                  name:Institute of Clinical Neurobiology
                  address:
                     name:Institute of Clinical Neurobiology, Vienna, Austria
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Linda J. Van Eldik
            affiliation:
                  name:University of Kentucky
                  address:
                     name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
                  name:University of Kentucky
                  address:
                     name:Department of Anatomy and Neurobiology, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Frederick A. Schmitt
            affiliation:
                  name:University of Kentucky
                  address:
                     name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
                  name:University of Kentucky
                  address:
                     name:Department of Neurology, University of Kentucky, Lexington, USA
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Acta Neuropathologica
      issn:
         1432-0533
         0001-6322
      volumeNumber:126
Organization:
      name:Springer Berlin Heidelberg
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Kentucky
      address:
         name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:Sanders-Brown Center on Aging, University of Kentucky
      address:
         name:Division of Neuropathology, Department of Pathology, Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Department of Neurology, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:Sanders-Brown Center on Aging, University of Kentucky
      address:
         name:Division of Neuropathology, Department of Pathology, Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Department of Biostatistics, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Department of Biostatistics, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Department of Statistics, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Department of Anatomy and Neurobiology, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Department of Neurology, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:Institute of Clinical Neurobiology
      address:
         name:Institute of Clinical Neurobiology, Vienna, Austria
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Department of Anatomy and Neurobiology, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
         type:PostalAddress
      name:University of Kentucky
      address:
         name:Department of Neurology, University of Kentucky, Lexington, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Peter T. Nelson
      affiliation:
            name:University of Kentucky
            address:
               name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
            name:Sanders-Brown Center on Aging, University of Kentucky
            address:
               name:Division of Neuropathology, Department of Pathology, Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Charles D. Smith
      affiliation:
            name:University of Kentucky
            address:
               name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
            name:University of Kentucky
            address:
               name:Department of Neurology, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
      name:Erin L. Abner
      affiliation:
            name:University of Kentucky
            address:
               name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
      name:Bernard J. Wilfred
      affiliation:
            name:University of Kentucky
            address:
               name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
      name:Wang-Xia Wang
      affiliation:
            name:University of Kentucky
            address:
               name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
      name:Janna H. Neltner
      affiliation:
            name:Sanders-Brown Center on Aging, University of Kentucky
            address:
               name:Division of Neuropathology, Department of Pathology, Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
      name:Michael Baker
      affiliation:
            name:University of Kentucky
            address:
               name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
      name:David W. Fardo
      affiliation:
            name:University of Kentucky
            address:
               name:Department of Biostatistics, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
      name:Richard J. Kryscio
      affiliation:
            name:University of Kentucky
            address:
               name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
            name:University of Kentucky
            address:
               name:Department of Biostatistics, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
            name:University of Kentucky
            address:
               name:Department of Statistics, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
      name:Stephen W. Scheff
      affiliation:
            name:University of Kentucky
            address:
               name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
            name:University of Kentucky
            address:
               name:Department of Anatomy and Neurobiology, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
      name:Gregory A. Jicha
      affiliation:
            name:University of Kentucky
            address:
               name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
            name:University of Kentucky
            address:
               name:Department of Neurology, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
      name:Kurt A. Jellinger
      affiliation:
            name:Institute of Clinical Neurobiology
            address:
               name:Institute of Clinical Neurobiology, Vienna, Austria
               type:PostalAddress
            type:Organization
      name:Linda J. Van Eldik
      affiliation:
            name:University of Kentucky
            address:
               name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
            name:University of Kentucky
            address:
               name:Department of Anatomy and Neurobiology, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
      name:Frederick A. Schmitt
      affiliation:
            name:University of Kentucky
            address:
               name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
            name:University of Kentucky
            address:
               name:Department of Neurology, University of Kentucky, Lexington, USA
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
      name:Division of Neuropathology, Department of Pathology, Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
      name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
      name:Department of Neurology, University of Kentucky, Lexington, USA
      name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
      name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
      name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
      name:Division of Neuropathology, Department of Pathology, Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
      name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
      name:Department of Biostatistics, University of Kentucky, Lexington, USA
      name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
      name:Department of Biostatistics, University of Kentucky, Lexington, USA
      name:Department of Statistics, University of Kentucky, Lexington, USA
      name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
      name:Department of Anatomy and Neurobiology, University of Kentucky, Lexington, USA
      name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
      name:Department of Neurology, University of Kentucky, Lexington, USA
      name:Institute of Clinical Neurobiology, Vienna, Austria
      name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
      name:Department of Anatomy and Neurobiology, University of Kentucky, Lexington, USA
      name:Sanders-Brown Center on Aging, University of Kentucky, Lexington, USA
      name:Department of Neurology, University of Kentucky, Lexington, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {๐Ÿ”—}(434)

Analytics and Tracking {๐Ÿ“Š}

  • Google Tag Manager

Libraries {๐Ÿ“š}

  • Clipboard.js
  • Prism.js

CDN Services {๐Ÿ“ฆ}

  • Crossref

5.7s.