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LINK . SPRINGER . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Link.springer.com Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. CDN Services

We are analyzing https://link.springer.com/article/10.1007/s00395-016-0561-6.

Title:
Caveolin-1/-3: therapeutic targets for myocardial ischemia/reperfusion injury | Basic Research in Cardiology
Description:
Myocardial ischemia/reperfusion (I/R) injury is a major cause of morbidity and mortality worldwide. Caveolae, caveolin-1 (Cav-1), and caveolin-3 (Cav-3) are essential for the protective effects of conditioning against myocardial I/R injury. Caveolins are membrane-bound scaffolding proteins that compartmentalize and modulate signal transduction. In this review, we introduce caveolae and caveolins and briefly describe the interactions of caveolins in the cardiovascular diseases. We also review the roles of Cav-1/-3 in protection against myocardial ischemia and I/R injury, and in conditioning. Finally, we suggest several potential research avenues that may be of interest to clinicians and basic scientists. The information included, herein, is potentially useful for the design of future studies and should advance the investigation of caveolins as therapeutic targets.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

  • Education
  • Health & Fitness
  • Insurance

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

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How Does Link.springer.com Make Money? {💾}

We can't figure out the monetization strategy.

While many websites aim to make money, others are created to share knowledge or showcase creativity. People build websites for various reasons. This could be one of them. Link.springer.com might be plotting its profit, but the way they're doing it isn't detectable yet.

Keywords {🔍}

pubmed, article, google, scholar, cas, caveolin, central, cell, myocardial, injury, yang, caveolae, patel, biol, ischemic, preconditioning, heart, lisanti, wang, physiol, ischemiareperfusion, cardiac, res, roth, mol, caveolins, protein, cardioprotection, dois, tsutsumi, doi, cardiol, niesman, protection, expression, mice, cardiovasc, chem, kinase, circ, zhang, rat, head, insel, role, lipid, membrane, horikawa, medical, effects,

Topics {✒}

akt/gsk-3beta/caveolin signalling month download article/chapter hyperosmotic-stress-induced tyrosine phosphorylation regional myocardial ischemia–reperfusion myocardial ischemia/reperfusion injury muscle-specific caveolin-related protein bone marrow-derived cells small-molecule adipor agonist nitric oxide mechanism article basic research isoflurane-induced cardiac protection membrane-bound scaffolding proteins oxidative stress-induced phosphorylation nitric oxide synthase full article pdf caveolin-3-dependent cyclooxygenase-2 inhibition epigallocatechin-3-gallate-mediated cardioprotection myocardial ischemia–reperfusion caveolin-1 gene-disrupted mice myocardial infarct size myocardial hypertrophy induced zemljic-harpf ae ischemia/reperfusion injury ischemia reperfusion injury ischemia–reperfusion injury sevoflurane cardiac preconditioning caveolin-1/3 double-knockout mice permeability transition pore green tea extract risk signalling pathway nitric oxide signaling attenuating calcium overload ischemia/reperfusion ko anesthetic-induced preconditioning privacy choices/manage cookies adult cardiac myocytes cardiomyocyte apoptosis induced estrogen receptor alpha endothelial-rich source pritchard ka jr tsutsumi ym article yang ischaemia/reperfusion damage potential research avenues hsieh sr opioid-induced preconditioning caveolin induces cardioprotection familial hypertrophic cardiomyopathy nsaid-induced esophageal jasmin jf

Questions {❓}

  • Bulluck H, Hausenloy DJ (2015) Ischaemic conditioning: are we there yet?
  • Halestrap AP (2009) What is the mitochondrial permeability transition pore?
  • Lamont KT, Somers S, Lacerda L, Opie LH, Lecour S (2011) Is red wine a SAFE sip away from cardioprotection?
  • Ovize M, Baxter GF, Di Lisa F, Ferdinandy P, Garcia-Dorado D, Hausenloy DJ, Heusch G, Vinten-Johansen J, Yellon DM, Schulz R (2010) Postconditioning and protection from reperfusion injury: where do we stand?

Schema {đŸ—ș}

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         headline:Caveolin-1/-3: therapeutic targets for myocardial ischemia/reperfusion injury
         description:Myocardial ischemia/reperfusion (I/R) injury is a major cause of morbidity and mortality worldwide. Caveolae, caveolin-1 (Cav-1), and caveolin-3 (Cav-3) are essential for the protective effects of conditioning against myocardial I/R injury. Caveolins are membrane-bound scaffolding proteins that compartmentalize and modulate signal transduction. In this review, we introduce caveolae and caveolins and briefly describe the interactions of caveolins in the cardiovascular diseases. We also review the roles of Cav-1/-3 in protection against myocardial ischemia and I/R injury, and in conditioning. Finally, we suggest several potential research avenues that may be of interest to clinicians and basic scientists. The information included, herein, is potentially useful for the design of future studies and should advance the investigation of caveolins as therapeutic targets.
         datePublished:2016-06-09T00:00:00Z
         dateModified:2016-06-09T00:00:00Z
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      headline:Caveolin-1/-3: therapeutic targets for myocardial ischemia/reperfusion injury
      description:Myocardial ischemia/reperfusion (I/R) injury is a major cause of morbidity and mortality worldwide. Caveolae, caveolin-1 (Cav-1), and caveolin-3 (Cav-3) are essential for the protective effects of conditioning against myocardial I/R injury. Caveolins are membrane-bound scaffolding proteins that compartmentalize and modulate signal transduction. In this review, we introduce caveolae and caveolins and briefly describe the interactions of caveolins in the cardiovascular diseases. We also review the roles of Cav-1/-3 in protection against myocardial ischemia and I/R injury, and in conditioning. Finally, we suggest several potential research avenues that may be of interest to clinicians and basic scientists. The information included, herein, is potentially useful for the design of future studies and should advance the investigation of caveolins as therapeutic targets.
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         Cardioprotection
         Cardiology
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                     name:Department of Biomedical Engineering, The Fourth Military Medical University, Xi’an, China
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                     name:Department of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
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                     type:PostalAddress
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                     type:PostalAddress
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                  name:National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College
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                     name:State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
                     type:PostalAddress
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         name:Department of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
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               type:PostalAddress
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            name:The Fourth Military Medical University
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               type:PostalAddress
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            name:Nanjing University Medical School
            address:
               name:Department of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
               type:PostalAddress
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      name:Zhiqiang Ma
      affiliation:
            name:The Fourth Military Medical University
            address:
               name:Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi’an, China
               type:PostalAddress
            type:Organization
      name:Wei Hu
      affiliation:
            name:The Fourth Military Medical University
            address:
               name:Department of Biomedical Engineering, The Fourth Military Medical University, Xi’an, China
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      name:Dongjin Wang
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            name:Nanjing University Medical School
            address:
               name:Department of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
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      name:Shuai Jiang
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            name:The Fourth Military Medical University
            address:
               name:Department of Aerospace Medicine, The Fourth Military Medical University, Xi’an, China
               type:PostalAddress
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      name:Chongxi Fan
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            name:The Fourth Military Medical University
            address:
               name:Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi’an, China
               type:PostalAddress
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      name:Shouyin Di
      affiliation:
            name:The Fourth Military Medical University
            address:
               name:Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi’an, China
               type:PostalAddress
            type:Organization
      name:Dong Liu
      affiliation:
            name:National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College
            address:
               name:State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
               type:PostalAddress
            type:Organization
      name:Yang Sun
      affiliation:
            name:The Fourth Military Medical University
            address:
               name:Department of Geriatrics, Xijing Hospital, The Fourth Military Medical University, Xi’an, China
               type:PostalAddress
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      email:[email protected]
      name:Wei Yi
      affiliation:
            name:The Fourth Military Medical University
            address:
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      email:[email protected]
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      name:Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi’an, China
      name:Department of Biomedical Engineering, The Fourth Military Medical University, Xi’an, China
      name:Department of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
      name:Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi’an, China
      name:Department of Biomedical Engineering, The Fourth Military Medical University, Xi’an, China
      name:Department of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
      name:Department of Aerospace Medicine, The Fourth Military Medical University, Xi’an, China
      name:Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi’an, China
      name:Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi’an, China
      name:State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
      name:Department of Geriatrics, Xijing Hospital, The Fourth Military Medical University, Xi’an, China
      name:Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi’an, China
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External Links {🔗}(554)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

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CDN Services {📩}

  • Crossref

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