Here's how LINK.SPRINGER.COM makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

LINK . SPRINGER . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Link.springer.com Make Money
  6. Keywords
  7. Topics
  8. Schema
  9. External Links
  10. Analytics And Tracking
  11. Libraries
  12. CDN Services

We are analyzing https://link.springer.com/article/10.1007/s00395-008-0757-5.

Title:
Guggulsterone, an anti-inflammatory phytosterol, inhibits tissue factor and arterial thrombosis | Basic Research in Cardiology
Description:
Background The phytosterol guggulsterone is a potent anti-inflammatory mediator with less side effects than classic steroids. This study assesses the impact of guggulsterone on tissue factor (TF) expression and thrombus formation. Methods and results Guggulsterone inhibited TNF-α-induced endothelial TF protein expression and surface activity in a concentration-dependent manner; in contrast, dexamethasone did not affect TNF-α-induced TF expression. Guggulsterone enhanced endothelial tissue factor pathway inhibitor and impaired plasminogen activator inhibitor-1 as well as vascular cell adhesion molecule-1 protein. Real-time polymerase chain reaction revealed that guggulsterone inhibited TNF-α-induced TF mRNA expression; moreover, it impaired activation of the MAP kinases JNK and p38, while that of ERK remained unaffected. In vivo, guggulsterone inhibited TF activity and photochemical injury induced thrombotic occlusion of mouse carotid artery. Guggulsterone also inhibited TF expression, proliferation, and migration of vascular smooth muscle cells in a concentration-dependent manner. Conclusions Guggulsterone inhibits TF expression in vascular cells as well as thrombus formation in vivo; moreover, it impairs vascular smooth muscle cell activation. Hence, this phytosterol offers novel therapeutic options, in particular in inflammatory diseases associated with an increased risk of thrombosis.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

  • Education
  • Health & Fitness
  • Science

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We're unsure if the website is profiting.

Websites don't always need to be profitable; some serve as platforms for education or personal expression. Websites can serve multiple purposes. And this might be one of them. Link.springer.com might be plotting its profit, but the way they're doing it isn't detectable yet.

Keywords {🔍}

article, google, scholar, pubmed, cas, factor, tissue, guggulsterone, tanner, expression, gebhard, vascular, thrombosis, circulation, res, alexander, akhmedov, luscher, research, basic, phd, endothelial, inhibitor, activation, access, steffel, privacy, cookies, content, phytosterol, inhibits, catherine, stämpfli, camici, thomas, felix, activity, acute, foundation, publish, search, arterial, simon, breitenstein, erik, holy, lüscher, effects, formation, inhibited,

Topics {✒️}

guggulsterone inhibits nf-kappab month download article/chapter decreased c-reactive protein anti-apoptotic gene products inhibited tf expression european concerted action drug-eluting stent design inhibits tissue factor potent anti-inflammatory mediator article basic research vascular endothelial cells tissue factor modulates natural cholesterol-lowering agent plasminogen activator inhibitor full article pdf related subjects ikappabalpha kinase activation experimentally induced hyperlipemia anti-inflammatory phytosterol van der poll privacy choices/manage cookies transcription factors induced endotoxin-induced effects agarwal ss gupta rc tissue factor expert technical support author information authors drug-eluting stents arterial thrombosis altered activity patterns article gebhard check access instant access phytosterol guggulsterone acute ischaemic stroke acute coronary syndromes european economic area concentration-dependent manner erk remained unaffected mouse carotid artery age-dependent susceptibility human atherosclerotic plaques inhaled carbon monoxide bonizzi-theler foundation wolfermann nägeli foundation swiss heart foundation alexander breitenstein md acute myocardial infarction conditions privacy policy

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Guggulsterone, an anti-inflammatory phytosterol, inhibits tissue factor and arterial thrombosis
         description:The phytosterol guggulsterone is a potent anti-inflammatory mediator with less side effects than classic steroids. This study assesses the impact of guggulsterone on tissue factor (TF) expression and thrombus formation. Guggulsterone inhibited TNF-α-induced endothelial TF protein expression and surface activity in a concentration-dependent manner; in contrast, dexamethasone did not affect TNF-α-induced TF expression. Guggulsterone enhanced endothelial tissue factor pathway inhibitor and impaired plasminogen activator inhibitor-1 as well as vascular cell adhesion molecule-1 protein. Real-time polymerase chain reaction revealed that guggulsterone inhibited TNF-α-induced TF mRNA expression; moreover, it impaired activation of the MAP kinases JNK and p38, while that of ERK remained unaffected. In vivo, guggulsterone inhibited TF activity and photochemical injury induced thrombotic occlusion of mouse carotid artery. Guggulsterone also inhibited TF expression, proliferation, and migration of vascular smooth muscle cells in a concentration-dependent manner. Guggulsterone inhibits TF expression in vascular cells as well as thrombus formation in vivo; moreover, it impairs vascular smooth muscle cell activation. Hence, this phytosterol offers novel therapeutic options, in particular in inflammatory diseases associated with an increased risk of thrombosis.
         datePublished:2008-10-24T00:00:00Z
         dateModified:2008-10-24T00:00:00Z
         pageStart:285
         pageEnd:294
         sameAs:https://doi.org/10.1007/s00395-008-0757-5
         keywords:
            arterial thrombosis
            photochemical injury
            phytosterol
            tissue factor
            Cardiology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-008-0757-5/MediaObjects/395_2008_757_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-008-0757-5/MediaObjects/395_2008_757_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-008-0757-5/MediaObjects/395_2008_757_Fig3_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-008-0757-5/MediaObjects/395_2008_757_Fig4_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-008-0757-5/MediaObjects/395_2008_757_Fig5_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-008-0757-5/MediaObjects/395_2008_757_Fig6_HTML.gif
         isPartOf:
            name:Basic Research in Cardiology
            issn:
               1435-1803
               0300-8428
            volumeNumber:104
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Steinkopff-Verlag
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Catherine Gebhard
               affiliation:
                     name:University of Zurich
                     address:
                        name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University of Zurich
                     address:
                        name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University Hospital Zurich
                     address:
                        name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Simon F. Stämpfli
               affiliation:
                     name:University of Zurich
                     address:
                        name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University of Zurich
                     address:
                        name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University Hospital Zurich
                     address:
                        name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Caroline E. Gebhard
               affiliation:
                     name:University of Zurich
                     address:
                        name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University of Zurich
                     address:
                        name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Alexander Akhmedov
               affiliation:
                     name:University of Zurich
                     address:
                        name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University of Zurich
                     address:
                        name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Alexander Breitenstein
               affiliation:
                     name:University of Zurich
                     address:
                        name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University of Zurich
                     address:
                        name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University Hospital Zurich
                     address:
                        name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Giovanni G. Camici
               affiliation:
                     name:University of Zurich
                     address:
                        name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University of Zurich
                     address:
                        name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Erik W. Holy
               affiliation:
                     name:University of Zurich
                     address:
                        name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University of Zurich
                     address:
                        name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University Hospital Zurich
                     address:
                        name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Thomas F. Lüscher
               affiliation:
                     name:University of Zurich
                     address:
                        name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University of Zurich
                     address:
                        name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University Hospital Zurich
                     address:
                        name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Felix C. Tanner
               affiliation:
                     name:University of Zurich
                     address:
                        name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University of Zurich
                     address:
                        name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
                     name:University Hospital Zurich
                     address:
                        name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Guggulsterone, an anti-inflammatory phytosterol, inhibits tissue factor and arterial thrombosis
      description:The phytosterol guggulsterone is a potent anti-inflammatory mediator with less side effects than classic steroids. This study assesses the impact of guggulsterone on tissue factor (TF) expression and thrombus formation. Guggulsterone inhibited TNF-α-induced endothelial TF protein expression and surface activity in a concentration-dependent manner; in contrast, dexamethasone did not affect TNF-α-induced TF expression. Guggulsterone enhanced endothelial tissue factor pathway inhibitor and impaired plasminogen activator inhibitor-1 as well as vascular cell adhesion molecule-1 protein. Real-time polymerase chain reaction revealed that guggulsterone inhibited TNF-α-induced TF mRNA expression; moreover, it impaired activation of the MAP kinases JNK and p38, while that of ERK remained unaffected. In vivo, guggulsterone inhibited TF activity and photochemical injury induced thrombotic occlusion of mouse carotid artery. Guggulsterone also inhibited TF expression, proliferation, and migration of vascular smooth muscle cells in a concentration-dependent manner. Guggulsterone inhibits TF expression in vascular cells as well as thrombus formation in vivo; moreover, it impairs vascular smooth muscle cell activation. Hence, this phytosterol offers novel therapeutic options, in particular in inflammatory diseases associated with an increased risk of thrombosis.
      datePublished:2008-10-24T00:00:00Z
      dateModified:2008-10-24T00:00:00Z
      pageStart:285
      pageEnd:294
      sameAs:https://doi.org/10.1007/s00395-008-0757-5
      keywords:
         arterial thrombosis
         photochemical injury
         phytosterol
         tissue factor
         Cardiology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-008-0757-5/MediaObjects/395_2008_757_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-008-0757-5/MediaObjects/395_2008_757_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-008-0757-5/MediaObjects/395_2008_757_Fig3_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-008-0757-5/MediaObjects/395_2008_757_Fig4_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-008-0757-5/MediaObjects/395_2008_757_Fig5_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-008-0757-5/MediaObjects/395_2008_757_Fig6_HTML.gif
      isPartOf:
         name:Basic Research in Cardiology
         issn:
            1435-1803
            0300-8428
         volumeNumber:104
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Steinkopff-Verlag
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Catherine Gebhard
            affiliation:
                  name:University of Zurich
                  address:
                     name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University of Zurich
                  address:
                     name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University Hospital Zurich
                  address:
                     name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Simon F. Stämpfli
            affiliation:
                  name:University of Zurich
                  address:
                     name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University of Zurich
                  address:
                     name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University Hospital Zurich
                  address:
                     name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Caroline E. Gebhard
            affiliation:
                  name:University of Zurich
                  address:
                     name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University of Zurich
                  address:
                     name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Alexander Akhmedov
            affiliation:
                  name:University of Zurich
                  address:
                     name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University of Zurich
                  address:
                     name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Alexander Breitenstein
            affiliation:
                  name:University of Zurich
                  address:
                     name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University of Zurich
                  address:
                     name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University Hospital Zurich
                  address:
                     name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Giovanni G. Camici
            affiliation:
                  name:University of Zurich
                  address:
                     name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University of Zurich
                  address:
                     name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Erik W. Holy
            affiliation:
                  name:University of Zurich
                  address:
                     name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University of Zurich
                  address:
                     name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University Hospital Zurich
                  address:
                     name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Thomas F. Lüscher
            affiliation:
                  name:University of Zurich
                  address:
                     name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University of Zurich
                  address:
                     name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University Hospital Zurich
                  address:
                     name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Felix C. Tanner
            affiliation:
                  name:University of Zurich
                  address:
                     name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University of Zurich
                  address:
                     name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
                  name:University Hospital Zurich
                  address:
                     name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Basic Research in Cardiology
      issn:
         1435-1803
         0300-8428
      volumeNumber:104
Organization:
      name:Steinkopff-Verlag
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Zurich
      address:
         name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University Hospital Zurich
      address:
         name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University Hospital Zurich
      address:
         name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University Hospital Zurich
      address:
         name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University Hospital Zurich
      address:
         name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University Hospital Zurich
      address:
         name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University of Zurich
      address:
         name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
         type:PostalAddress
      name:University Hospital Zurich
      address:
         name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Catherine Gebhard
      affiliation:
            name:University of Zurich
            address:
               name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University of Zurich
            address:
               name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University Hospital Zurich
            address:
               name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
      name:Simon F. Stämpfli
      affiliation:
            name:University of Zurich
            address:
               name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University of Zurich
            address:
               name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University Hospital Zurich
            address:
               name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
      name:Caroline E. Gebhard
      affiliation:
            name:University of Zurich
            address:
               name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University of Zurich
            address:
               name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
      name:Alexander Akhmedov
      affiliation:
            name:University of Zurich
            address:
               name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University of Zurich
            address:
               name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
      name:Alexander Breitenstein
      affiliation:
            name:University of Zurich
            address:
               name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University of Zurich
            address:
               name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University Hospital Zurich
            address:
               name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
      name:Giovanni G. Camici
      affiliation:
            name:University of Zurich
            address:
               name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University of Zurich
            address:
               name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
      name:Erik W. Holy
      affiliation:
            name:University of Zurich
            address:
               name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University of Zurich
            address:
               name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University Hospital Zurich
            address:
               name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
      name:Thomas F. Lüscher
      affiliation:
            name:University of Zurich
            address:
               name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University of Zurich
            address:
               name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University Hospital Zurich
            address:
               name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
      name:Felix C. Tanner
      affiliation:
            name:University of Zurich
            address:
               name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University of Zurich
            address:
               name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
            name:University Hospital Zurich
            address:
               name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
      name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
      name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
      name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
      name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
      name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
      name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
      name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
      name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
      name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
      name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
      name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
      name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
      name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
      name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
      name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
      name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
      name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
      name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
      name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
      name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
      name:Cardiovascular Research, Institute of Physiology, University of Zurich, Zürich, Switzerland
      name:Center for Integrative Human Physiology, University of Zurich, Zürich, Switzerland
      name:Cardiology, Cardiovascular Center, University Hospital Zurich, Zürich, Switzerland
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(140)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js
  • Foundation
  • Prism.js

CDN Services {📦}

  • Crossref

4.31s.