We are analyzing https://link.springer.com/article/10.1007/s00394-008-0733-8.

Title:
Dietary folate intake during pregnancy and birth weight in Japan | European Journal of Nutrition
Description:
Inadequate folate status has been associated with many negative reproductive outcomes, such as neural tube defects (NTD), low birth weight and placental abruption. The objectives of this study were to evaluate the levels of dietary folate intake during pregnancy in Japanese women and the subsequent birth weight of their babies. A longitudinal prospective study was conducted with 197 women with a singleton pregnancy in 2005. Dietary folate was investigated 3 times: in the first trimester at 12 weeks, in the second trimester at 20 weeks and in third trimester at 32 weeks using a diet history questionnaire (DHQ). Non fasting blood samples were collected from the women for measurement of homocysteine, hemoglobin, ferritin, unbound iron-binding capacity (UIBC) and total iron-binding capacity (TIBC). Energy intake increased as pregnancy advanced, but not significantly. The daily intake of folate increased from 248.5 ± 113.1 µg/d in the first trimester to 275.4 ± 100.2 µg/d in the third trimester (P = 0.04). This was well below the recommended level of 440 µg/d and only 10% of mothers were above the levels. In the third trimester, plasma homocysteine concentration was significantly higher in the low folate group of less than 250 µg/d (P = 0.02), but not the first and second trimesters. Dietary folate intake and plasma homocysteine concentrations were not likely to be predictors of birth weight in our subjects. Our study shows that Japanese women’s energy and folate intakes do not meet their energy needs during pregnancy and are at an extremely low recommended dietary allowance level throughout pregnancy.
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Keywords {🔍}

folate, google, scholar, article, pregnancy, japan, dietary, cas, health, homocysteine, study, intake, weight, birth, japanese, maternal, nutr, research, nutrition, women, trimester, access, defects, plasma, open, folic, acid, obstet, gynecol, tokyo, privacy, cookies, content, journal, neural, tube, levels, clin, ministry, labour, european, information, publish, search, watanabe, total, µgd, concentration, intakes, vitamin,

Topics {✒️}

month download article/chapter folate-related genetic factors unbound iron-binding capacity total iron-binding capacity longitudinal prospective study low birth weight folic acid fortification article european journal national nutrition survey full article pdf low folate group privacy choices/manage cookies neural tube defects neural-tube defects dietary folate intake diet history questionnaire daiichi shuppan publishing enriched grain products subsequent birth weight plasma homocysteine concentration related subjects 3-day diet record micronutrient intake measured check access instant access european economic area plasma homocysteine concentrations adverse pregnancy outcome plasma folate concentration dietary folate intakes yasushi nagai neonatal weight occurring fasting blood samples folic acid enzymatic colorimetric assay dietary food folate accelerated folate breakdown folate biomarker profiles child health statistics google scholar article watanabe conditions privacy policy negative reproductive outcomes shino-test corporation journal finder publish accepting optional cookies hiroko watanabe birth weight recommended level birth defects

Questions {❓}

Goldenberg RL, Tamura R, Cliver SP, et al (1992) Serum folate and fetal growth retardation: a matter of compliance?

Schema {🗺️}

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         headline:Dietary folate intake during pregnancy and birth weight in Japan
         description:Inadequate folate status has been associated with many negative reproductive outcomes, such as neural tube defects (NTD), low birth weight and placental abruption. The objectives of this study were to evaluate the levels of dietary folate intake during pregnancy in Japanese women and the subsequent birth weight of their babies. A longitudinal prospective study was conducted with 197 women with a singleton pregnancy in 2005. Dietary folate was investigated 3 times: in the first trimester at 12 weeks, in the second trimester at 20 weeks and in third trimester at 32 weeks using a diet history questionnaire (DHQ). Non fasting blood samples were collected from the women for measurement of homocysteine, hemoglobin, ferritin, unbound iron-binding capacity (UIBC) and total iron-binding capacity (TIBC). Energy intake increased as pregnancy advanced, but not significantly. The daily intake of folate increased from 248.5 ± 113.1 µg/d in the first trimester to 275.4 ± 100.2 µg/d in the third trimester (P = 0.04). This was well below the recommended level of 440 µg/d and only 10% of mothers were above the levels. In the third trimester, plasma homocysteine concentration was significantly higher in the low folate group of less than 250 µg/d (P = 0.02), but not the first and second trimesters. Dietary folate intake and plasma homocysteine concentrations were not likely to be predictors of birth weight in our subjects. Our study shows that Japanese women’s energy and folate intakes do not meet their energy needs during pregnancy and are at an extremely low recommended dietary allowance level throughout pregnancy.
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      headline:Dietary folate intake during pregnancy and birth weight in Japan
      description:Inadequate folate status has been associated with many negative reproductive outcomes, such as neural tube defects (NTD), low birth weight and placental abruption. The objectives of this study were to evaluate the levels of dietary folate intake during pregnancy in Japanese women and the subsequent birth weight of their babies. A longitudinal prospective study was conducted with 197 women with a singleton pregnancy in 2005. Dietary folate was investigated 3 times: in the first trimester at 12 weeks, in the second trimester at 20 weeks and in third trimester at 32 weeks using a diet history questionnaire (DHQ). Non fasting blood samples were collected from the women for measurement of homocysteine, hemoglobin, ferritin, unbound iron-binding capacity (UIBC) and total iron-binding capacity (TIBC). Energy intake increased as pregnancy advanced, but not significantly. The daily intake of folate increased from 248.5 ± 113.1 µg/d in the first trimester to 275.4 ± 100.2 µg/d in the third trimester (P = 0.04). This was well below the recommended level of 440 µg/d and only 10% of mothers were above the levels. In the third trimester, plasma homocysteine concentration was significantly higher in the low folate group of less than 250 µg/d (P = 0.02), but not the first and second trimesters. Dietary folate intake and plasma homocysteine concentrations were not likely to be predictors of birth weight in our subjects. Our study shows that Japanese women’s energy and folate intakes do not meet their energy needs during pregnancy and are at an extremely low recommended dietary allowance level throughout pregnancy.
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