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Title:
Hepatoblastoma associated with Beckwith-Wiedemann syndrome and hemihypertrophy | Pediatric Surgery International
Description:
Both Beckwith-Wiedemann syndrome (BWS) and hemihypertrophy (HH) have been recognized to be overgrowth syndromes associated with an increased risk of cancer. We report an infant with hepatoblastoma associated with both BWS and HH in whom high serum alpha-fetoprotein (AFP) levels persisted even after complete tumor resection with no tumor recurrence. This phenomenon might be partly due to the nature of the proliferative disease. It is important to recognize that in some infants with BWS prolonged high serum AFP levels mimic the existence of a tumor, and that treatment should be based not only on AFP measurement, but also on repeated radiologic imaging.
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article, syndrome, privacy, cookies, content, beckwithwiedemann, access, information, publish, search, surgery, hepatoblastoma, hemihypertrophy, data, log, journal, research, hamada, takada, fukunaga, bws, high, alphafetoprotein, afp, tumor, nature, chapter, discover, springer, optional, personal, parties, policy, find, track, pediatric, international, report, cite, hioki, explore, serum, levels, disease, institution, hepatocellular, carcinoma, open, related, subjects,
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high serum alpha-fetoprotein month download article/chapter hepatocellular carcinoma beckwith-wiedemann syndrome high alpha-fetoprotein related subjects privacy choices/manage cookies full article pdf european economic area scope submit manuscript repeated radiologic imaging kansai medical university conditions privacy policy check access instant access accepting optional cookies complete tumor resection main content log journal finder publish article log levels persisted article cite article hamada information privacy policy personal data books a afp measurement optional cookies manage preferences hepatoblastoma data protection essential cookies cookies skip subscription content similar content surgery institution subscribe journal publish nature usage analysis social media varying standards april 2003 volumeΒ 19 overgrowth syndromes increased risk tumor recurrence partly due latest articles machine learning
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headline:Hepatoblastoma associated with Beckwith-Wiedemann syndrome and hemihypertrophy
description:Both Beckwith-Wiedemann syndrome (BWS) and hemihypertrophy (HH) have been recognized to be overgrowth syndromes associated with an increased risk of cancer. We report an infant with hepatoblastoma associated with both BWS and HH in whom high serum alpha-fetoprotein (AFP) levels persisted even after complete tumor resection with no tumor recurrence. This phenomenon might be partly due to the nature of the proliferative disease. It is important to recognize that in some infants with BWS prolonged high serum AFP levels mimic the existence of a tumor, and that treatment should be based not only on AFP measurement, but also on repeated radiologic imaging.
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Pediatrics
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Pediatric Surgery
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description:Both Beckwith-Wiedemann syndrome (BWS) and hemihypertrophy (HH) have been recognized to be overgrowth syndromes associated with an increased risk of cancer. We report an infant with hepatoblastoma associated with both BWS and HH in whom high serum alpha-fetoprotein (AFP) levels persisted even after complete tumor resection with no tumor recurrence. This phenomenon might be partly due to the nature of the proliferative disease. It is important to recognize that in some infants with BWS prolonged high serum AFP levels mimic the existence of a tumor, and that treatment should be based not only on AFP measurement, but also on repeated radiologic imaging.
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