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Title:
Comparison of the diagnostic performance of digital breast tomosynthesis and magnetic resonance imaging added to digital mammography in women with known breast cancers | European Radiology
Description:
Objectives To compare the diagnostic performance of digital breast tomosynthesis (DBT) and magnetic resonance imaging (MRI) added to mammography in women with known breast cancers. Methods Three radiologists independently reviewed image sets of 172 patients with 184 cancers; mammography alone, DBT plus mammography and MRI plus mammography, and scored for cancer probability using the Breast Imaging Reporting and Data System (BI-RADS). Jack-knife alternative free-response receiver-operating characteristic (JAFROC), which allows diagnostic performance estimation using single lesion as a statistical unit in a cancer-only population, was used. Sensitivity and positive predictive value (PPV) were compared using the McNemar and Fisher-exact tests. Results The JAFROC figures of merit (FOMs) was lower in DBT plus mammography (0.937) than MRI plus mammography (0.978, Pβ=β0.0006) but higher than mammography alone (0.900, Pβ=β0 .0013). The sensitivity was lower in DBT plus mammography (88.2 %) than MRI plus mammography (97.8 %) but higher than mammography alone (78.3 %, both Pβ<β0 .0001). The PPV was significantly higher in DBT plus mammography (93.3 %) than MRI plus mammography (89.6 %, Pβ=β0 .0282). Conclusions DBT provided lower diagnostic performance than MRI as an adjunctive imaging to mammography. However, DBT had higher diagnostic performance than mammography and higher PPV than MRI. Key Points β’ Digital breast tomosynthesis (DBT) plus mammography was compared with MRI plus mammography. β’ DBT had lower sensitivity and higher PPV than MRI. β’ DBT had higher diagnostic performance than mammography.
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Keywords {π}
mammography, breast, article, pubmed, google, scholar, digital, tomosynthesis, imaging, radiology, cancer, performance, mri, diagnostic, dbt, screening, seoul, comparison, magnetic, resonance, women, higher, radiol, study, cas, data, access, korea, university, privacy, cookies, content, research, chang, moon, preoperative, ultrasound, eur, hospital, department, publish, search, cancers, manuscript, min, hye, sensitivity, ppv, lower, subjects,
Topics {βοΈ}
month download article/chapter magnetic resonance imaging hye ryoung koo population-based screening program core medical device hyeong-gon moon population breast-cancer screening full-field digital mammography full article pdf jung min chang privacy choices/manage cookies european economic area breast imaging reporting advanced imaging techniques breast mr imaging gangnam severance hospital berg wa hanyang university college yonsei university college article kim breast cancer screening fisher-exact tests patient-level analyses signal intensity time gangnan healthcare center electronic supplementary material digital breast tomosynthesis assessing radiologist performance tomosynthesis examinations rated diagnostic performance estimation conditions privacy policy high familial risk pure ductal carcinoma invasive breast carcinoma early clinical experience mammography versus mammography chris woo prospective observational study observer performance study combined digital mammography conventional digital mammography 3d digital mammography accepting optional cookies bi-rads rafferty ea haas bm annual screening ultrasound written informed consent preoperative breast mri article log
Questions {β}
- Kuhl CK, Mielcareck P, Klaschik S et al (1999) Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions?
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headline:Comparison of the diagnostic performance of digital breast tomosynthesis and magnetic resonance imaging added to digital mammography in women with known breast cancers
description:To compare the diagnostic performance of digital breast tomosynthesis (DBT) and magnetic resonance imaging (MRI) added to mammography in women with known breast cancers. Three radiologists independently reviewed image sets of 172 patients with 184 cancers; mammography alone, DBT plus mammography and MRI plus mammography, and scored for cancer probability using the Breast Imaging Reporting and Data System (BI-RADS). Jack-knife alternative free-response receiver-operating characteristic (JAFROC), which allows diagnostic performance estimation using single lesion as a statistical unit in a cancer-only population, was used. Sensitivity and positive predictive value (PPV) were compared using the McNemar and Fisher-exact tests. The JAFROC figures of merit (FOMs) was lower in DBT plus mammography (0.937) than MRI plus mammography (0.978, Pβ=β0.0006) but higher than mammography alone (0.900, Pβ=β0 .0013). The sensitivity was lower in DBT plus mammography (88.2Β %) than MRI plus mammography (97.8Β %) but higher than mammography alone (78.3Β %, both Pβ<β0 .0001). The PPV was significantly higher in DBT plus mammography (93.3Β %) than MRI plus mammography (89.6Β %, Pβ=β0 .0282). DBT provided lower diagnostic performance than MRI as an adjunctive imaging to mammography. However, DBT had higher diagnostic performance than mammography and higher PPV than MRI. β’ Digital breast tomosynthesis (DBT) plus mammography was compared with MRI plus mammography.
β’ DBT had lower sensitivity and higher PPV than MRI.
β’ DBT had higher diagnostic performance than mammography.
datePublished:2015-09-16T00:00:00Z
dateModified:2015-09-16T00:00:00Z
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Magnetic resonance imaging
Imaging
Three-dimensional, mammography
Breast neoplasms/pathology
Sensitivity and specificity
Imaging / Radiology
Diagnostic Radiology
Interventional Radiology
Neuroradiology
Ultrasound
Internal Medicine
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headline:Comparison of the diagnostic performance of digital breast tomosynthesis and magnetic resonance imaging added to digital mammography in women with known breast cancers
description:To compare the diagnostic performance of digital breast tomosynthesis (DBT) and magnetic resonance imaging (MRI) added to mammography in women with known breast cancers. Three radiologists independently reviewed image sets of 172 patients with 184 cancers; mammography alone, DBT plus mammography and MRI plus mammography, and scored for cancer probability using the Breast Imaging Reporting and Data System (BI-RADS). Jack-knife alternative free-response receiver-operating characteristic (JAFROC), which allows diagnostic performance estimation using single lesion as a statistical unit in a cancer-only population, was used. Sensitivity and positive predictive value (PPV) were compared using the McNemar and Fisher-exact tests. The JAFROC figures of merit (FOMs) was lower in DBT plus mammography (0.937) than MRI plus mammography (0.978, Pβ=β0.0006) but higher than mammography alone (0.900, Pβ=β0 .0013). The sensitivity was lower in DBT plus mammography (88.2Β %) than MRI plus mammography (97.8Β %) but higher than mammography alone (78.3Β %, both Pβ<β0 .0001). The PPV was significantly higher in DBT plus mammography (93.3Β %) than MRI plus mammography (89.6Β %, Pβ=β0 .0282). DBT provided lower diagnostic performance than MRI as an adjunctive imaging to mammography. However, DBT had higher diagnostic performance than mammography and higher PPV than MRI. β’ Digital breast tomosynthesis (DBT) plus mammography was compared with MRI plus mammography.
β’ DBT had lower sensitivity and higher PPV than MRI.
β’ DBT had higher diagnostic performance than mammography.
datePublished:2015-09-16T00:00:00Z
dateModified:2015-09-16T00:00:00Z
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Magnetic resonance imaging
Imaging
Three-dimensional, mammography
Breast neoplasms/pathology
Sensitivity and specificity
Imaging / Radiology
Diagnostic Radiology
Interventional Radiology
Neuroradiology
Ultrasound
Internal Medicine
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