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Adult-onset Stillâs disease and pregnancy: about ten cases and review of the literature | Rheumatology International
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Little is known about the interactions between adult-onset Stillâs disease (AOSD) and pregnancy. In an attempt to clarify the link between these 2 conditions, we retrospectively analyzed patients registered as suffering from AOSD seen in our university hospital. A total of 57 patients, among them 30 women, were diagnosed. Ten pregnancies in 8 women were identified. Three cases manifested AOSD in their first trimester, all treated with prednisone. Premature births and flares occurred in 2 patients. One patient developed a monocyclic AOSD during her second pregnancyâs postpartum. In the 4 other cases, AOSD was known and quiescent before pregnancy. One patient had 2 pregnancies without any flare or complication. One patient experienced her first pregnancy while under treatment and presented a late flare 8 months after delivery. The third patient developed exacerbation in the first trimester of her second pregnancy which was treated with IgIV alone. The last one presented her first pregnancy 7 years after diagnosis. A prednisone-treated systemic flare occurred during the first trimester without later complication. Based on our own experience and the analysis of only two series of the literature, including, respectively, 4 and 5 patients, we suggest that two settings could be distinguished. First, AOSD can occur during pregnancy and can be responsible for obstetrical complications. Then, in patients with known AOSD, the second trimester and postpartum appear to be periods exposing to disease recurrence. Thus, we recommend a close multidisciplinary monitoring by a rheumatologist and an obstetrician prior to, during and after pregnancies.
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disease, article, stills, pregnancy, pubmed, google, scholar, adultonset, patients, rheumatol, aosd, france, privacy, cookies, gerfaudvalentin, university, outcome, cas, adult, lyon, content, publish, search, cases, literature, hospital, pregnancies, trimester, patient, access, medicine, department, data, information, log, journal, research, ten, review, april, hot, huissoud, broussolle, seve, treated, flare, discover, int, onset, download,
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month download article/chapter full article pdf privacy choices/manage cookies article gerfaud-valentin european economic area scope submit manuscript late flare 8Â months close multidisciplinary monitoring schumacher hr jr il-1 receptor antagonist pregnancy outcome successful outcome accepting optional cookies conditions privacy policy patient developed exacerbation article log journal finder publish university hospital obstetrics author correspondence check access article cite instant access cases manifested aosd 1007/s00296-009-1291 related subjects privacy policy personal data flares occurred books a adult-onset adult onset optional cookies manage preferences subscription content data protection seve department essential cookies cookies skip patient developed institution subscribe pregnancy 7Â years gerfaud-valentin journal publish social media varying standards ten cases premature births patient experienced obstetrical complications
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headline:Adult-onset Stillâs disease and pregnancy: about ten cases and review of the literature
description:Little is known about the interactions between adult-onset Stillâs disease (AOSD) and pregnancy. In an attempt to clarify the link between these 2 conditions, we retrospectively analyzed patients registered as suffering from AOSD seen in our university hospital. A total of 57 patients, among them 30 women, were diagnosed. Ten pregnancies in 8 women were identified. Three cases manifested AOSD in their first trimester, all treated with prednisone. Premature births and flares occurred in 2 patients. One patient developed a monocyclic AOSD during her second pregnancyâs postpartum. In the 4 other cases, AOSD was known and quiescent before pregnancy. One patient had 2 pregnancies without any flare or complication. One patient experienced her first pregnancy while under treatment and presented a late flare 8 months after delivery. The third patient developed exacerbation in the first trimester of her second pregnancy which was treated with IgIV alone. The last one presented her first pregnancy 7 years after diagnosis. A prednisone-treated systemic flare occurred during the first trimester without later complication. Based on our own experience and the analysis of only two series of the literature, including, respectively, 4 and 5 patients, we suggest that two settings could be distinguished. First, AOSD can occur during pregnancy and can be responsible for obstetrical complications. Then, in patients with known AOSD, the second trimester and postpartum appear to be periods exposing to disease recurrence. Thus, we recommend a close multidisciplinary monitoring by a rheumatologist and an obstetrician prior to, during and after pregnancies.
datePublished:2013-04-27T00:00:00Z
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headline:Adult-onset Stillâs disease and pregnancy: about ten cases and review of the literature
description:Little is known about the interactions between adult-onset Stillâs disease (AOSD) and pregnancy. In an attempt to clarify the link between these 2 conditions, we retrospectively analyzed patients registered as suffering from AOSD seen in our university hospital. A total of 57 patients, among them 30 women, were diagnosed. Ten pregnancies in 8 women were identified. Three cases manifested AOSD in their first trimester, all treated with prednisone. Premature births and flares occurred in 2 patients. One patient developed a monocyclic AOSD during her second pregnancyâs postpartum. In the 4 other cases, AOSD was known and quiescent before pregnancy. One patient had 2 pregnancies without any flare or complication. One patient experienced her first pregnancy while under treatment and presented a late flare 8 months after delivery. The third patient developed exacerbation in the first trimester of her second pregnancy which was treated with IgIV alone. The last one presented her first pregnancy 7 years after diagnosis. A prednisone-treated systemic flare occurred during the first trimester without later complication. Based on our own experience and the analysis of only two series of the literature, including, respectively, 4 and 5 patients, we suggest that two settings could be distinguished. First, AOSD can occur during pregnancy and can be responsible for obstetrical complications. Then, in patients with known AOSD, the second trimester and postpartum appear to be periods exposing to disease recurrence. Thus, we recommend a close multidisciplinary monitoring by a rheumatologist and an obstetrician prior to, during and after pregnancies.
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- How much does https://support.springernature.com/en/support/solutions/articles/6000255911-subscription-cancellations pull in monthly?
- How much does https://www.springernature.com/ rake in every month?
Analytics and Tracking {đ}
- Google Tag Manager
Libraries {đ}
- Clipboard.js
- Prism.js
CDN Services {đŠ}
- Crossref