We are analyzing https://link.springer.com/article/10.1007/s00294-009-0235-0.

Title:
Carotenoids and carotenogenic genes in Podospora anserina: engineering of the carotenoid composition extends the life span of the mycelium | Current Genetics
Description:
Carotenoids have been identified in the fungus Podospora anserina and a parallel pathway to neurosporene and β-carotene was established. Three genes for the β-carotene branch have been cloned and their function elucidated. They correspond to the al-1, al-2 and al-3 genes from Neurospora crassa. They were individually and in combinations over-expressed in P. anserina in order to modify the carotenoid composition qualitatively and quantitatively. In the resulting transformants, carotenoid synthesis was up to eightfold increased and several intermediates of the pathway together with special cyclic carotenoids, β-zeacarotene and 7,8-dihydro-β-carotene, accumulated. All transformants with an over-expressed al-2 gene (encoding a phytoene synthase and a lycopene cyclase) displayed up to 31% prolonged life span.
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Keywords {🔍}

google, scholar, article, cas, pubmed, carotenoid, carotenoids, gene, sandmann, anserina, podospora, pathway, osiewacz, neurospora, fungal, crassa, biosynthesis, genes, production, mol, genet, microbiol, van, privacy, cookies, content, engineering, life, span, breitenbach, access, biol, misawa, analysis, information, publish, research, search, genetics, composition, scheckhuber, phytoene, synthase, fungi, structure, acta, phytochem, avalos, biophys, molecular,

Topics {✒️}

month download article/chapter max-von-laue-str c30-bonded stationary phase related subjects carotenoid acid neurosporaxanthin beta-carotene 3-hydroxylase/4-ketolase metabolic engineering target van ooyen aj full article pdf privacy choices/manage cookies fungal carotenoids de vries rp neurospora carotenoid pathway carotenoid biosynthesis pathway carotenoid biosynthetic pathway van den berg ylo-1 gene encodes carotenoid biosynthetic gene data protection engineered stationary phases metabolic engineering fungus podospora anserina ascomycete podospora anserina carotenoid oxygenase family check access instant access gerhard sandmann gene products expressed iii-nouveaux carotenoides notamment sous forme variable chain length electrophoretically separated chromosomes transgenic mice carrying healthy ageing discomycete scutellinia umbrarum grant fp7-kbbe-2007-207948 excellence macromolecular complexes carotenoid composition extends carotenoid composition qualitatively article strobel van ooyen ajj special cyclic carotenoids conditions privacy policy european economic area aldehyde dehydrogenase responsible mating-type locus jürgen breitenbach blue light responses pathway delivering copper astaxanthin synthase gene

Questions {❓}

Harman D (1972) The biologic clock: the mitochondria?

Schema {🗺️}

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         description:Carotenoids have been identified in the fungus Podospora anserina and a parallel pathway to neurosporene and β-carotene was established. Three genes for the β-carotene branch have been cloned and their function elucidated. They correspond to the al-1, al-2 and al-3 genes from Neurospora crassa. They were individually and in combinations over-expressed in P. anserina in order to modify the carotenoid composition qualitatively and quantitatively. In the resulting transformants, carotenoid synthesis was up to eightfold increased and several intermediates of the pathway together with special cyclic carotenoids, β-zeacarotene and 7,8-dihydro-β-carotene, accumulated. All transformants with an over-expressed al-2 gene (encoding a phytoene synthase and a lycopene cyclase) displayed up to 31% prolonged life span.
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         Biochemistry
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         Plant Sciences
         Proteomics
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