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Title:
Genetic conservation versus variability in mitochondria: the architecture of the mitochondrial genome in the petite-negative yeast Schizosaccharomyces pombe | Current Genetics
Description:
The great amount of molecular information and the many molecular genetic techniques available make Schizosaccharomyces pombe an ideal model eukaryote, complementary to the budding yeast Saccharomyces cerevisiae. In particular, mechanisms involved in mitochiondrial (mt) biogenesis in fission yeast are more similar to higher eukaryotes than to budding yeast. In this review, recent findings on mt morphogenesis, DNA replication and gene expression in this model organism are summarised. A second aspect is the organisation of the mt genome in fission yeast. On the one hand, fission yeast has a strong tendency to maintain mtDNA intact; and, on the other hand, the mt genomes of naturally occurring strains show a great variability. Therefore, the molecular mechanisms behind the susceptibility to mutations in the mtDNA and the mechanisms that promote sequence variations during the evolution of the genome in fission yeast mitochondria are discussed.
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Keywords {🔍}
google, scholar, pubmed, cas, mitochondrial, yeast, article, pombe, schizosaccharomyces, cell, fission, dna, gene, biol, wolf, mol, genome, genet, group, intron, introns, mitochondria, saccharomyces, cerevisiae, schäfer, gen, curr, res, characterization, mutations, petite, sci, lang, biochem, nuclear, evolution, mutation, acids, rna, cox, genetics, genetic, petitenegative, mechanisms, access, biophys, yeasts, nucleic, endonuclease, information,
Topics {✒️}
month download article/chapter holliday junction-resolving enzyme morphogenetic-mutant saccharomyces cerevisiae intramitochondrial dynamin-related gtpase mitochondrial dynamin-related protein ethidium bromide-induced loss adams ae small ribosomal rna intron encoded proteins i-scai mitochondrial group fungal mitochondrial genomes circular-mapping mitochondrial genomes ribosomal proteins full article pdf yeasts saccharomyces cerevisiae site-specific genomic instabilities related subjects yeast schizosaccharomyces pombe pulsed-field electrophoresis clark-walker gd privacy choices/manage cookies intron closely related molecular genetic techniques group ii intron petite negative yeasts schizosaccharomyces pombe studied schizosaccharomyces pombe pmf1p schizosaccharomyces pombe operates species schizosaccharomyces pombe rho− yeast cells yeast kluyveromyces lactis gene encoding subunit 3 chen xj catalytic sector f1 14 kda subunit vii petite-positive yeast dimensional gel electrophoresis check access multiple homing pathways instant access saccharomyces cerevisiae kluyveromyces lactis occurs kluyveromyces lactis occur ap4a phosphorylase ii resolving enzyme ydc2 make schizosaccharomyces pombe mitochondrial mutator phenotype group ii introns ferat jl yeast mitochondrial gene
Questions {❓}
- Forsburg SL (1999) The best yeast?
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headline:Genetic conservation versus variability in mitochondria: the architecture of the mitochondrial genome in the petite-negative yeast Schizosaccharomyces pombe
description: The great amount of molecular information and the many molecular genetic techniques available make Schizosaccharomyces pombe an ideal model eukaryote, complementary to the budding yeast Saccharomyces cerevisiae. In particular, mechanisms involved in mitochiondrial (mt) biogenesis in fission yeast are more similar to higher eukaryotes than to budding yeast. In this review, recent findings on mt morphogenesis, DNA replication and gene expression in this model organism are summarised. A second aspect is the organisation of the mt genome in fission yeast. On the one hand, fission yeast has a strong tendency to maintain mtDNA intact; and, on the other hand, the mt genomes of naturally occurring strains show a great variability. Therefore, the molecular mechanisms behind the susceptibility to mutations in the mtDNA and the mechanisms that promote sequence variations during the evolution of the genome in fission yeast mitochondria are discussed.
datePublished:2003-05-09T00:00:00Z
dateModified:2003-05-09T00:00:00Z
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keywords:
Mitochiondrial biogenesis
Petite-negative yeast
Group I intron homing
Group II intron retro-homing
Microbial Genetics and Genomics
Microbiology
Biochemistry
general
Cell Biology
Plant Sciences
Proteomics
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headline:Genetic conservation versus variability in mitochondria: the architecture of the mitochondrial genome in the petite-negative yeast Schizosaccharomyces pombe
description: The great amount of molecular information and the many molecular genetic techniques available make Schizosaccharomyces pombe an ideal model eukaryote, complementary to the budding yeast Saccharomyces cerevisiae. In particular, mechanisms involved in mitochiondrial (mt) biogenesis in fission yeast are more similar to higher eukaryotes than to budding yeast. In this review, recent findings on mt morphogenesis, DNA replication and gene expression in this model organism are summarised. A second aspect is the organisation of the mt genome in fission yeast. On the one hand, fission yeast has a strong tendency to maintain mtDNA intact; and, on the other hand, the mt genomes of naturally occurring strains show a great variability. Therefore, the molecular mechanisms behind the susceptibility to mutations in the mtDNA and the mechanisms that promote sequence variations during the evolution of the genome in fission yeast mitochondria are discussed.
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Mitochiondrial biogenesis
Petite-negative yeast
Group I intron homing
Group II intron retro-homing
Microbial Genetics and Genomics
Microbiology
Biochemistry
general
Cell Biology
Plant Sciences
Proteomics
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