LINK . SPRINGER . COM {}

Matching Content Categories {📚}

• Science
• Mobile Technology & AI
• Telecommunications

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 7,626,932 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We see no obvious way the site makes money.

Not all websites focus on profit; some are designed to educate, connect people, or share useful tools. People create websites for numerous reasons. And this could be one such example. Link.springer.com could be getting rich in stealth mode, or the way it's monetizing isn't detectable.

Keywords {🔍}

cells, article, melanoma, tübingen, access, privacy, cookies, content, research, search, peptide, information, publish, cancer, immunology, mhcclassiirestricted, responses, vitro, synthetic, peptides, antigens, data, log, journal, tumourspecific, sensitization, annexin, eluted, adibzadeh, halder, molecules, fas, class, open, discover, mhc, tumour, university, medical, germany, springer, optional, personal, parties, policy, find, track, immunotherapy, august, cite,

Topics {✒️}

tumour-specific mhc-class-ii-restricted responses effective mhc-class-ii-restricted recognition hla-dr-matched normal donors' synthetic peptide antigens potential fas/fas-ligand interactions targets survivin-2b80-88/hla month download article/chapter peptide-mhc hla-dr molecules mhc class tumour immunology group article cancer immunology coexpressing high levels annexin ii eluted full article pdf privacy choices/manage cookies hla-drb102x hubert kalbacher related subjects fas agonist m33 article li european economic area tcr-mimic antibody antigen-specific conditions privacy policy thomas halder medical research cho cells cotransfected tübingen medical school check access instant access cell response hla-drb10401 accepting optional cookies claudia müller isolated drb10401 molecules immunotherapy aims specific sensitization article log journal finder publish august 1998 volume 47 susanne heinzel fas ligand synthetic peptides article cite human molecules melanoma cells fm3 cells privacy policy personal data

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Tumour-specific MHC-class-II-restricted responses after in vitro sensitization to synthetic peptides corresponding to gp100 and Annexin II eluted from melanoma cells
         description: In a search for potentially tumour-specific MHC-class-II-restricted antigens, the immunogenicity of endogenous peptides that had been eluted from HLA-DR molecules of the human melanoma cell line FM3 (HLA-DRB1*02x, DRB1*0401) was tested in vitro. Two 16-mers representing gp100 positions 44–59, and annexin II positions 208–223 bound well to isolated DRB1*0401 molecules and are discussed here. HLA-DR-matched normal donors' T cells were cultured with peptide-pulsed artificial antigen-presenting cells (CHO cells cotransfected with genes for HLA-DRB1*0401 and CD80 and coexpressing high levels of both human molecules). Specific sensitization was achieved against both peptides, as measured in assays of autocrine proliferation and interleukin-2 secretion. Moreover, responses to native autologous melanoma cells but not to autologous B cells were also observed. In view of the expression of fas by the activated T cells and of fas ligand by the melanoma cells, blockade of potential fas/fas-ligand interactions was undertaken using monoclonal antibodies (mAb). The antagonistic fas-specific mAb M3, but not the fas agonist M33, caused a markedly enhanced T cell response to FM3 cells. These results demonstrate that synthetic peptide antigens are able to sensitize T cells in vitro for effective MHC-class-II-restricted recognition of melanoma cells.
         datePublished:
         dateModified:
         pageStart:32
         pageEnd:38
         sameAs:https://doi.org/10.1007/s002620050501
         keywords:
            Key words HLA-DR-restricted tumour antigens
            Synthetic peptide antigens
            Tumour escape from immune responses
            Apoptosis
            Melanoma
            Oncology
            Immunology
            Cancer Research
         image:
         isPartOf:
            name:Cancer Immunology, Immunotherapy
            issn:
               1432-0851
               0340-7004
            volumeNumber:47
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer-Verlag
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Kun Li
               affiliation:
                     name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany
                     address:
                        name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany, , DE
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Medi Adibzadeh
               affiliation:
                     name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany
                     address:
                        name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Thomas Halder
               affiliation:
                     name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany
                     address:
                        name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany, , DE
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Hubert Kalbacher
               affiliation:
                     name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany
                     address:
                        name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany, , DE
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Susanne Heinzel
               affiliation:
                     name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany
                     address:
                        name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Claudia Müller
               affiliation:
                     name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany
                     address:
                        name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany, , DE
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Jesper Zeuthen
               affiliation:
                     name:Danish Cancer Society, Copenhagen, Denmark
                     address:
                        name:Danish Cancer Society, Copenhagen, Denmark, , DK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Graham Pawelec
               affiliation:
                     name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany
                     address:
                        name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Tumour-specific MHC-class-II-restricted responses after in vitro sensitization to synthetic peptides corresponding to gp100 and Annexin II eluted from melanoma cells
      description: In a search for potentially tumour-specific MHC-class-II-restricted antigens, the immunogenicity of endogenous peptides that had been eluted from HLA-DR molecules of the human melanoma cell line FM3 (HLA-DRB1*02x, DRB1*0401) was tested in vitro. Two 16-mers representing gp100 positions 44–59, and annexin II positions 208–223 bound well to isolated DRB1*0401 molecules and are discussed here. HLA-DR-matched normal donors' T cells were cultured with peptide-pulsed artificial antigen-presenting cells (CHO cells cotransfected with genes for HLA-DRB1*0401 and CD80 and coexpressing high levels of both human molecules). Specific sensitization was achieved against both peptides, as measured in assays of autocrine proliferation and interleukin-2 secretion. Moreover, responses to native autologous melanoma cells but not to autologous B cells were also observed. In view of the expression of fas by the activated T cells and of fas ligand by the melanoma cells, blockade of potential fas/fas-ligand interactions was undertaken using monoclonal antibodies (mAb). The antagonistic fas-specific mAb M3, but not the fas agonist M33, caused a markedly enhanced T cell response to FM3 cells. These results demonstrate that synthetic peptide antigens are able to sensitize T cells in vitro for effective MHC-class-II-restricted recognition of melanoma cells.
      datePublished:
      dateModified:
      pageStart:32
      pageEnd:38
      sameAs:https://doi.org/10.1007/s002620050501
      keywords:
         Key words HLA-DR-restricted tumour antigens
         Synthetic peptide antigens
         Tumour escape from immune responses
         Apoptosis
         Melanoma
         Oncology
         Immunology
         Cancer Research
      image:
      isPartOf:
         name:Cancer Immunology, Immunotherapy
         issn:
            1432-0851
            0340-7004
         volumeNumber:47
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer-Verlag
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Kun Li
            affiliation:
                  name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany
                  address:
                     name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany, , DE
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Medi Adibzadeh
            affiliation:
                  name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany
                  address:
                     name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Thomas Halder
            affiliation:
                  name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany
                  address:
                     name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany, , DE
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Hubert Kalbacher
            affiliation:
                  name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany
                  address:
                     name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany, , DE
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Susanne Heinzel
            affiliation:
                  name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany
                  address:
                     name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Claudia Müller
            affiliation:
                  name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany
                  address:
                     name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany, , DE
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jesper Zeuthen
            affiliation:
                  name:Danish Cancer Society, Copenhagen, Denmark
                  address:
                     name:Danish Cancer Society, Copenhagen, Denmark, , DK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Graham Pawelec
            affiliation:
                  name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany
                  address:
                     name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Cancer Immunology, Immunotherapy
      issn:
         1432-0851
         0340-7004
      volumeNumber:47
Organization:
      name:Springer-Verlag
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany
      address:
         name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany, , DE
         type:PostalAddress
      name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany
      address:
         name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
         type:PostalAddress
      name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany
      address:
         name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany, , DE
         type:PostalAddress
      name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany
      address:
         name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany, , DE
         type:PostalAddress
      name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany
      address:
         name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
         type:PostalAddress
      name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany
      address:
         name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany, , DE
         type:PostalAddress
      name:Danish Cancer Society, Copenhagen, Denmark
      address:
         name:Danish Cancer Society, Copenhagen, Denmark, , DK
         type:PostalAddress
      name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany
      address:
         name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Kun Li
      affiliation:
            name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany
            address:
               name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany, , DE
               type:PostalAddress
            type:Organization
      name:Medi Adibzadeh
      affiliation:
            name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany
            address:
               name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
               type:PostalAddress
            type:Organization
      name:Thomas Halder
      affiliation:
            name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany
            address:
               name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany, , DE
               type:PostalAddress
            type:Organization
      name:Hubert Kalbacher
      affiliation:
            name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany
            address:
               name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany, , DE
               type:PostalAddress
            type:Organization
      name:Susanne Heinzel
      affiliation:
            name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany
            address:
               name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
               type:PostalAddress
            type:Organization
      name:Claudia Müller
      affiliation:
            name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany
            address:
               name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany, , DE
               type:PostalAddress
            type:Organization
      name:Jesper Zeuthen
      affiliation:
            name:Danish Cancer Society, Copenhagen, Denmark
            address:
               name:Danish Cancer Society, Copenhagen, Denmark, , DK
               type:PostalAddress
            type:Organization
      name:Graham Pawelec
      affiliation:
            name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany
            address:
               name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany, , DE
      name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
      name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany, , DE
      name:Medical and Natural Sciences Research Center, University of Tübingen, Tübingen, Germany, , DE
      name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
      name:Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany, , DE
      name:Danish Cancer Society, Copenhagen, Denmark, , DK
      name:Tübingen Ageing and Tumour Immunology Group, University of Tübingen Center for Medical Research, Derendingen, Tübingen, Germany, , DE
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(39)

• How much cash flow does https://www.springernature.com/gp/authors have monthly?
• Find out how much https://link.springernature.com/home/ earns monthly
• How much income is https://order.springer.com/public/cart earning monthly?
• Profit of https://submission.nature.com/new-submission/262/3
• How much does https://www.springernature.com/gp/librarians/licensing/agc/journals generate monthly?
• Learn how profitable https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Kun%20Li is on a monthly basis
• What's the monthly money flow for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Kun%20Li%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Medi%20Adibzadeh bring in each month?
• How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Medi%20Adibzadeh%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
• Earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Thomas%20Halder
• Discover the revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Thomas%20Halder%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Hubert%20Kalbacher pull in monthly?
• Revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Hubert%20Kalbacher%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Susanne%20Heinzel's total income per month
• What is the monthly revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Susanne%20Heinzel%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Claudia%20M%C3%BCller's total income per month
• See how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Claudia%20M%C3%BCller%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en makes per month
• Check the income stats for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jesper%20Zeuthen
• Earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jesper%20Zeuthen%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What's the income generated by https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Graham%20Pawelec each month?
• Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Graham%20Pawelec%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
• How much profit does https://s100.copyright.com/AppDispatchServlet?title=Tumour-specific%20MHC-class-II-restricted%20responses%20after%20in%20vitro%20sensitization%20to%20synthetic%20peptides%20corresponding%20to%20gp100%20and%20Annexin%20II%20eluted%20from%20melanoma%20cells&author=Kun%20Li%20et%20al&contentID=10.1007%2Fs002620050501©right=Springer-Verlag%20Berlin%20Heidelberg&publication=0340-7004&publicationDate=1998-08&publisherName=SpringerNature&orderBeanReset=true make?
• Earnings of https://citation-needed.springer.com/v2/references/10.1007/s002620050501?format=refman&flavour=citation
• What is the monthly revenue of https://authorservices.springernature.com/go/sn/?utm_source=SNLinkfooter&utm_medium=Web&utm_campaign=SNReferral?
• What are the earnings of https://www.springernature.com/gp/open-research/about/the-fundamentals-of-open-access-and-open-research?
• How much does https://www.springernature.com/gp/products gross monthly?
• What's the income of https://www.springernature.com/gp/librarians?
• What is the monthly revenue of https://www.springernature.com/gp/societies?
• How much does https://www.springernature.com/gp/partners earn?
• Explore the financials of https://www.springer.com/
• What's the income generated by https://www.nature.com/ each month?
• Monthly income for https://www.biomedcentral.com/
• How much profit is https://www.palgrave.com/ making per month?
• How much money does https://www.apress.com/ generate?
• What's the income generated by https://www.springernature.com/gp/legal/ccpa each month?
• How much does https://www.springernature.com/gp/info/accessibility make?
• How much does https://support.springernature.com/en/support/home make?
• Explore the financials of https://support.springernature.com/en/support/solutions/articles/6000255911-subscription-cancellations
• What's the financial intake of https://www.springernature.com/?

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Clipboard.js
• Prism.js

CDN Services {📦}

• Crossref