We are analyzing https://link.springer.com/article/10.1007/s00253-015-6910-9.

Title:
CYP287A1 is a carotenoid 2-β-hydroxylase required for deinoxanthin biosynthesis in Deinococcus radiodurans R1 | Applied Microbiology and Biotechnology
Description:
The carotenoid deinoxanthin is a crucial resistance factor against various stresses in the radiation-resistant bacterium Deinococcus radiodurans. Disruption of the gene dr2473 encoding the cytochrome P450 CYP287A1 led to the accumulation of 2-deoxydeinoxanthin in D. radiodurans, demonstrating that CYP287A1 is a novel β-carotene 2-hydroxylase. The dr2473 knockout mutant was shown to be more sensitive to UV radiation and oxidative stress than the wild-type strain D. radiodurans R1, indicating that the C2 alcohol of deinoxanthin is important for antioxidant activity.
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Keywords {🔍}

article, pubmed, google, scholar, cas, radiodurans, deinococcus, carotenoid, biosynthesis, microbiol, national, china, research, hydroxylase, cypa, zhang, molnár, biol, deinoxanthin, bacterium, gene, cytochrome, privacy, cookies, content, zhou, wei, access, wang, appl, dois, science, information, publish, search, biotechnology, lin, istván, resistance, radiation, stress, biotechnol, rev, plant, mol, products, radioresistant, central, tian, sun,

Topics {✒️}

carotenoid 2-β-hydroxylase required month download article/chapter cytochrome-p450 hydroxylase involved extremophilic deinococcus-thermus bacteria extreme radiation resistance β-carotene 2-hydroxylase cytochrome p450 hydroxylase related subjects article applied microbiology dna repair-deficient mutant deinococcus radiodurans r1 istván molnár author information authors beta-carotene hydroxylase full article pdf stress-related genes privacy choices/manage cookies aseptically manufactured products xanthophyllomyces dendrorhous encodes enhances salt tolerance radiation kills cells enhances uv tolerance check access instant access cytochrome p450 gene dr2473 encoding national basic research deinococcus radiodurans deinococcus radiodurans thermus thermophilus hb27 bacterial aldoxime dehydratase national science foundation european economic area pprm decreases resistance retzius nerve cells leech haemopis sanguisuga cyanide-free production dna damage analyses cyclooligomer depsipeptide beauvericin increases intercellular connections national high-tech electronic supplementary material article zhou conditions privacy policy oxidative stress resistance molecular biotechnology published crucial resistance factor dr2473 knockout mutant wild-type strain radiodurans r1

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