We are analyzing https://link.springer.com/article/10.1007/s00125-006-0300-x.

Title:
Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n−3 polyunsaturated fatty acids | Diabetologia
Description:
Aims/hypothesis Inflammatory alterations in white adipose tissue appear to underlie complications of obesity including diabetes mellitus. Polyunsaturated fatty acids (PUFA), particularly those of the n−3 series, modulate immune responses and may ameliorate insulin sensitivity. In this study, we investigated how PUFA affect white adipose tissue inflammation and gene expression in obese diabetic animals. Materials and methods We treated db/db mice as well as lean non-diabetic mice (db/+) with either low-fat standard diet (LF) or high-fat diets rich in (1) saturated/monounsaturated fatty acids (HF/S), (2) n−6 PUFA (HF/6) and (3) the latter including purified marine n−3 PUFA (HF/3). Results Many genes involved in inflammatory alterations were upregulated in db/db mice on HF/S compared with LF in parallel with phosphorylation of c-Jun N-terminal kinase (JNK). In parallel, adipose tissue infiltration with macrophages was markedly enhanced by HF/S. When compared with HF/S, HF/6 showed only marginal effects on adipose tissue inflammation. However, inclusion of n−3 PUFA in the diet (HF/3) completely prevented macrophage infiltration induced by high-fat diet and changes in inflammatory gene expression, also tending to reduce JNK phosphorylation (p<0.1) in diabetic mice despite unreduced body weight. Moreover, high-fat diets (HF/S, HF/6) downregulated expression and reduced serum concentrations of adiponectin, but this was not the case with n−3 PUFA. Conclusions/interpretation n−3 PUFA prevent adipose tissue inflammation induced by high-fat diet in obese diabetic mice, thereby dissecting obesity from adipose tissue inflammation. These data suggest that beneficial effects of n−3 PUFA on diabetes development could be mediated by their effect on adipose tissue inflammation.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Health & Fitness
Education
Science

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We see no obvious way the site makes money.

Some websites aren't about earning revenue; they're built to connect communities or raise awareness. There are numerous motivations behind creating websites. This might be one of them. Link.springer.com could be secretly minting cash, but we can't detect the process.

Keywords {🔍}

pufa, tissue, adipose, expression, mice, highfat, article, pubmed, google, scholar, fatty, gene, cas, dbdb, hfs, inflammatory, diet, acids, inflammation, animals, macrophage, obese, insulin, diets, obesity, diabetes, fig, effects, fed, compared, data, white, genes, effect, jnk, alterations, diabetic, polyunsaturated, adiponectin, usa, including, acid, macrophages, resistance, bars, induced, sensitivity, infiltration, dietary, metabolic,

Topics {✒️}

c-jun n-terminal kinase long-chain marine high-fat diet-induced downregulation quantitative real-time rt-pcr blood-glucose-lowering drugs metformin specific anti-inflammatory properties macrophage-secreted factor cachectin n3-polyunsaturated fatty acids long-term supplementation tumor necrosis factor-alpha adipose tissue-derived hormones mice lacking adiponectin/acrp30 quantitative real-time pcr real-time rt-pcr detergent-insoluble membrane domains prevent hf/s-induced adipocyte-derived hormone adiponectin insulin-sensitising adipokine adiponectin links inflammatory pathways fish-oil supplementation anti-inflammatory cytokine high-fat diet effects adipose-tissue-infiltrating macrophages [20] adipose tissue-resident macrophages high-fat diet rich insulin-stimulated glucose disposal diet-induced insulin resistance saturated/monounsaturated fatty acids high-fat diet abrogated high-fat diet selectively low-fat standard diet alexa488-labelled f4/80 antibody polyunsaturated fatty acids chronic low-grade inflammation inflammatory pathways interfering high-fat diets rich high-fat diets enriched treated db/db mice anti-inflammatory action obese diabetic db/db db/db mice resulted dietary fatty acids fish oil preparations db/+ lf-diet mice obesity-related insulin resistance monounsaturated fatty acids anti-inflammatory effects typical macrophage-rich tissues profiling gene transcription basic research institute

Questions {❓}

Franks PW, Luan J, Browne PO et al (2004) Does peroxisome proliferator-activated receptor gamma genotype (Pro12ala) modify the association of physical activity and dietary fat with fasting insulin level?
Pradhan AD, Ridker PM (2002) Do atherosclerosis and type 2 diabetes share a common inflammatory basis?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n−3 polyunsaturated fatty acids
         description:Inflammatory alterations in white adipose tissue appear to underlie complications of obesity including diabetes mellitus. Polyunsaturated fatty acids (PUFA), particularly those of the n−3 series, modulate immune responses and may ameliorate insulin sensitivity. In this study, we investigated how PUFA affect white adipose tissue inflammation and gene expression in obese diabetic animals. We treated db/db mice as well as lean non-diabetic mice (db/+) with either low-fat standard diet (LF) or high-fat diets rich in (1) saturated/monounsaturated fatty acids (HF/S), (2) n−6 PUFA (HF/6) and (3) the latter including purified marine n−3 PUFA (HF/3). Many genes involved in inflammatory alterations were upregulated in db/db mice on HF/S compared with LF in parallel with phosphorylation of c-Jun N-terminal kinase (JNK). In parallel, adipose tissue infiltration with macrophages was markedly enhanced by HF/S. When compared with HF/S, HF/6 showed only marginal effects on adipose tissue inflammation. However, inclusion of n−3 PUFA in the diet (HF/3) completely prevented macrophage infiltration induced by high-fat diet and changes in inflammatory gene expression, also tending to reduce JNK phosphorylation (p<0.1) in diabetic mice despite unreduced body weight. Moreover, high-fat diets (HF/S, HF/6) downregulated expression and reduced serum concentrations of adiponectin, but this was not the case with n−3 PUFA. n−3 PUFA prevent adipose tissue inflammation induced by high-fat diet in obese diabetic mice, thereby dissecting obesity from adipose tissue inflammation. These data suggest that beneficial effects of n−3 PUFA on diabetes development could be mediated by their effect on adipose tissue inflammation.
         datePublished:2006-06-17T00:00:00Z
         dateModified:2006-06-17T00:00:00Z
         pageStart:2109
         pageEnd:2119
         sameAs:https://doi.org/10.1007/s00125-006-0300-x
         keywords:
            Adiponectin
            Adipose tissue
            Diabetes mellitus
            Fish oil
            Inflammation
            Macrophages
            Obesity
            Polyunsaturated fatty acids
            Internal Medicine
            Metabolic Diseases
            Human Physiology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig3_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig4_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig5_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig6_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig7_HTML.gif
         isPartOf:
            name:Diabetologia
            issn:
               1432-0428
               0012-186X
            volumeNumber:49
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer-Verlag
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:J. Todoric
               affiliation:
                     name:Medical University of Vienna
                     address:
                        name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
                        type:PostalAddress
                     type:Organization
                     name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
                     address:
                        name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
                        type:PostalAddress
                     type:Organization
               type:Person
               name:M. Löffler
               affiliation:
                     name:Medical University of Vienna
                     address:
                        name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
                        type:PostalAddress
                     type:Organization
                     name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
                     address:
                        name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
                        type:PostalAddress
                     type:Organization
               type:Person
               name:J. Huber
               affiliation:
                     name:Medical University of Vienna
                     address:
                        name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
                        type:PostalAddress
                     type:Organization
               type:Person
               name:M. Bilban
               affiliation:
                     name:Medical University of Vienna and Ludwig Boltzmann Institute for Clinical and Experimental Oncology
                     address:
                        name:Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna and Ludwig Boltzmann Institute for Clinical and Experimental Oncology, Vienna, Austria
                        type:PostalAddress
                     type:Organization
               type:Person
               name:M. Reimers
               affiliation:
                     name:National Cancer Institute
                     address:
                        name:Laboratory of Molecular Pharmacology, National Cancer Institute, Bethesda, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:A. Kadl
               affiliation:
                     name:University of Virginia
                     address:
                        name:Cardiovascular Research Center and Department of Pharmacology, University of Virginia, Charlottesville, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:M. Zeyda
               affiliation:
                     name:Medical University of Vienna
                     address:
                        name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
                        type:PostalAddress
                     type:Organization
               type:Person
               name:W. Waldhäusl
               affiliation:
                     name:Medical University of Vienna
                     address:
                        name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
                        type:PostalAddress
                     type:Organization
                     name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
                     address:
                        name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
                        type:PostalAddress
                     type:Organization
               type:Person
               name:T. M. Stulnig
               affiliation:
                     name:Medical University of Vienna
                     address:
                        name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
                        type:PostalAddress
                     type:Organization
                     name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
                     address:
                        name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:1
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n−3 polyunsaturated fatty acids
      description:Inflammatory alterations in white adipose tissue appear to underlie complications of obesity including diabetes mellitus. Polyunsaturated fatty acids (PUFA), particularly those of the n−3 series, modulate immune responses and may ameliorate insulin sensitivity. In this study, we investigated how PUFA affect white adipose tissue inflammation and gene expression in obese diabetic animals. We treated db/db mice as well as lean non-diabetic mice (db/+) with either low-fat standard diet (LF) or high-fat diets rich in (1) saturated/monounsaturated fatty acids (HF/S), (2) n−6 PUFA (HF/6) and (3) the latter including purified marine n−3 PUFA (HF/3). Many genes involved in inflammatory alterations were upregulated in db/db mice on HF/S compared with LF in parallel with phosphorylation of c-Jun N-terminal kinase (JNK). In parallel, adipose tissue infiltration with macrophages was markedly enhanced by HF/S. When compared with HF/S, HF/6 showed only marginal effects on adipose tissue inflammation. However, inclusion of n−3 PUFA in the diet (HF/3) completely prevented macrophage infiltration induced by high-fat diet and changes in inflammatory gene expression, also tending to reduce JNK phosphorylation (p<0.1) in diabetic mice despite unreduced body weight. Moreover, high-fat diets (HF/S, HF/6) downregulated expression and reduced serum concentrations of adiponectin, but this was not the case with n−3 PUFA. n−3 PUFA prevent adipose tissue inflammation induced by high-fat diet in obese diabetic mice, thereby dissecting obesity from adipose tissue inflammation. These data suggest that beneficial effects of n−3 PUFA on diabetes development could be mediated by their effect on adipose tissue inflammation.
      datePublished:2006-06-17T00:00:00Z
      dateModified:2006-06-17T00:00:00Z
      pageStart:2109
      pageEnd:2119
      sameAs:https://doi.org/10.1007/s00125-006-0300-x
      keywords:
         Adiponectin
         Adipose tissue
         Diabetes mellitus
         Fish oil
         Inflammation
         Macrophages
         Obesity
         Polyunsaturated fatty acids
         Internal Medicine
         Metabolic Diseases
         Human Physiology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig3_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig4_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig5_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig6_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00125-006-0300-x/MediaObjects/125_2006_300_Fig7_HTML.gif
      isPartOf:
         name:Diabetologia
         issn:
            1432-0428
            0012-186X
         volumeNumber:49
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer-Verlag
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:J. Todoric
            affiliation:
                  name:Medical University of Vienna
                  address:
                     name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
                     type:PostalAddress
                  type:Organization
                  name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
                  address:
                     name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
                     type:PostalAddress
                  type:Organization
            type:Person
            name:M. Löffler
            affiliation:
                  name:Medical University of Vienna
                  address:
                     name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
                     type:PostalAddress
                  type:Organization
                  name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
                  address:
                     name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
                     type:PostalAddress
                  type:Organization
            type:Person
            name:J. Huber
            affiliation:
                  name:Medical University of Vienna
                  address:
                     name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
                     type:PostalAddress
                  type:Organization
            type:Person
            name:M. Bilban
            affiliation:
                  name:Medical University of Vienna and Ludwig Boltzmann Institute for Clinical and Experimental Oncology
                  address:
                     name:Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna and Ludwig Boltzmann Institute for Clinical and Experimental Oncology, Vienna, Austria
                     type:PostalAddress
                  type:Organization
            type:Person
            name:M. Reimers
            affiliation:
                  name:National Cancer Institute
                  address:
                     name:Laboratory of Molecular Pharmacology, National Cancer Institute, Bethesda, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:A. Kadl
            affiliation:
                  name:University of Virginia
                  address:
                     name:Cardiovascular Research Center and Department of Pharmacology, University of Virginia, Charlottesville, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:M. Zeyda
            affiliation:
                  name:Medical University of Vienna
                  address:
                     name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
                     type:PostalAddress
                  type:Organization
            type:Person
            name:W. Waldhäusl
            affiliation:
                  name:Medical University of Vienna
                  address:
                     name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
                     type:PostalAddress
                  type:Organization
                  name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
                  address:
                     name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
                     type:PostalAddress
                  type:Organization
            type:Person
            name:T. M. Stulnig
            affiliation:
                  name:Medical University of Vienna
                  address:
                     name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
                     type:PostalAddress
                  type:Organization
                  name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
                  address:
                     name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:1
["Periodical","PublicationVolume"]:
      name:Diabetologia
      issn:
         1432-0428
         0012-186X
      volumeNumber:49
Organization:
      name:Springer-Verlag
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Medical University of Vienna
      address:
         name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
         type:PostalAddress
      name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
      address:
         name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
         type:PostalAddress
      name:Medical University of Vienna
      address:
         name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
         type:PostalAddress
      name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
      address:
         name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
         type:PostalAddress
      name:Medical University of Vienna
      address:
         name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
         type:PostalAddress
      name:Medical University of Vienna and Ludwig Boltzmann Institute for Clinical and Experimental Oncology
      address:
         name:Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna and Ludwig Boltzmann Institute for Clinical and Experimental Oncology, Vienna, Austria
         type:PostalAddress
      name:National Cancer Institute
      address:
         name:Laboratory of Molecular Pharmacology, National Cancer Institute, Bethesda, USA
         type:PostalAddress
      name:University of Virginia
      address:
         name:Cardiovascular Research Center and Department of Pharmacology, University of Virginia, Charlottesville, USA
         type:PostalAddress
      name:Medical University of Vienna
      address:
         name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
         type:PostalAddress
      name:Medical University of Vienna
      address:
         name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
         type:PostalAddress
      name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
      address:
         name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
         type:PostalAddress
      name:Medical University of Vienna
      address:
         name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
         type:PostalAddress
      name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
      address:
         name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:J. Todoric
      affiliation:
            name:Medical University of Vienna
            address:
               name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
               type:PostalAddress
            type:Organization
            name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
            address:
               name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
               type:PostalAddress
            type:Organization
      name:M. Löffler
      affiliation:
            name:Medical University of Vienna
            address:
               name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
               type:PostalAddress
            type:Organization
            name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
            address:
               name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
               type:PostalAddress
            type:Organization
      name:J. Huber
      affiliation:
            name:Medical University of Vienna
            address:
               name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
               type:PostalAddress
            type:Organization
      name:M. Bilban
      affiliation:
            name:Medical University of Vienna and Ludwig Boltzmann Institute for Clinical and Experimental Oncology
            address:
               name:Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna and Ludwig Boltzmann Institute for Clinical and Experimental Oncology, Vienna, Austria
               type:PostalAddress
            type:Organization
      name:M. Reimers
      affiliation:
            name:National Cancer Institute
            address:
               name:Laboratory of Molecular Pharmacology, National Cancer Institute, Bethesda, USA
               type:PostalAddress
            type:Organization
      name:A. Kadl
      affiliation:
            name:University of Virginia
            address:
               name:Cardiovascular Research Center and Department of Pharmacology, University of Virginia, Charlottesville, USA
               type:PostalAddress
            type:Organization
      name:M. Zeyda
      affiliation:
            name:Medical University of Vienna
            address:
               name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
               type:PostalAddress
            type:Organization
      name:W. Waldhäusl
      affiliation:
            name:Medical University of Vienna
            address:
               name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
               type:PostalAddress
            type:Organization
            name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
            address:
               name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
               type:PostalAddress
            type:Organization
      name:T. M. Stulnig
      affiliation:
            name:Medical University of Vienna
            address:
               name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
               type:PostalAddress
            type:Organization
            name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences)
            address:
               name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
      name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
      name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
      name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
      name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
      name:Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna and Ludwig Boltzmann Institute for Clinical and Experimental Oncology, Vienna, Austria
      name:Laboratory of Molecular Pharmacology, National Cancer Institute, Bethesda, USA
      name:Cardiovascular Research Center and Department of Pharmacology, University of Virginia, Charlottesville, USA
      name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
      name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
      name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria
      name:Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
      name:CeMM (Center of Molecular Medicine of the Austrian Academy of Sciences), Vienna, Austria

External Links {🔗}(180)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.71s.

LINK . SPRINGER . COM {}