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Title:
Ras effectors and their role in mitogenesis and oncogenesis | Journal of Molecular Medicine
Description:
Ras proteins are membrane-bound GTP-binding proteins that play a critical role in the control of cell growth. Through a large number of genetic and biochemical studies it is becoming increasingly evident that the biological activity of Ras proteins is mediated by multiple signaling pathways. This review provides an account of the target proteins that interact with Ras and the functional consequences of these interactions. The relative contribution of the different Ras effector pathways to the mitogenic and oncogenic effects of Ras are discussed.
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Keywords {🔍}

article, ras, proteins, privacy, cookies, content, journal, information, publish, search, effectors, role, access, data, log, research, molecular, mitogenesis, joneson, barsagi, discover, springer, optional, personal, parties, policy, find, track, medicine, oncogenesis, review, cite, explore, gtpbinding, growth, activity, signaling, pathways, institution, chapter, related, subjects, oncogene, author, state, stony, brook, usa, rights, permissions,

Topics {✒️}

membrane-bound gtp-binding proteins month download article/chapter ras proteins cell growth privacy choices/manage cookies molecular medicine aims target proteins full article pdf ras effector pathways ras/rap gtpases european economic area scope submit manuscript post translational modifications related subjects conditions privacy policy bar-sagi multiple signaling pathways ras effectors accepting optional cookies journal finder publish main content log check access instant access article journal information state university privacy policy personal data article log books a molecular genetics article cite optional cookies manage preferences article joneson journal publish data protection essential cookies cookies skip subscription content similar content ral signaling effectors institution subscribe usage analysis social media varying standards mitogenesis august 1997 volume 75 large number

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