We are analyzing https://link.springer.com/article/10.1007/s00018-014-1817-7.

Title:
Mammary lineage tracing: the coming of age | Cellular and Molecular Life Sciences
Description:
Identification and characterization of the normal epithelial lineages in the mammary gland is a fundamental step in understanding both development and cellular origin of cancer. In contrast to other tissues where lineage tracing has been widely accepted as a method of choice for dissecting the stem cell hierarchy, mammary gland has long remained a challenge due to its unique developmental and topological features. Recent advances in high-resolution single-cell imaging, combined with the use of inducible Cre-recombinase and in situ cell ablation, have provided unprecedented insight into mammary epithelial cell composition and function. Here, we briefly summarize and compare different mammary gland lineage tracing strategies, examine associated caveats and discuss future challenges and opportunities.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Education
Telecommunications
Science

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 7,642,828 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We don't see any clear sign of profit-making.

Not every website is profit-driven; some are created to spread information or serve as an online presence. Websites can be made for many reasons. This could be one of them. Link.springer.com has a revenue plan, but it's either invisible or we haven't found it.

Keywords {🔍}

mammary, article, pubmed, google, scholar, cell, cas, stem, cells, gland, cancer, epithelial, breast, central, lineage, mouse, res, nature, biol, cellular, tracing, developmental, access, stingl, van, privacy, cookies, content, sale, development, bcr, publish, search, life, identification, lineages, hierarchy, expression, human, fate, smith, functional, visvader, eirew, kendrick, smalley, activity, prater, luminal, analysis,

Topics {✒️}

wnt/beta-catenin-responsive stem cells cell-type-specific cre-expressing adenoviruses high-resolution single-cell imaging month download article/chapter single stem cell developmental stage-specific contribution related subjects luminal epithelial lineages full article pdf mammary stem cells multipotent mammary progenitor mammary epithelial cells mouse mammary gland normal epithelial lineages regan jl bipotent stem cells luminal cell hierarchy mammary lineage tracing article sale postnatal mammary gland pregnancy-specific activity privacy choices/manage cookies van kappel ec sanja sale lgr5-expressing cells mammary gland epithelium stem cell hierarchy human breast cancer functional mammary gland inducible cre-recombinase estrogen receptor expression single cell situ cell ablation targeted cell ablation gene expression signatures developmental lineage relationships distinct cellular progenitors cell size enriches mammary cellular hierarchy mammary gland development article cellular european economic area provided unprecedented insight discuss future challenges asselin-labat ml van bragt mp zeng ya stem cells 31 check access instant access

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Mammary lineage tracing: the coming of age
         description:Identification and characterization of the normal epithelial lineages in the mammary gland is a fundamental step in understanding both development and cellular origin of cancer. In contrast to other tissues where lineage tracing has been widely accepted as a method of choice for dissecting the stem cell hierarchy, mammary gland has long remained a challenge due to its unique developmental and topological features. Recent advances in high-resolution single-cell imaging, combined with the use of inducible Cre-recombinase and in situ cell ablation, have provided unprecedented insight into mammary epithelial cell composition and function. Here, we briefly summarize and compare different mammary gland lineage tracing strategies, examine associated caveats and discuss future challenges and opportunities.
         datePublished:2015-01-07T00:00:00Z
         dateModified:2015-01-07T00:00:00Z
         pageStart:1577
         pageEnd:1583
         sameAs:https://doi.org/10.1007/s00018-014-1817-7
         keywords:
            Breast
            Lineages
            Fate mapping
            In situ cell ablation
            Cell-of-origin
            Genetically engineered mouse models
            Topological context
            Cell Biology
            Biomedicine
            general
            Life Sciences
            Biochemistry
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00018-014-1817-7/MediaObjects/18_2014_1817_Fig1_HTML.gif
         isPartOf:
            name:Cellular and Molecular Life Sciences
            issn:
               1420-9071
               1420-682X
            volumeNumber:72
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer Basel
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Sanja Sale
               affiliation:
                     name:University of Rijeka
                     address:
                        name:Department of Biotechnology, University of Rijeka, Rijeka, Croatia
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Kresimir Pavelic
               affiliation:
                     name:University of Rijeka
                     address:
                        name:Department of Biotechnology, University of Rijeka, Rijeka, Croatia
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Mammary lineage tracing: the coming of age
      description:Identification and characterization of the normal epithelial lineages in the mammary gland is a fundamental step in understanding both development and cellular origin of cancer. In contrast to other tissues where lineage tracing has been widely accepted as a method of choice for dissecting the stem cell hierarchy, mammary gland has long remained a challenge due to its unique developmental and topological features. Recent advances in high-resolution single-cell imaging, combined with the use of inducible Cre-recombinase and in situ cell ablation, have provided unprecedented insight into mammary epithelial cell composition and function. Here, we briefly summarize and compare different mammary gland lineage tracing strategies, examine associated caveats and discuss future challenges and opportunities.
      datePublished:2015-01-07T00:00:00Z
      dateModified:2015-01-07T00:00:00Z
      pageStart:1577
      pageEnd:1583
      sameAs:https://doi.org/10.1007/s00018-014-1817-7
      keywords:
         Breast
         Lineages
         Fate mapping
         In situ cell ablation
         Cell-of-origin
         Genetically engineered mouse models
         Topological context
         Cell Biology
         Biomedicine
         general
         Life Sciences
         Biochemistry
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00018-014-1817-7/MediaObjects/18_2014_1817_Fig1_HTML.gif
      isPartOf:
         name:Cellular and Molecular Life Sciences
         issn:
            1420-9071
            1420-682X
         volumeNumber:72
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer Basel
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Sanja Sale
            affiliation:
                  name:University of Rijeka
                  address:
                     name:Department of Biotechnology, University of Rijeka, Rijeka, Croatia
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Kresimir Pavelic
            affiliation:
                  name:University of Rijeka
                  address:
                     name:Department of Biotechnology, University of Rijeka, Rijeka, Croatia
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Cellular and Molecular Life Sciences
      issn:
         1420-9071
         1420-682X
      volumeNumber:72
Organization:
      name:Springer Basel
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Rijeka
      address:
         name:Department of Biotechnology, University of Rijeka, Rijeka, Croatia
         type:PostalAddress
      name:University of Rijeka
      address:
         name:Department of Biotechnology, University of Rijeka, Rijeka, Croatia
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Sanja Sale
      affiliation:
            name:University of Rijeka
            address:
               name:Department of Biotechnology, University of Rijeka, Rijeka, Croatia
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Kresimir Pavelic
      affiliation:
            name:University of Rijeka
            address:
               name:Department of Biotechnology, University of Rijeka, Rijeka, Croatia
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Department of Biotechnology, University of Rijeka, Rijeka, Croatia
      name:Department of Biotechnology, University of Rijeka, Rijeka, Croatia
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(135)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

3.94s.

LINK . SPRINGER . COM {}