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Title:
The complexity of mitogen-activated protein kinases (MAPKs) made simple | Cellular and Molecular Life Sciences
Description:
The mitogen-activated protein kinase (MAPK) pathways are known to be involved in various processes of growth, differentiation and cell death. In spite of their ubiquitous presence and seemingly enormous cross-talk with each other, their action is very specific. This review deals with various aspects of the three different MAPK pathways (ERK, p38 and JNK) and how their specificity is brought about.
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headline:The complexity of mitogen-activated protein kinases (MAPKs) made simple
description:The mitogen-activated protein kinase (MAPK) pathways are known to be involved in various processes of growth, differentiation and cell death. In spite of their ubiquitous presence and seemingly enormous cross-talk with each other, their action is very specific. This review deals with various aspects of the three different MAPK pathways (ERK, p38 and JNK) and how their specificity is brought about.
datePublished:2008-08-01T00:00:00Z
dateModified:2008-08-01T00:00:00Z
pageStart:3525
pageEnd:3544
sameAs:https://doi.org/10.1007/s00018-008-8170-7
keywords:
Mitogen-activated protein kinase
activation
phosphorylation
specificity
ERK
p38
JNK
Cell Biology
Biomedicine
general
Life Sciences
Biochemistry
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description:The mitogen-activated protein kinase (MAPK) pathways are known to be involved in various processes of growth, differentiation and cell death. In spite of their ubiquitous presence and seemingly enormous cross-talk with each other, their action is very specific. This review deals with various aspects of the three different MAPK pathways (ERK, p38 and JNK) and how their specificity is brought about.
datePublished:2008-08-01T00:00:00Z
dateModified:2008-08-01T00:00:00Z
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pageEnd:3544
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Mitogen-activated protein kinase
activation
phosphorylation
specificity
ERK
p38
JNK
Cell Biology
Biomedicine
general
Life Sciences
Biochemistry
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