We are analyzing https://link.springer.com/article/10.1007/s00018-005-5532-2.

Title:
Insights into the genetic basis of congenital heart disease | Cellular and Molecular Life Sciences
Description:
Cardiovascular malformations are the most common type of birth defect and result in significant mortality worldwide. The etiology for the majority of these anomalies remains unknown. Advances in the characterization of the molecular pathways critical for normal cardiac development have led to the identification of numerous genes necessary for this complex morphogenetic process. This work has aided the discovery of an increasing number of single genes being implicated as the cause of human cardiovascular malformations. This review summarizes normal cardiac development and outlines the recent discoveries of the genetic causes of congenital heart disease.
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Keywords {🔍}

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Topics {✒️}

congenital heart disease normal cardiac development month download article/chapter human cardiovascular malformations privacy choices/manage cookies related subjects full article pdf molecular pathways critical cardiovascular malformations genetics author correspondence european economic area scope submit manuscript significant mortality worldwide anomalies remains unknown complex morphogenetic process conditions privacy policy accepting optional cookies main content log journal finder publish article cellular 1007/s00018-005-5532-2 keywords check access instant access life sci molecular biology article garg article log privacy policy personal data information books a article cite optional cookies manage preferences data protection essential cookies cookies skip subscription content similar content institution subscribe journal publish usage analysis social media varying standards common type birth defect numerous genes increasing number single genes

Schema {🗺️}

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         description:Cardiovascular malformations are the most common type of birth defect and result in significant mortality worldwide. The etiology for the majority of these anomalies remains unknown. Advances in the characterization of the molecular pathways critical for normal cardiac development have led to the identification of numerous genes necessary for this complex morphogenetic process. This work has aided the discovery of an increasing number of single genes being implicated as the cause of human cardiovascular malformations. This review summarizes normal cardiac development and outlines the recent discoveries of the genetic causes of congenital heart disease.
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