We are analyzing https://link.springer.com/article/10.1007/s00018-005-5188-y.

Title:
Exogenous gangliosides, neuronal plasticity and repair, and the neurotrophins | Cellular and Molecular Life Sciences
Description:
Gangliosides, a heterogeneous family of glycosphingolipids abundant in the brain, have been shown to affect neuronal plasticity during development, adulthood and aging. This review will examine old and recent evidence that exogenous gangliosides and in particular GM1, the prototype member of this family, exhibit multimodal neurotrophic effects. Since these compounds are a potential therapeutic tool for the treatment of various forms of acute or chronic neurodegenerative diseases, understanding the dynamic interplay of gangliosides and neuronal cells is essential in the effort to cure neurological disorders. Focus will be given to the novel and provocative hypothesis that gangliosides’ neuroprotective properties may derive from their ability to mimic endogenous neurotrophic factors.
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Keywords {🔍}

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Topics {✒️}

month download article/chapter affect neuronal plasticity privacy choices/manage cookies full article pdf neural stem cells related subjects european economic area scope submit manuscript potential therapeutic tool chronic neurodegenerative diseases cure neurological disorders conditions privacy policy neuronal plasticity author correspondence gangliosides’ neuroprotective properties accepting optional cookies neuronal cells main content log article cellular journal finder publish neurotrophins review published neuroscience research building life sci article mocchetti check access trk access article log instant access exogenous gangliosides privacy policy personal data article cite books a optional cookies manage preferences data protection cookies skip subscription content similar content information institution subscribe journal publish essential cookies usage analysis social media varying standards glycosphingolipids abundant recent evidence prototype member

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