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Regulation of food intake by oleoylethanolamide | Cellular and Molecular Life Sciences
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Oleoylethanolamide (OEA), the naturally occurring amide of ethanolamine and oleic acid, is an endogenous lipid that modulates feeding, body weight and lipid metabolism by binding with high affinity to the ligand-activated transcription factor, peroxisome proliferator-activated receptor-alpha (PPAR-α). In the present article, we describe the biochemical pathways responsible for the initiation and termination of OEA signaling, and outline the pharmacological properties of this compound in relation to its ability to activate PPAR-α. Finally, we discuss the possible role of OEA as a peripheral satiety hormone.
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article, oleoylethanolamide, access, privacy, cookies, content, lipid, information, publish, search, gaetani, piomelli, pparα, california, data, log, journal, research, life, verme, oea, metabolism, satiety, open, discover, author, university, usa, springer, optional, personal, parties, policy, find, track, cellular, molecular, sciences, regulation, food, intake, cite, oveisi, burton, explore, feeding, factor, peroxisome, proliferatoractivated, receptoralpha,
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peroxisome proliferator-activated receptor-alpha ligand-activated transcription factor month download article/chapter peripheral satiety hormone privacy choices/manage cookies related subjects full article pdf oleoylethanolamide review published european economic area scope submit manuscript naturally occurring amide biochemical pathways responsible fasting blood sugar dietary habits attenuates aβ pathology rome “la sapienza” le aldo moro conditions privacy policy check access instant access accepting optional cookies author correspondence activate ppar-α main content log article cellular lipid metabolism journal finder publish modulates feeding article number 708 present article article log endogenous lipid lipid profile oleoylethanolamide supplementation privacy policy personal data glucose metabolism life sci article cite books a optional cookies manage preferences piomelli center piomelli department lo verme ppar-α data protection essential cookies cookies skip subscription content
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headline:Regulation of food intake by oleoylethanolamide
description:Oleoylethanolamide (OEA), the naturally occurring amide of ethanolamine and oleic acid, is an endogenous lipid that modulates feeding, body weight and lipid metabolism by binding with high affinity to the ligand-activated transcription factor, peroxisome proliferator-activated receptor-alpha (PPAR-α). In the present article, we describe the biochemical pathways responsible for the initiation and termination of OEA signaling, and outline the pharmacological properties of this compound in relation to its ability to activate PPAR-α. Finally, we discuss the possible role of OEA as a peripheral satiety hormone.
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palmitoylethanolamide
peroxisome proliferator-activated receptor-alpha (PPAR-α)
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description:Oleoylethanolamide (OEA), the naturally occurring amide of ethanolamine and oleic acid, is an endogenous lipid that modulates feeding, body weight and lipid metabolism by binding with high affinity to the ligand-activated transcription factor, peroxisome proliferator-activated receptor-alpha (PPAR-α). In the present article, we describe the biochemical pathways responsible for the initiation and termination of OEA signaling, and outline the pharmacological properties of this compound in relation to its ability to activate PPAR-α. Finally, we discuss the possible role of OEA as a peripheral satiety hormone.
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peroxisome proliferator-activated receptor-alpha (PPAR-α)
lipid
feeding
satiety
energy balance
metabolism
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general
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Biochemistry
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