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Title:
Interleukin-17: a mediator of inflammatory responses | Cellular and Molecular Life Sciences
Description:
Interleukin-17 (IL-17) is a prototype member of a new cytokine family with six species identified to date. IL-17 is secreted mainly by activated CD4+ and CD8+ T lymphocytes, while its receptor is distributed ubiquitously. IL-17 has been classified as a proinflammatory cytokine because of its ability to induce the expression of many mediators of inflammation, most strikingly those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Increased levels of IL-17 have been associated with several conditions, including airway inflammation, rheumatoid arthritis, intraperitoneal abscesses and adhesions, inflammatory bowel disease, allograft rejection, psoriasis, cancer and multiple sclerosis. This review provides an overview of IL-17 activities, concentrating on those that lead to neutrophil recruitment.
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Keywords {🔍}
article, privacy, cookies, interleukin, witowski, content, information, publish, search, inflammation, data, journal, research, life, cmls, inflammatory, download, książek, jörres, cells, discover, author, optional, personal, including, parties, protection, policy, find, track, cellular, molecular, sciences, mediator, responses, review, cite, pdf, manuscript, explore, cytokine, conditions, september, related, subjects, chemokines, department, medical, received, rights,
Topics {✒️}
including airway inflammation privacy choices/manage cookies il-17-producing cells related subjects european economic area inflammatory bowel disease university medical school medical intensive care accepting optional cookies scope submit manuscript author correspondence conditions privacy policy journal finder publish data protection search search life sci article cite inflammatory responses interleukin-17 privacy policy article witowski personal data books a optional cookies manage preferences inflammation essential cookies cookies skip information journal publish usage analysis social media varying standards march 2004 volume 61 prototype member cytokine family species identified activated cd4+ distributed ubiquitously proinflammatory cytokine increased levels rheumatoid arthritis intraperitoneal abscesses allograft rejection multiple sclerosis neutrophil recruitment latest articles machine learning affiliations department universitätsklinikum charit�
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headline:Interleukin-17: a mediator of inflammatory responses
description:Interleukin-17 (IL-17) is a prototype member of a new cytokine family with six species identified to date. IL-17 is secreted mainly by activated CD4+ and CD8+ T lymphocytes, while its receptor is distributed ubiquitously. IL-17 has been classified as a proinflammatory cytokine because of its ability to induce the expression of many mediators of inflammation, most strikingly those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Increased levels of IL-17 have been associated with several conditions, including airway inflammation, rheumatoid arthritis, intraperitoneal abscesses and adhesions, inflammatory bowel disease, allograft rejection, psoriasis, cancer and multiple sclerosis. This review provides an overview of IL-17 activities, concentrating on those that lead to neutrophil recruitment.
datePublished:
dateModified:
pageStart:567
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keywords:
IL-17
T cells
inflammation
chemokines
granulopoiesis
Cell Biology
Biomedicine
general
Life Sciences
Biochemistry
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headline:Interleukin-17: a mediator of inflammatory responses
description:Interleukin-17 (IL-17) is a prototype member of a new cytokine family with six species identified to date. IL-17 is secreted mainly by activated CD4+ and CD8+ T lymphocytes, while its receptor is distributed ubiquitously. IL-17 has been classified as a proinflammatory cytokine because of its ability to induce the expression of many mediators of inflammation, most strikingly those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Increased levels of IL-17 have been associated with several conditions, including airway inflammation, rheumatoid arthritis, intraperitoneal abscesses and adhesions, inflammatory bowel disease, allograft rejection, psoriasis, cancer and multiple sclerosis. This review provides an overview of IL-17 activities, concentrating on those that lead to neutrophil recruitment.
datePublished:
dateModified:
pageStart:567
pageEnd:579
sameAs:https://doi.org/10.1007/s00018-003-3228-z
keywords:
IL-17
T cells
inflammation
chemokines
granulopoiesis
Cell Biology
Biomedicine
general
Life Sciences
Biochemistry
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