We are analyzing https://link.springer.com/article/10.1007/bf01252029.

Title:
Detection of 5-S-cysteinyldopamine in human brain | Journal of Neural Transmission
Description:
5-S-Cysteinyldopamine was synthesized and used as reference compound in HPLC analyses of extracts from various regions of human brain. The compound could be detected in brain regions rich in dopamine (caudate nucleus, putamen, globus pallidus and substantia nigra) but not in other regions (cerebellum, occipital cortex). The occurrence of 5-S-cysteinyldopamine in dopaminergic brain regions supports the hypothesis that dopamine in part undergoes autoxidation, leading to formation of highly reactive quinones. The newly discovered metabolite may prove useful in future studies of dopamine autoxidation and the possibly resultant cytotoxicity in aging and degenerative brain disorders.
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Topics {✒️}

month download article/chapter dopaminergic brain regions privacy choices/manage cookies degenerative brain disorders human nervous system eva linder-eliasson related subjects full article pdf brain regions rich human brain conditions privacy policy european economic area scope submit manuscript highly reactive quinones newly discovered metabolite future studies possibly resultant cytotoxicity red guinea pigs pigmented nerve cells neural transmission aims part undergoes autoxidation check access instant access accepting optional cookies journal finder publish 5-s-cysteinyl-dopa brain neurotransmitters related catechols linder-eliasson article journal carlsson rights article log neural transmission 63 privacy policy personal data september 1985 volume 63 oxidation properties books a article cite article rosengren optional cookies manage preferences 5-s-cysteinyldopamine dopamine autoxidation journal publish neural transm data protection subscription content similar content melanin content

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