We are analyzing https://link.springer.com/article/10.1007/bf00972490.

Title:
A phosphoinositide-linked peptide response in astrocytes: Evidence for regional heterogeneity | Neurochemical Research
Description:
A phosphoinositide-linked peptide response in cultured rat astrocytes was studied by measuring the accumulation of [3H]inositol phosphates in the presence of lithium. Cultures derived from cortex, cerebellum and spinal cord each showed a unique pattern or degree of stimulation to a panel of neuropeptides. Cortical and cerebellar astrocytes were similar, responding to bradykinin, oxytocin, vasopressin, eledoisin and neurokinin β, whereas spinal cord astrocytes were stimulated by substance P, bradykinin, eledoisin, and neurokinins α and β. These observations are evidence in favour of regional specialisations of astrocytes which may respond uniquely to peptidesreleased by particular populations of neurons.
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Keywords {🔍}

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Topics {✒️}

month download article/chapter phosphoinositide-linked peptide response cell-type-specific markers region-specific astrocyte subtypes somatostatin-sensitive adenylate cyclases somatostatin-sensitive adenylate cyclase vasoactive intestinal peptide privacy choices/manage cookies full article pdf central nervous system cellular neurobiology vol cell surface peptidases cultured rat astrocytes cyclic amp accumulation peptidenor organ-specific astrocyte transplantation method investigate astrocyte development receptor matching studies cultured brain cells peptide hormone receptors vasopressin stimulate release european economic area scope submit manuscript peptidergic neurotransmitter capable prostanoid forming capacity mis match problem magnocellular hypothalamic projections daguet de montety rat neural lobe lower brain stem conditions privacy policy α1-adrenergic receptors primary astrocyte cultures van calker accepting optional cookies [3h]inositol phosphates rat spinal cord spinal cord astrocytes putative vasopressin receptors check access instant access primary astroglial cultures journal finder publish des-arg-bradykinin related subjects article cholewinski adenylate cyclase corticotropin peptides article log regional heterogeneity

Questions {❓}

Is neuropharmacology merely the pharmacology of neurons—or are astrocytes important too?

Schema {🗺️}

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