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Title:
Breast cancer in Greenland-selected epidemiological, clinical, and histological features | Journal of Cancer Research and Clinical Oncology
Description:
Fifty-seven breast cancers were diagnosed among indigenous Greenlandic women from 1950 to 1974. An additional 22 cases registered between 1975 and 1979 represent a minimum number and were only used as basis for minimum incidence rates. Changes in age-adjusted rate, age-specific incidence pattern, and relative risk were consistent with an upward shift from a population of low risk between 1950 and 1969 to one of intermediate risk from 1970 onward, a finding that relates well to increased urbanization and westernization. The risk of breast cancer in Greenland may be associated with consumption of saturated fats but is seemingly not correlated to total fat intake which has always been on a par with high-risk Danish levels. An association with diet may in reality have been stronger than suggested but weakened by a counterbalancing effect of high fertility, especially in the youngest age groups. Evaluation of histological features and survival did not suggest differences which could favorably compare with findings in white population groups contrary to reported results from the population of Japan, also one of low risk and of mongoloid origin. Further studies should consider dietary intakes, endocrine variations, and breast fluid secretion with special attention to girls at the age of menarche.
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cancer, google, scholar, breast, greenland, article, risk, dietary, nat, inst, incidence, diet, scand, research, nielsen, hansen, women, danish, acta, macmahon, study, pathol, microbiol, privacy, cookies, content, journal, clinical, histological, epidemiology, population, age, studies, access, int, med, mammary, clemmesen, aetiology, patients, eds, vol, international, yuasa, data, information, publish, search, oncology, summary,
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month download article/chapter age-specific incidence pattern clinical oncology aims privacy choices/manage cookies full article pdf related subjects breast cancers malignant neoplasms ii high-risk danish levels mammary tumors induced elevated serum levels johns hopkins hospital european economic area scope submit manuscript polyunsaturated fatty acids youngest age groups breast fluid secretion breast secretory activity postpartum breast involution greenlandic medical statistics copenhagen county hospital female breast cancer familial breast cancer human breast cancer total fat intake malignant neoplasms iii malignant neoplasms iv seventh-day adventists age-adjusted rate lung cancer mortality breast-cancer rates conditions privacy policy age-standardized rates breast cancer incidence accepting optional cookies indigenous greenlandic women bilateral breast cancer sprague-dawley rats population-based series enhanced growth rate de palo breast-cancer patients breast cancer patients case control study check access instant access journal finder publish minimum incidence rates breast cancer risk greenland-selected epidemiological
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headline:Breast cancer in Greenland-selected epidemiological, clinical, and histological features
description:Fifty-seven breast cancers were diagnosed among indigenous Greenlandic women from 1950 to 1974. An additional 22 cases registered between 1975 and 1979 represent a minimum number and were only used as basis for minimum incidence rates. Changes in age-adjusted rate, age-specific incidence pattern, and relative risk were consistent with an upward shift from a population of low risk between 1950 and 1969 to one of intermediate risk from 1970 onward, a finding that relates well to increased urbanization and westernization. The risk of breast cancer in Greenland may be associated with consumption of saturated fats but is seemingly not correlated to total fat intake which has always been on a par with high-risk Danish levels. An association with diet may in reality have been stronger than suggested but weakened by a counterbalancing effect of high fertility, especially in the youngest age groups. Evaluation of histological features and survival did not suggest differences which could favorably compare with findings in white population groups contrary to reported results from the population of Japan, also one of low risk and of mongoloid origin. Further studies should consider dietary intakes, endocrine variations, and breast fluid secretion with special attention to girls at the age of menarche.
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Greenland
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Cancer Research
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headline:Breast cancer in Greenland-selected epidemiological, clinical, and histological features
description:Fifty-seven breast cancers were diagnosed among indigenous Greenlandic women from 1950 to 1974. An additional 22 cases registered between 1975 and 1979 represent a minimum number and were only used as basis for minimum incidence rates. Changes in age-adjusted rate, age-specific incidence pattern, and relative risk were consistent with an upward shift from a population of low risk between 1950 and 1969 to one of intermediate risk from 1970 onward, a finding that relates well to increased urbanization and westernization. The risk of breast cancer in Greenland may be associated with consumption of saturated fats but is seemingly not correlated to total fat intake which has always been on a par with high-risk Danish levels. An association with diet may in reality have been stronger than suggested but weakened by a counterbalancing effect of high fertility, especially in the youngest age groups. Evaluation of histological features and survival did not suggest differences which could favorably compare with findings in white population groups contrary to reported results from the population of Japan, also one of low risk and of mongoloid origin. Further studies should consider dietary intakes, endocrine variations, and breast fluid secretion with special attention to girls at the age of menarche.
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