We are analyzing https://link.springer.com/article/10.1007/bf00332977.

Title:
Four mutants of Micrococcus radiodurans defective in the ability to repair DNA damaged by mitomycin-C, two of which have wild-type resistance to ultraviolet radiation | Molecular Genetics and Genomics
Description:
Four genes concerned with the resistance of wild-type Micrococcus radiodurans to the lethal action of mitomycin-C (MTC), mtcA, mtcB, uvsA and uvsB, have been identified by isolating mutants sensitive to MTC. Two strains of M. radiodurans, 302 and 262 carrying mutations in mtcA and mtcB respectively, are between forty and sixty times as sensitive as the wild-type to MTC, only slightly more sensitive than the wild-type to ionizing (λ) radiation and have the same resistance as the wild-type to ultraviolet (u.v.) radiation. Strain 302 can be transformed at a high frequency to wild-type resistance to MTC with DNA from strain 262, and vice versa, indicating that mtcA and mtcB have different genetic locations. Two further strains of M. radiodurans, 303 and 263 having mutations in uvsA and uvsB respectively are only from four to eight times as sensitive as the wild-type to MTC, seven to thirteen times as sensitive to γ-radiation but between twenty to thirty-three times as sensitive to u.v. radiation. Strain 303 can be transformed with DNA from strain 263, or vice versa, to wild-type resistance to u.v. radiation, implying that uvsA and uvsB also have different genetic locations. M. radiodurans strain 301 which is mutant in both mtcA and uvsA, and strain 261 which is mutant in mtcB and uvsB are twenty to forty times as sensitive as the wild-type to both MTC and u.v. radiation and seven to ten times as sensitive to γ radiation. Neither mtcA and uvsA nor mtcB and uvsB are closely linked. None of the mutant strains is deficient in recombination, as measured by transformation. The repair of MTC-induced DNA damage in M. radiodurans must be different from that described for Escherichia coli.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Science
Telecommunications
Education

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 7,734,772 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We're unsure if the website is profiting.

Websites don't always need to be profitable; some serve as platforms for education or personal expression. Websites can serve multiple purposes. And this might be one of them. Link.springer.com might have a hidden revenue stream, but it's not something we can detect.

Keywords {🔍}

radiodurans, radiation, google, scholar, micrococcus, dna, article, wildtype, moseley, repair, resistance, sensitive, beb, strain, mutant, content, ultraviolet, mtc, times, coli, access, privacy, cookies, copland, mtca, mtcb, uvsa, uvsb, escherichia, mutation, information, publish, search, mutants, mitomycinc, recombination, isolation, microbiol, gen, data, log, journal, research, genetics, ability, damaged, genes, strains, genetic, damage,

Topics {✒️}

month download article/chapter deoxyribonucleic acid cross-links related subjects privacy choices/manage cookies mtc-induced dna damage temperature-sensitive dna mutant escherichia coli k-12 full article pdf wild-type micrococcus radiodurans ultraviolet-induced damage coli k-12 treated ultraviolet radiation published european economic area scope submit manuscript adaptive laboratory evolution recombination-deficient mutant repair dna damaged check access instant access conditions privacy policy accepting optional cookies monofunctional alkylating agents escherichia coli article molecular micrococcus radiodurans defective micrococcus radiodurans held main content log journal finder publish genes concerned wild-type resistance bacteria mutagenesis isolating mutants sensitive radiation-sensitive mutants ultraviolet radiation article log article moseley damage dna mutation signatures deoxyribonucleic acid mutation res auerbach rights damaged dna article cite privacy policy personal data dna content books a ultraviolet light genes

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Four mutants of Micrococcus radiodurans defective in the ability to repair DNA damaged by mitomycin-C, two of which have wild-type resistance to ultraviolet radiation
         description:Four genes concerned with the resistance of wild-type Micrococcus radiodurans to the lethal action of mitomycin-C (MTC), mtcA, mtcB, uvsA and uvsB, have been identified by isolating mutants sensitive to MTC. Two strains of M. radiodurans, 302 and 262 carrying mutations in mtcA and mtcB respectively, are between forty and sixty times as sensitive as the wild-type to MTC, only slightly more sensitive than the wild-type to ionizing (λ) radiation and have the same resistance as the wild-type to ultraviolet (u.v.) radiation. Strain 302 can be transformed at a high frequency to wild-type resistance to MTC with DNA from strain 262, and vice versa, indicating that mtcA and mtcB have different genetic locations. Two further strains of M. radiodurans, 303 and 263 having mutations in uvsA and uvsB respectively are only from four to eight times as sensitive as the wild-type to MTC, seven to thirteen times as sensitive to γ-radiation but between twenty to thirty-three times as sensitive to u.v. radiation. Strain 303 can be transformed with DNA from strain 263, or vice versa, to wild-type resistance to u.v. radiation, implying that uvsA and uvsB also have different genetic locations. M. radiodurans strain 301 which is mutant in both mtcA and uvsA, and strain 261 which is mutant in mtcB and uvsB are twenty to forty times as sensitive as the wild-type to both MTC and u.v. radiation and seven to ten times as sensitive to γ radiation. Neither mtcA and uvsA nor mtcB and uvsB are closely linked. None of the mutant strains is deficient in recombination, as measured by transformation. The repair of MTC-induced DNA damage in M. radiodurans must be different from that described for Escherichia coli.
         datePublished:
         dateModified:
         pageStart:331
         pageEnd:337
         sameAs:https://doi.org/10.1007/BF00332977
         keywords:
            Radiation
            Escherichia Coli
            Recombination
            Mutant Strain
            Ultraviolet Radiation
            Plant Genetics and Genomics
            Human Genetics
            Microbial Genetics and Genomics
            Animal Genetics and Genomics
            Biochemistry
            general
         image:
         isPartOf:
            name:Molecular and General Genetics MGG
            issn:
               1432-1874
               0026-8925
            volumeNumber:160
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer-Verlag
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:B. E. B. Moseley
               affiliation:
                     name:University of Edinburgh, School of Agriculture
                     address:
                        name:Department of Microbiology, University of Edinburgh, School of Agriculture, Edinburgh, Scotland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:H. J. R. Copland
               affiliation:
                     name:University of Edinburgh, School of Agriculture
                     address:
                        name:Department of Microbiology, University of Edinburgh, School of Agriculture, Edinburgh, Scotland
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Four mutants of Micrococcus radiodurans defective in the ability to repair DNA damaged by mitomycin-C, two of which have wild-type resistance to ultraviolet radiation
      description:Four genes concerned with the resistance of wild-type Micrococcus radiodurans to the lethal action of mitomycin-C (MTC), mtcA, mtcB, uvsA and uvsB, have been identified by isolating mutants sensitive to MTC. Two strains of M. radiodurans, 302 and 262 carrying mutations in mtcA and mtcB respectively, are between forty and sixty times as sensitive as the wild-type to MTC, only slightly more sensitive than the wild-type to ionizing (λ) radiation and have the same resistance as the wild-type to ultraviolet (u.v.) radiation. Strain 302 can be transformed at a high frequency to wild-type resistance to MTC with DNA from strain 262, and vice versa, indicating that mtcA and mtcB have different genetic locations. Two further strains of M. radiodurans, 303 and 263 having mutations in uvsA and uvsB respectively are only from four to eight times as sensitive as the wild-type to MTC, seven to thirteen times as sensitive to γ-radiation but between twenty to thirty-three times as sensitive to u.v. radiation. Strain 303 can be transformed with DNA from strain 263, or vice versa, to wild-type resistance to u.v. radiation, implying that uvsA and uvsB also have different genetic locations. M. radiodurans strain 301 which is mutant in both mtcA and uvsA, and strain 261 which is mutant in mtcB and uvsB are twenty to forty times as sensitive as the wild-type to both MTC and u.v. radiation and seven to ten times as sensitive to γ radiation. Neither mtcA and uvsA nor mtcB and uvsB are closely linked. None of the mutant strains is deficient in recombination, as measured by transformation. The repair of MTC-induced DNA damage in M. radiodurans must be different from that described for Escherichia coli.
      datePublished:
      dateModified:
      pageStart:331
      pageEnd:337
      sameAs:https://doi.org/10.1007/BF00332977
      keywords:
         Radiation
         Escherichia Coli
         Recombination
         Mutant Strain
         Ultraviolet Radiation
         Plant Genetics and Genomics
         Human Genetics
         Microbial Genetics and Genomics
         Animal Genetics and Genomics
         Biochemistry
         general
      image:
      isPartOf:
         name:Molecular and General Genetics MGG
         issn:
            1432-1874
            0026-8925
         volumeNumber:160
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer-Verlag
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:B. E. B. Moseley
            affiliation:
                  name:University of Edinburgh, School of Agriculture
                  address:
                     name:Department of Microbiology, University of Edinburgh, School of Agriculture, Edinburgh, Scotland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:H. J. R. Copland
            affiliation:
                  name:University of Edinburgh, School of Agriculture
                  address:
                     name:Department of Microbiology, University of Edinburgh, School of Agriculture, Edinburgh, Scotland
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Molecular and General Genetics MGG
      issn:
         1432-1874
         0026-8925
      volumeNumber:160
Organization:
      name:Springer-Verlag
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Edinburgh, School of Agriculture
      address:
         name:Department of Microbiology, University of Edinburgh, School of Agriculture, Edinburgh, Scotland
         type:PostalAddress
      name:University of Edinburgh, School of Agriculture
      address:
         name:Department of Microbiology, University of Edinburgh, School of Agriculture, Edinburgh, Scotland
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:B. E. B. Moseley
      affiliation:
            name:University of Edinburgh, School of Agriculture
            address:
               name:Department of Microbiology, University of Edinburgh, School of Agriculture, Edinburgh, Scotland
               type:PostalAddress
            type:Organization
      name:H. J. R. Copland
      affiliation:
            name:University of Edinburgh, School of Agriculture
            address:
               name:Department of Microbiology, University of Edinburgh, School of Agriculture, Edinburgh, Scotland
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Department of Microbiology, University of Edinburgh, School of Agriculture, Edinburgh, Scotland
      name:Department of Microbiology, University of Edinburgh, School of Agriculture, Edinburgh, Scotland
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(42)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.75s.

LINK . SPRINGER . COM {}