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Coronary Artery Disease: From Mechanism to Clinical Practice | SpringerLink
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In most developed countries, coronary artery disease (CAD), mostly caused by atherosclerosis of coronary arteries, is one of the primary causes of death. From 1990s to 2000s, mortality caused by acute MI declined up to 50%. The incidence of CAD is related with age,...
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google, scholar, pubmed, article, cas, disease, cardiovascular, risk, myocardial, heart, infarction, coronary, med, study, circulation, factors, atherosclerosis, acute, patients, diabetes, ventricular, central, artery, mortality, cardiol, cholesterol, jama, vascular, left, engl, association, chapter, lancet, men, intern, blood, adults, stroke, clinical, diseases, women, eur, ann, china, res, national, incidence, history, angina, treatment,
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org/content/dam/worldbank/document/ncd_report_en jian tian & yi-da tang month download article/chapter carotid intimal-medial thickness glycoprotein iib/iiia inhibitors acc/aha/ase committee 2013 aha/acc/tos guideline angiotensin-converting enzyme inhibitors st-elevation myocardial infarction post-infarction ventricular remodeling ldl receptor-deficient mice c-reactive protein concentration health-care reform plan post-myocardial infarction syndrome italian case-control study org/qualityandscience/clinical/statements asia pacific region low risk-factor profile endothelium-derived nitric oxide left ventricular thrombus left ventricular dysfunction acute myocardial infarction—results case fatality rates yi-da tang typical angina pectoris left ventricular aneurysm left ventricular pseudoaneurysm privacy choices/manage cookies severe angina pectoris van de werf device instant download individual participant meta-analysis magnetic resonance imaging american heart association c-reactive protein editor information editors coronary artery disease acute mi declined randomized controlled trials ventricular septal rupture interdisciplinary working group case-control study canadian cardiovascular society acute myocardial infarction myocardial infarction complicated sensitive mi biomarkers primary percutaneous intervention antioxidant gene therapy acc/aha guidelines reykjavik cohort study
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- Ridker PM (1999) Evaluating novel cardiovascular risk factors: can we better predict heart attacks?
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ScholarlyArticle:
headline:Coronary Artery Disease: From Mechanism to Clinical Practice
pageEnd:36
pageStart:1
image:https://media.springernature.com/w153/springer-static/cover/book/978-981-15-2517-9.jpg
genre:
Biomedical and Life Sciences
Biomedical and Life Sciences (R0)
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isbn:
978-981-15-2517-9
978-981-15-2516-2
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author:
name:Chunli Shao
affiliation:
name:Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College
address:
name:Department of Cardiology, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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name:Jingjia Wang
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name:Department of Cardiology, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
type:PostalAddress
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name:Jian Tian
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keywords:Epidemiology, Risk factors, Clinical presentation, Complication, Pathophysiology
description:In most developed countries, coronary artery disease (CAD), mostly caused by atherosclerosis of coronary arteries, is one of the primary causes of death. From 1990s to 2000s, mortality caused by acute MI declined up to 50%. The incidence of CAD is related with age, gender, economic, etc. Atherosclerosis contains some highly correlative processes such as lipid disturbances, thrombosis, inflammation, vascular smooth cell activation, remodeling, platelet activation, endothelial dysfunction, oxidative stress, altered matrix metabolism, and genetic factors. Risk factors of CAD exist among many individuals of the general population, which includes hypertension, lipids and lipoproteins metabolism disturbances, diabetes mellitus, chronic kidney disease, age, genders, lifestyle, cigarette smoking, diet, obesity, and family history. Angina pectoris is caused by myocardial ischemia in the main expression of pain in the chest or adjoining area, which is usually a result of exertion and related to myocardial function disorder. Typical angina pectoris would last for minutes with gradual exacerbation. Rest, sit, or stop walking are the usual preference for patients with angina, and reaching the maximum intensity in seconds is uncommon. Rest or nitroglycerin usage can relieve typical angina pectoris within minutes. So far, a widely accepted angina pectoris severity grading system included CCS (Canadian Cardiovascular Society) classification, Califf score, and Goldman scale. Patients with ST-segment elevated myocardial infarction (STEMI) may have different symptoms and signs of both severe angina pectoris and various complications. The combination of rising usage of sensitive MI biomarkers and precise imaging techniques, including electrocardiograph (ECG), computed tomography, and cardiac magnetic resonance imaging, made the new MI criteria necessary. Complications of acute myocardial infarction include left ventricular dysfunction, cardiogenic shock, structural complications, arrhythmia, recurrent chest discomfort, recurrent ischemia and infarction, pericardial effusion, pericarditis, post-myocardial infarction syndrome, venous thrombosis pulmonary embolism, left ventricular aneurysm, left ventricular thrombus, and arterial embolism.
datePublished:2020
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