We are analyzing https://link.springer.com/chapter/10.1007/978-94-017-8881-6_2.

Title:
Distribution of MACPF/CDC Proteins | SpringerLink
Description:
Membrane Attack Complex/Perforin (MACPF) and Cholesterol-Dependent Cytolysins (CDC) form the MACPF/CDC superfamily of important effector proteins widespread in nature. MACPFs and CDCs were discovered separately with no sequence similarity at that stage being apparent...
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Schema {🗺️}

ScholarlyArticle:
      headline:Distribution of MACPF/CDC Proteins
      pageEnd:30
      pageStart:7
      image:https://media.springernature.com/w153/springer-static/cover/book/978-94-017-8881-6.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:MACPF/CDC Proteins - Agents of Defence, Attack and Invasion
         isbn:
            978-94-017-8881-6
            978-94-017-8880-9
         type:Book
      publisher:
         name:Springer Netherlands
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Gregor Anderluh
            affiliation:
                  name:National Institute of Chemistry
                  address:
                     name:Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
                     type:PostalAddress
                  type:Organization
                  name:University of Ljubljana
                  address:
                     name:Department of Biology, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Matic Kisovec
            affiliation:
                  name:National Institute of Chemistry
                  address:
                     name:Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Nada Kraševec
            affiliation:
                  name:National Institute of Chemistry
                  address:
                     name:Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Robert J. C. Gilbert
            affiliation:
                  name:University of Oxford
                  address:
                     name:Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      keywords:Cholesterol-dependent cytolysins, MACPF/CDC protein superfamily, Membrane attack complex, Perforin, Protein evolution
      description:Membrane Attack Complex/Perforin (MACPF) and Cholesterol-Dependent Cytolysins (CDC) form the MACPF/CDC superfamily of important effector proteins widespread in nature. MACPFs and CDCs were discovered separately with no sequence similarity at that stage being apparent between the two protein families such that they were not, until recently, considered evolutionary related. The breakthrough showing they are came with recent structural work that also shed light on the molecular mechanism of action of various MACPF proteins. Similarity in structural properties and conserved functional features indicate that both protein families have the same evolutionary origin. We will describe the distribution of MACPF/CDC proteins in nature and discuss briefly their similarity and functional role in different biological processes.
      datePublished:2014
      isAccessibleForFree:
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      context:https://schema.org
Book:
      name:MACPF/CDC Proteins - Agents of Defence, Attack and Invasion
      isbn:
         978-94-017-8881-6
         978-94-017-8880-9
Organization:
      name:Springer Netherlands
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:National Institute of Chemistry
      address:
         name:Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
         type:PostalAddress
      name:University of Ljubljana
      address:
         name:Department of Biology, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia
         type:PostalAddress
      name:National Institute of Chemistry
      address:
         name:Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
         type:PostalAddress
      name:National Institute of Chemistry
      address:
         name:Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
         type:PostalAddress
      name:University of Oxford
      address:
         name:Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Gregor Anderluh
      affiliation:
            name:National Institute of Chemistry
            address:
               name:Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
               type:PostalAddress
            type:Organization
            name:University of Ljubljana
            address:
               name:Department of Biology, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Matic Kisovec
      affiliation:
            name:National Institute of Chemistry
            address:
               name:Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
               type:PostalAddress
            type:Organization
      name:Nada Kraševec
      affiliation:
            name:National Institute of Chemistry
            address:
               name:Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
               type:PostalAddress
            type:Organization
      name:Robert J. C. Gilbert
      affiliation:
            name:University of Oxford
            address:
               name:Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
      name:Department of Biology, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia
      name:Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
      name:Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
      name:Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
WebPageElement:
      isAccessibleForFree:
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