We are analyzing https://link.springer.com/chapter/10.1007/978-94-007-5561-1_5.

Title:
Intracellular Calcium Homeostasis and Signaling | SpringerLink
Description:
Ca2+ is a universal carrier of biological information: it controls cell life from its origin at fertilization to its end in the process of programmed cell death. Ca2+ is a conventional diffusible second messenger released inside cells by the interaction of first...
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Education
Telecommunications
Science

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We're unsure if the website is profiting.

Websites don't always need to be profitable; some serve as platforms for education or personal expression. Websites can serve multiple purposes. And this might be one of them. Link.springer.com has a revenue plan, but it's either invisible or we haven't found it.

Keywords {🔍}

google, scholar, cas, article, pubmed, biol, cell, chem, carafoli, calcium, nature, sci, physiol, biochem, science, rev, rizzuto, chapter, brini, acad, mol, membrane, receptor, usa, biophys, pozzan, information, mitochondrial, proc, natl, nat, university, springer, embo, life, cells, protein, cold, spring, harbor, perspect, guerini, res, santella, padova, privacy, cookies, content, publish, research,

Topics {✒️}

n-methyl-d-aspartate omm month download article/chapter article google scholar cas google scholar high ca2+ affinity plasma membrane receptors privacy choices/manage cookies intracellular calcium homeostasis device instant download plasma membrane receptor ca2+ uptake system pure ca2+ buffers modeling calcium signaling international hapmap consortium editor information editors movements inside cells conditions privacy policy european economic area integrated project eurohear google scholar author information authors van den bosch ca2+ signal regulates accepting optional cookies mediates cell distress low transport capacity programmed cell death main content log cell marisa brini controls cell life messenger phosphoprotein res journal finder publish social media tito calì affiliations department permissions reprints china life sci chapter usd 29 check access calcium homeostasis science signalling ethics access signaling chapter plasma membrane oxford university press chapter metallomics protein kinase chapter cite privacy policy trends cell biol

Schema {🗺️}

ScholarlyArticle:
      headline:Intracellular Calcium Homeostasis and Signaling
      pageEnd:168
      pageStart:119
      image:https://media.springernature.com/w153/springer-static/cover/book/978-94-007-5561-1.jpg
      genre:
         Chemistry and Materials Science
         Chemistry and Material Science (R0)
      isPartOf:
         name:Metallomics and the Cell
         isbn:
            978-94-007-5561-1
            978-94-007-5560-4
         type:Book
      publisher:
         name:Springer Netherlands
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Marisa Brini
            affiliation:
                  name:University of Padova
                  address:
                     name:Department of Comparative Biomedicine and Food Sciences, University of Padova, Padova, Italy
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Tito Calì
            affiliation:
                  name:University of Padova
                  address:
                     name:Department of Comparative Biomedicine and Food Sciences, University of Padova, Padova, Italy
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Denis Ottolini
            affiliation:
                  name:University of Padova
                  address:
                     name:Department of Biomedical Sciences, University of Padova, Padova, Italy
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ernesto Carafoli
            affiliation:
                  name:Venetian Institute of Molecular Medicine (VIMM)
                  address:
                     name:Venetian Institute of Molecular Medicine (VIMM), Padova, Italy
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      keywords:apoptosis, calcium, calcium buffering proteins, calcium sensor proteins, calmodulin, fertilization, gene expression, ion pumps, mitochondria, protein dephosphorylation, protein phosphorylation, Please cite as: Met. Ions Life Sci. 12 (2013) 119–168
      description:Ca2+ is a universal carrier of biological information: it controls cell life from its origin at fertilization to its end in the process of programmed cell death. Ca2+ is a conventional diffusible second messenger released inside cells by the interaction of first messengers with plasma membrane receptors. However, it can also penetrate directly into cells to deliver information without the intermediation of first or second messengers. Even more distinctively, Ca2+ can act as a first messenger, by interacting with a plasma membrane receptor to set in motion intracellular signaling pathways that involve Ca2+ itself. Perhaps the most distinctive property of the Ca2+ signal is its ambivalence: while essential to the correct functioning of cells, Ca2+ becomes an agent that mediates cell distress, or even (toxic) cell death, if its concentration and movements inside cells are not carefully tuned. Ca2+ is controlled by reversible complexation to specific proteins, which could be pure Ca2+ buffers, or which, in addition to buffering Ca2+, also decode its signal to pass it on to targets. The most important actors in the buffering of cell Ca2+ are proteins that transport it across the plasma membrane and the membrane of the organelles: some have high Ca2+ affinity and low transport capacity (e.g., Ca2+ pumps), others have opposite properties (e.g., the Ca2+ uptake system of mitochondria). Between the initial event of fertilization, and the terminal event of programmed cell death, the Ca2+ signal regulates the most important activities of the cell, from the expression of genes, to heart and muscle contraction and other motility processes, to diverse metabolic pathways involved in the generation of cell fuels.
      datePublished:2013
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
      context:https://schema.org
Book:
      name:Metallomics and the Cell
      isbn:
         978-94-007-5561-1
         978-94-007-5560-4
Organization:
      name:Springer Netherlands
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Padova
      address:
         name:Department of Comparative Biomedicine and Food Sciences, University of Padova, Padova, Italy
         type:PostalAddress
      name:University of Padova
      address:
         name:Department of Comparative Biomedicine and Food Sciences, University of Padova, Padova, Italy
         type:PostalAddress
      name:University of Padova
      address:
         name:Department of Biomedical Sciences, University of Padova, Padova, Italy
         type:PostalAddress
      name:Venetian Institute of Molecular Medicine (VIMM)
      address:
         name:Venetian Institute of Molecular Medicine (VIMM), Padova, Italy
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Marisa Brini
      affiliation:
            name:University of Padova
            address:
               name:Department of Comparative Biomedicine and Food Sciences, University of Padova, Padova, Italy
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Tito Calì
      affiliation:
            name:University of Padova
            address:
               name:Department of Comparative Biomedicine and Food Sciences, University of Padova, Padova, Italy
               type:PostalAddress
            type:Organization
      name:Denis Ottolini
      affiliation:
            name:University of Padova
            address:
               name:Department of Biomedical Sciences, University of Padova, Padova, Italy
               type:PostalAddress
            type:Organization
      name:Ernesto Carafoli
      affiliation:
            name:Venetian Institute of Molecular Medicine (VIMM)
            address:
               name:Venetian Institute of Molecular Medicine (VIMM), Padova, Italy
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Comparative Biomedicine and Food Sciences, University of Padova, Padova, Italy
      name:Department of Comparative Biomedicine and Food Sciences, University of Padova, Padova, Italy
      name:Department of Biomedical Sciences, University of Padova, Padova, Italy
      name:Venetian Institute of Molecular Medicine (VIMM), Padova, Italy
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(540)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js

5.15s.

LINK . SPRINGER . COM {}