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Title:
Biobanking of Cerebrospinal Fluid for Biomarker Analysis in Neurological Diseases | SpringerLink
Description:
Cerebrospinal fluid (CSF) reflects pathophysiological aspects of neurological diseases, where neuroprotective strategies and biomarkers are urgently needed. Therefore, biobanking is very relevant for biomarker discovery and evaluation for these neurological diseases....
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Questions {❓}

Carrette O, Burkhard PR, Hughes S, Hochstrasser DF, Sanchez J-C (2005) Truncated cystatin C in cerebrospiral fluid: technical [corrected] artefact or biological process?
Downer EJ, Campbell VA (2010) Phytocannabinoids, CNS cells and development: a dead issue?
Lomholt AF, Frederiksen CB, Christensen IJ, Brünner N, Nielsen HJ (2007) Plasma tissue inhibitor of metalloproteinases-1 as a biological marker?
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Schema {🗺️}

ScholarlyArticle:
      headline:Biobanking of Cerebrospinal Fluid for Biomarker Analysis in Neurological Diseases
      pageEnd:93
      pageStart:79
      image:https://media.springernature.com/w153/springer-static/cover/book/978-3-319-20579-3.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:Biobanking in the 21st Century
         isbn:
            978-3-319-20579-3
            978-3-319-20578-6
         type:Book
      publisher:
         name:Springer International Publishing
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Eline A. J. Willemse
            affiliation:
                  name:VU University Medical Center Amsterdam
                  address:
                     name:Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, VU University Medical Center Amsterdam, Amsterdam, The Netherlands
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Charlotte E. Teunissen
            affiliation:
                  name:VU University Medical Center Amsterdam
                  address:
                     name:Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, VU University Medical Center Amsterdam, Amsterdam, The Netherlands
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      keywords:Biobank, Cerebrospinal fluid, Neurology, Biomarkers, Quality control
      description:Cerebrospinal fluid (CSF) reflects pathophysiological aspects of neurological diseases, where neuroprotective strategies and biomarkers are urgently needed. Therefore, biobanking is very relevant for biomarker discovery and evaluation for these neurological diseases. An important aspect of CSF biobanking is quality control, needed for e.g. consistent patient follow-up and the exchange of patient samples between research centers. Systematic studies to address effects of pre-analytical and storage variation on a broad range of CSF proteins are needed and initiated. Important features of CSF biobanking are intensive collaboration in international networks and the tight application of standardized protocols. The current adoption of standardized protocols for CSF and blood collection and for biobanking of these samples, as presented in this chapter, enables biomarker studies in large cohorts of patients and controls. In conclusion, biomarker research in neurodegenerative diseases has entered a new era due to the collaborative and multicenter efforts of many groups. The streamlining of biobanking procedures, including sample collection, quality control, and the selection of optimal control groups for investigating biomarkers is an important improvement to perform high quality biomarker studies.
      datePublished:2015
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Book:
      name:Biobanking in the 21st Century
      isbn:
         978-3-319-20579-3
         978-3-319-20578-6
Organization:
      name:Springer International Publishing
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:VU University Medical Center Amsterdam
      address:
         name:Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, VU University Medical Center Amsterdam, Amsterdam, The Netherlands
         type:PostalAddress
      name:VU University Medical Center Amsterdam
      address:
         name:Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, VU University Medical Center Amsterdam, Amsterdam, The Netherlands
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Eline A. J. Willemse
      affiliation:
            name:VU University Medical Center Amsterdam
            address:
               name:Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, VU University Medical Center Amsterdam, Amsterdam, The Netherlands
               type:PostalAddress
            type:Organization
      name:Charlotte E. Teunissen
      affiliation:
            name:VU University Medical Center Amsterdam
            address:
               name:Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, VU University Medical Center Amsterdam, Amsterdam, The Netherlands
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, VU University Medical Center Amsterdam, Amsterdam, The Netherlands
      name:Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, VU University Medical Center Amsterdam, Amsterdam, The Netherlands
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