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Title:
The Identification of the Component in the Inner Membrane of Brown Adipose Tissue Mitochondria Responsible for Regulating Energy Dissipation | SpringerLink
Description:
The proton conductance of the inner membrane of hamster brown adipose tissue mitochondria can be regulated in vitro by exogenous purine nucleotides, which “bind to a component on the outer face of the inner membrane. This unique mechanism has been proposed to...
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Keywords {🔍}
google, scholar, article, brown, tissue, privacy, cookies, content, information, publish, thermogenesis, paper, adipose, nicholls, search, component, membrane, bernson, preview, ear, biochem, data, log, journal, research, effectors, conference, mitochondria, heaton, access, download, chapter, mcholls, springer, basel, site, function, optional, personal, parties, policy, find, track, identification, responsible, regulating, energy, dissipation, cite, david,
Topics {✒️}
regulating energy dissipation privacy choices/manage cookies conference paper effectors download preview pdf european economic area exogenous purine nucleotides photo-affinity analogue journal finder publish conditions privacy policy accepting optional cookies book series ninewells medical school paper cite main content log nucleotide binding component brown adipocytes permissions reprints journal publish paper nicholls privacy policy basel personal data check access ethics access chapter log books a thermogenesis david shivering thermogenesis optional cookies function manage preferences medical school tissue data protection essential cookies cookies skip subscription content similar content nicholls & gillian usage analysis social media varying standards information bernson & gillian heaton part experientia supplementum proton conductance outer face unique mechanism preview unable
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ScholarlyArticle:
headline:The Identification of the Component in the Inner Membrane of Brown Adipose Tissue Mitochondria Responsible for Regulating Energy Dissipation
pageEnd:93
pageStart:89
image:https://media.springernature.com/w153/springer-static/cover/book/978-3-0348-5559-4.jpg
genre:
Biomedical and Life Sciences
Biomedical and Life Sciences (R0)
isPartOf:
name:Effectors of Thermogenesis
isbn:
978-3-0348-5559-4
978-3-0348-5561-7
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publisher:
name:Birkhäuser Basel
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
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type:Organization
author:
name:David G. Nicholls
affiliation:
name:Dundee University
address:
name:Departments of Psychiatry and Biochemical Medicine, Ninewells Medical School, Dundee University, Dundee, Scotland, UK
type:PostalAddress
type:Organization
type:Person
name:Vibeke S. M. Bernson
affiliation:
name:Stockholm Universitet
address:
name:Wennergrens Institut, Stockholm Universitet, Stockholm, Sweden
type:PostalAddress
type:Organization
type:Person
name:Gillian M. Heaton
affiliation:
name:Dundee University
address:
name:Departments of Psychiatry and Biochemical Medicine, Ninewells Medical School, Dundee University, Dundee, Scotland, UK
type:PostalAddress
type:Organization
type:Person
keywords:Brown Adipose Tissue, Proton Conductance, Outer Face, Purine Nucleotide, Adenine Nucleotide Translocase
description:The proton conductance of the inner membrane of hamster brown adipose tissue mitochondria can be regulated in vitro by exogenous purine nucleotides, which “bind to a component on the outer face of the inner membrane. This unique mechanism has been proposed to represent the molecular site of non-shivering thermogenesis in this tissue. Using a photo-affinity analogue of ATP, we have identified the nucleotide binding component as a protein of 32,000 daltons.
datePublished:1978
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