We are analyzing https://link.springer.com/chapter/10.1007/978-3-030-35805-1_8.

Title:
Epigenetics of Circulating Tumor Cells in Breast Cancer | SpringerLink
Description:
Liquid biopsy based on the analysis of circulating tumor cells (CTCs) has emerged as an important field of research. Molecular characterization of CTCs can provide insights into cancer biology and biomarkers for the clinic, representing a non-invasive powerful tool...
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Schema {🗺️}

ScholarlyArticle:
      headline:Epigenetics of Circulating Tumor Cells in Breast Cancer
      pageEnd:134
      pageStart:117
      image:https://media.springernature.com/w153/springer-static/cover/book/978-3-030-35805-1.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:Circulating Tumor Cells in Breast Cancer Metastatic Disease
         isbn:
            978-3-030-35805-1
            978-3-030-35804-4
         type:Book
      publisher:
         name:Springer International Publishing
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Aida Bao-Caamano
            affiliation:
                  name:University Clinical Hospital of Santiago (CHUS/SERGAS)
                  address:
                     name:Cancer Epigenomics, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Aitor Rodriguez-Casanova
            affiliation:
                  name:University Clinical Hospital of Santiago (CHUS/SERGAS)
                  address:
                     name:Cancer Epigenomics, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain
                     type:PostalAddress
                  type:Organization
                  name:Health Research Institute of Santiago de Compostela
                  address:
                     name:Roche-Chus Joint Unit, Translational Medical Oncology Group (Oncomet), Health Research Institute of Santiago de Compostela, Santiago de Compostela, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Angel Diaz-Lagares
            affiliation:
                  name:University Clinical Hospital of Santiago (CHUS/SERGAS)
                  address:
                     name:Cancer Epigenomics, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain
                     type:PostalAddress
                  type:Organization
                  name:Centro de Investigación Biomédica en Red Cáncer (CIBERONC)
                  address:
                     name:Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, Spain
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      keywords:Epigenetics, DNA methylation, Noncoding RNAs, Circulating tumor cells, CTC, Liquid biopsy, Breast cancer
      description:Liquid biopsy based on the analysis of circulating tumor cells (CTCs) has emerged as an important field of research. Molecular characterization of CTCs can provide insights into cancer biology and biomarkers for the clinic, representing a non-invasive powerful tool for monitoring breast cancer metastasis and predict the therapeutic response. Epigenetic mechanisms play a key role in the control of gene expression and their alteration contributes to cancer development and progression. These epigenetic modifications in CTCs have been described mainly related to modifications of the DNA methylation pattern and changes in the expression profile of noncoding RNAs. Here we summarize the recent findings on the epigenetic characterization of CTCs in breast cancer and their clinical value as tumor biomarkers, and discuss challenges and opportunities in this field.
      datePublished:2020
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Book:
      name:Circulating Tumor Cells in Breast Cancer Metastatic Disease
      isbn:
         978-3-030-35805-1
         978-3-030-35804-4
Organization:
      name:Springer International Publishing
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University Clinical Hospital of Santiago (CHUS/SERGAS)
      address:
         name:Cancer Epigenomics, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain
         type:PostalAddress
      name:University Clinical Hospital of Santiago (CHUS/SERGAS)
      address:
         name:Cancer Epigenomics, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain
         type:PostalAddress
      name:Health Research Institute of Santiago de Compostela
      address:
         name:Roche-Chus Joint Unit, Translational Medical Oncology Group (Oncomet), Health Research Institute of Santiago de Compostela, Santiago de Compostela, Spain
         type:PostalAddress
      name:University Clinical Hospital of Santiago (CHUS/SERGAS)
      address:
         name:Cancer Epigenomics, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain
         type:PostalAddress
      name:Centro de Investigación Biomédica en Red Cáncer (CIBERONC)
      address:
         name:Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, Spain
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Aida Bao-Caamano
      affiliation:
            name:University Clinical Hospital of Santiago (CHUS/SERGAS)
            address:
               name:Cancer Epigenomics, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain
               type:PostalAddress
            type:Organization
      name:Aitor Rodriguez-Casanova
      affiliation:
            name:University Clinical Hospital of Santiago (CHUS/SERGAS)
            address:
               name:Cancer Epigenomics, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain
               type:PostalAddress
            type:Organization
            name:Health Research Institute of Santiago de Compostela
            address:
               name:Roche-Chus Joint Unit, Translational Medical Oncology Group (Oncomet), Health Research Institute of Santiago de Compostela, Santiago de Compostela, Spain
               type:PostalAddress
            type:Organization
      name:Angel Diaz-Lagares
      affiliation:
            name:University Clinical Hospital of Santiago (CHUS/SERGAS)
            address:
               name:Cancer Epigenomics, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain
               type:PostalAddress
            type:Organization
            name:Centro de Investigación Biomédica en Red Cáncer (CIBERONC)
            address:
               name:Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, Spain
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Cancer Epigenomics, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain
      name:Cancer Epigenomics, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain
      name:Roche-Chus Joint Unit, Translational Medical Oncology Group (Oncomet), Health Research Institute of Santiago de Compostela, Santiago de Compostela, Spain
      name:Cancer Epigenomics, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain
      name:Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, Spain
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