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Title:
RNA Consensus Structure Prediction With RNAalifold | SpringerLink
Description:
The secondary structure of most functional RNA molecules is strongly conserved in evolution. Prediction of these conserved structures is therefore of particular interest when studying noncoding RNAs. Moreover, structure predictions on the basis of several sequences...
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Keywords {π}
rna, google, scholar, article, structure, pubmed, prediction, cas, secondary, sequences, bioinformatics, hofacker, information, comparative, consensus, biol, privacy, cookies, content, publish, protocol, structures, sequence, alignment, search, genomics, rnaalifold, rnas, folding, chapter, stadler, mol, bmc, data, log, journal, research, conserved, aligned, access, multiple, acids, res, gardner, press, optional, personal, including, parties, policy,
Topics {βοΈ}
stochastic context-free grammars nearest-neighbor energy parameters consensus structure prediction rna secondary structure rna secondary structures secondary structure prediction privacy choices/manage cookies predicting rna structure secondary structure common optimal computer folding rna structure evolution secondary structures conserved larger rna sequences free-energy minimization humana press sequence structure comparisons functional rna molecules aligned rna sequences comparative genomics journal finder publish european economic area genome-wide surveys ieee/acm trans accelerated probabilistic inference michigan medical school energy directed folding proto-sequence problems expanded sequence dependence conditions privacy policy consensus structure aligned sequences taking nucleic acids res studying noncoding rnas rnaalifold program predicts accepting optional cookies protocol hofacker secondary structure main content log protocol cite consensus folding rna sequences chapter log rna folding multiple alignment journal publish conserved structures structure predictions bmc bioinformatic 5 privacy policy personal data
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ScholarlyArticle:
headline:RNA Consensus Structure Prediction With RNAalifold
pageEnd:543
pageStart:527
image:https://media.springernature.com/w153/springer-static/cover/book/978-1-59745-514-5.jpg
genre:
Springer Protocols
isPartOf:
name:Comparative Genomics
isbn:
978-1-59745-514-5
978-1-58829-693-1
type:Book
publisher:
name:Humana Press
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Ivo L. Hofacker
affiliation:
name:University of Vienna
address:
name:Department of Theoretical Chemistry, University of Vienna, Vienna
type:PostalAddress
type:Organization
type:Person
keywords:RNA structure prediction, RNA secondary structure, consensus structure, structural noncoding RNA
description:The secondary structure of most functional RNA molecules is strongly conserved in evolution. Prediction of these conserved structures is therefore of particular interest when studying noncoding RNAs. Moreover, structure predictions on the basis of several sequences produce much more accurate results than energy directed folding of single sequences. The RNAalifold program predicts the consensus structure for a set of aligned sequences taking into account both thermodynamic stability and sequence covariation. In this contribution, we provide a tutorial on how to install and use RNAalifold, as well as a guide on how to interpret the results.
datePublished:2007
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Book:
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isbn:
978-1-59745-514-5
978-1-58829-693-1
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name:Humana Press
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name:University of Vienna
address:
name:Department of Theoretical Chemistry, University of Vienna, Vienna
type:PostalAddress
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Person:
name:Ivo L. Hofacker
affiliation:
name:University of Vienna
address:
name:Department of Theoretical Chemistry, University of Vienna, Vienna
type:PostalAddress
type:Organization
PostalAddress:
name:Department of Theoretical Chemistry, University of Vienna, Vienna
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