We are analyzing https://link.springer.com/protocol/10.1007/978-1-4939-7187-9_9.

Title:
Quick Detection of DNase II-Type Breaks in Formalin-Fixed Tissue Sections | SpringerLink
Description:
Blunt-ended DNase II-type breaks with 5′ hydroxyls are generated in phagocytic cells of any lineage during digestion of the engulfed DNA. These breaks indicate the ongoing active phagocytic reaction. They are produced by the acid deoxyribonuclease–DNase...
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Science
Education
Telecommunications

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We don't see any clear sign of profit-making.

While many websites aim to make money, others are created to share knowledge or showcase creativity. People build websites for various reasons. This could be one of them. Link.springer.com could be getting rich in stealth mode, or the way it's monetizing isn't detectable.

Keywords {🔍}

pubmed, dna, google, scholar, didenko, article, cas, detection, breaks, minchew, protocol, dnase, methods, molecular, central, national, privacy, cookies, content, information, publish, research, damage, phagocytic, department, usa, search, tissue, sections, vladimir, biology, access, doublestrand, chapter, mol, biol, download, houston, springer, usd, personal, data, log, journal, iitype, candace, book, cells, approach, genes,

Topics {✒️}

pulsed-field gel electrophoresis month download article/chapter dnase ii-type breaks double-strand break regions double-strand dna breaks semi-artificial molecular machine steady-state kinetic analysis formalin-fixed tissue sections acid deoxyribonuclease–dnase ii detects blunt-ended 5′ privacy choices/manage cookies fixed tissue sections dna strand cleavage protocol fast detection device instant download minchew cl primary endonuclease responsible human deoxyribonuclease iibeta fluorescent probes detecting ligatable fluorescent probes grants r21 ca178965 author information authors editor information editors dna damage detection european economic area nuclear cataract caused mouse eye lens enzyme-substrate complexes grant r01 ns082553 conditions privacy policy genome-wide approach national cancer institute journal finder publish dna damage candace vaccinia dna topoisomerase accepting optional cookies topoisomerase-based approach situ ligation simplified dnase ii main content log assessing phagocytic clearance protocol minchew end resection pathways aguilera rj didenko vv didenko rights dna breaks social media tissue sections permissions reprints

Schema {🗺️}

ScholarlyArticle:
      headline:Quick Detection of DNase II-Type Breaks in Formalin-Fixed Tissue Sections
      pageEnd:119
      pageStart:113
      image:https://media.springernature.com/w153/springer-static/cover/book/978-1-4939-7187-9.jpg
      genre:
         Springer Protocols
      isPartOf:
         name:Fast Detection of DNA Damage
         isbn:
            978-1-4939-7187-9
            978-1-4939-7185-5
         type:Book
      publisher:
         name:Springer New York
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Candace L. Minchew
            affiliation:
                  name:Baylor College of Medicine
                  address:
                     name:Department of Neurosurgery, Baylor College of Medicine, Houston, USA
                     type:PostalAddress
                  type:Organization
                  name:2002 Holcombe Boulevard
                  address:
                     name:Michael E. DeBakey Veterans Affairs Medical Center, 2002 Holcombe Boulevard, Houston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Vladimir V. Didenko
            affiliation:
                  name:Baylor College of Medicine
                  address:
                     name:Department of Neurosurgery and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      keywords:Phagocytic digestion of DNA, Labeling of phagocytosis, Phagolysosomes, Clearance of cell death, Express detection of DNase II cleavage, 5′ OH DNA probes
      description:Blunt-ended DNase II-type breaks with 5′ hydroxyls are generated in phagocytic cells of any lineage during digestion of the engulfed DNA. These breaks indicate the ongoing active phagocytic reaction. They are produced by the acid deoxyribonuclease–DNase II which is the primary endonuclease responsible for DNA degradation after its engulfment. Here, we present an express approach that detects blunt-ended 5′ OH DNA breaks in fixed tissue sections. The technique is simple to perform and takes only 60 min to complete. It can be useful in studies of the clearance of dying cells in oncological, inflammatory, and autoimmune disorders.
      datePublished:2017
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
      context:https://schema.org
Book:
      name:Fast Detection of DNA Damage
      isbn:
         978-1-4939-7187-9
         978-1-4939-7185-5
Organization:
      name:Springer New York
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Baylor College of Medicine
      address:
         name:Department of Neurosurgery, Baylor College of Medicine, Houston, USA
         type:PostalAddress
      name:2002 Holcombe Boulevard
      address:
         name:Michael E. DeBakey Veterans Affairs Medical Center, 2002 Holcombe Boulevard, Houston, USA
         type:PostalAddress
      name:Baylor College of Medicine
      address:
         name:Department of Neurosurgery and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Candace L. Minchew
      affiliation:
            name:Baylor College of Medicine
            address:
               name:Department of Neurosurgery, Baylor College of Medicine, Houston, USA
               type:PostalAddress
            type:Organization
            name:2002 Holcombe Boulevard
            address:
               name:Michael E. DeBakey Veterans Affairs Medical Center, 2002 Holcombe Boulevard, Houston, USA
               type:PostalAddress
            type:Organization
      name:Vladimir V. Didenko
      affiliation:
            name:Baylor College of Medicine
            address:
               name:Department of Neurosurgery and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Neurosurgery, Baylor College of Medicine, Houston, USA
      name:Michael E. DeBakey Veterans Affairs Medical Center, 2002 Holcombe Boulevard, Houston, USA
      name:Department of Neurosurgery and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(79)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js

CDN Services {📦}

Pbgrd

4.87s.

LINK . SPRINGER . COM {}