We are analyzing https://link.springer.com/protocol/10.1007/978-1-4939-6824-4_21.

Title:
Assessing Mitochondrial Selective Autophagy in the Nematode Caenorhabditis elegans | SpringerLink
Description:
Eukaryotic cells heavily depend on ATP generated by oxidative phosphorylation (OXPHOS) within mitochondria. Besides being the main suppliers of cell’s energy, mitochondria also provide an additional compartment for a wide range of cellular processes and...
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Keywords {🔍}

pubmed, article, cas, google, scholar, mitochondrial, mitophagy, elegans, mitochondria, tavernarakis, central, protocol, caenorhabditis, research, autophagy, palikaras, chapter, cell, privacy, cookies, content, information, publish, nematode, protein, nature, search, nektarios, methods, fluorescent, biol, pink, parkin, wang, download, springer, usd, personal, data, european, log, journal, assessing, selective, book, molecular, biology, degradation, mediates, development,

Topics {✒️}

month download article/chapter n-end rule pathway hereditary early-onset parkinson pas1nb-cs-rosella plasmid pink1/parkin-dependent manner mitochondrial selective autophagy nematode caenorhabditis elegans european research council privacy choices/manage cookies chan dc caenorhabditis genetics center outer mitochondrial membrane ubiquitin-proteasome system fluorescent ph-biosensor device instant download targeting dysfunctional mitochondria tubular structure allowing expert technical support european economic area protocol palikaras author information authors editor information editors age-related diseases hops subunit vps39 wilson dm iii abou-sleiman pm reporting vacuolar turnover helmholtz zentrum münchen lifespan extension journal finder publish conditions privacy policy accepting optional cookies protocol usd 49 mitophagy mediates nektarios tavernarakis caenorhabditis elegans main content log protocol cite social media permissions reprints research resources mitochondrial network nutrient starvation parkin gene nematode strains humana press chapter log national center journal publish privacy policy

Schema {🗺️}

ScholarlyArticle:
      headline:Assessing Mitochondrial Selective Autophagy in the Nematode Caenorhabditis elegans
      pageEnd:361
      pageStart:349
      image:https://media.springernature.com/w153/springer-static/cover/book/978-1-4939-6824-4.jpg
      genre:
         Springer Protocols
      isPartOf:
         name:Mitochondria
         isbn:
            978-1-4939-6824-4
            978-1-4939-6822-0
         type:Book
      publisher:
         name:Springer New York
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Konstantinos Palikaras
            affiliation:
                  name:Foundation for Research and Technology Hellas
                  address:
                     name:Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Heraklion, Greece
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Nektarios Tavernarakis
            affiliation:
                  name:Foundation for Research and Technology Hellas
                  address:
                     name:Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Heraklion, Greece
                     type:PostalAddress
                  type:Organization
                  name:University of Crete
                  address:
                     name:Faculty of Medicine, Department of Basic Sciences, University of Crete, Heraklion, Greece
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      keywords:Ageing, Autophagosome, Autophagy, Caenorhabditis elegans , DsRed, Green Fluorescent Protein (GFP), Lysosomes, Fluorescent microscopy, Mitochondria, Mitophagy, mtRosella
      description:Eukaryotic cells heavily depend on ATP generated by oxidative phosphorylation (OXPHOS) within mitochondria. Besides being the main suppliers of cell’s energy, mitochondria also provide an additional compartment for a wide range of cellular processes and metabolic pathways. Mitochondria constantly undergo fusion/fission events and form a mitochondrial network, which is a highly dynamic, tubular structure allowing for rapid and continuous exchange of genetic material, as well as, targeting dysfunctional mitochondria for degradation through mitochondrial selective autophagy (mitophagy). Mitophagy mediates the elimination of damaged and/or superfluous organelles, maintaining mitochondrial and cellular homeostasis. In this chapter, we present two versatile, noninvasive methods, developed for monitoring in vivo mitophagy in C. elegans. These procedures enable the assessment of mitophagy in several cell types during development or under stress conditions. Investigating the role of mitophagy at the organismal level is essential for the development of therapeutic interventions against age-related diseases.
      datePublished:2017
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Book:
      name:Mitochondria
      isbn:
         978-1-4939-6824-4
         978-1-4939-6822-0
Organization:
      name:Springer New York
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Foundation for Research and Technology Hellas
      address:
         name:Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Heraklion, Greece
         type:PostalAddress
      name:Foundation for Research and Technology Hellas
      address:
         name:Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Heraklion, Greece
         type:PostalAddress
      name:University of Crete
      address:
         name:Faculty of Medicine, Department of Basic Sciences, University of Crete, Heraklion, Greece
         type:PostalAddress
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      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Konstantinos Palikaras
      affiliation:
            name:Foundation for Research and Technology Hellas
            address:
               name:Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Heraklion, Greece
               type:PostalAddress
            type:Organization
      name:Nektarios Tavernarakis
      affiliation:
            name:Foundation for Research and Technology Hellas
            address:
               name:Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Heraklion, Greece
               type:PostalAddress
            type:Organization
            name:University of Crete
            address:
               name:Faculty of Medicine, Department of Basic Sciences, University of Crete, Heraklion, Greece
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Heraklion, Greece
      name:Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Heraklion, Greece
      name:Faculty of Medicine, Department of Basic Sciences, University of Crete, Heraklion, Greece
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