We are analyzing https://link.springer.com/chapter/10.1007/3-540-27702-1_13.

Title:
Naturally Arising CD25+CD4+ Regulatory T Cells in Tumor Immunity | SpringerLink
Description:
Naturally arising regulatory T (TR) cells, represented by CD25+CD4+ TR cells, play an essential role in maintaining immunological self-tolerance. This T cell-mediated dominant control of the immune response not only inhibits the development of autoimmune disease, but...
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Schema {🗺️}

ScholarlyArticle:
      headline:Naturally Arising CD25+CD4+ Regulatory T Cells in Tumor Immunity
      pageEnd:302
      pageStart:287
      image:https://media.springernature.com/w153/springer-static/cover/book/978-3-540-27702-6.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential
         isbn:
            978-3-540-27702-6
            978-3-540-24444-8
         type:Book
      publisher:
         name:Springer Berlin Heidelberg
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:T. Nomura
            affiliation:
                  name:Kyoto University
                  address:
                     name:Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:S. Sakaguchi
            affiliation:
                  name:Kyoto University
                  address:
                     name:Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
      keywords:Foxp3 Expression, Tumor Immunity, Myelin Oligodendrocyte Glycoprotein, Autologous Tumor Cell, Neonatal Diabetes Mellitus
      description:Naturally arising regulatory T (TR) cells, represented by CD25+CD4+ TR cells, play an essential role in maintaining immunological self-tolerance. This T cell-mediated dominant control of the immune response not only inhibits the development of autoimmune disease, but also impedes effective immunosurveillance against autologous tumor cells. Attenuation of TR cell-mediated immune suppression can therefore evoke effective tumor immunity in otherwise nonresponsive animals. This common regulatory mechanism for autoimmunity and tumor immunity can be exploited when devising a novel immunotherapy for cancer.
      datePublished:2005
      isAccessibleForFree:
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Book:
      name:CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential
      isbn:
         978-3-540-27702-6
         978-3-540-24444-8
Organization:
      name:Springer Berlin Heidelberg
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Kyoto University
      address:
         name:Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
         type:PostalAddress
      name:Kyoto University
      address:
         name:Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
         type:PostalAddress
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      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:T. Nomura
      affiliation:
            name:Kyoto University
            address:
               name:Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
               type:PostalAddress
            type:Organization
      name:S. Sakaguchi
      affiliation:
            name:Kyoto University
            address:
               name:Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
      name:Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
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