We are analyzing https://link.springer.com/chapter/10.1007/978-3-642-74974-2_31.

Title:
Growth of Human Tumors in Immune-Deficient scid Mice and nude Mice | SpringerLink
Description:
The ability to grow human tumors in immune-deficient mice offers offers many research opportunities (Sharkey and Fogh 1984). In addition to simply providing a source of cells for investigation, such animals can provide models for testing therapeutic protocols...
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Keywords {🔍}

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Topics {✒️}

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Schema {🗺️}

ScholarlyArticle:
      headline:Growth of Human Tumors in Immune-Deficient scid Mice and nude Mice
      pageEnd:263
      pageStart:259
      image:https://media.springernature.com/w153/springer-static/cover/book/978-3-642-74974-2.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:The Scid Mouse
         isbn:
            978-3-642-74974-2
            978-3-642-74976-6
         type:Book
      publisher:
         name:Springer Berlin Heidelberg
         logo:
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            type:ImageObject
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      author:
            name:R. A. Phillips
            affiliation:
                  name:The Hospital for Sick Children
                  address:
                     name:Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada
                     type:PostalAddress
                  type:Organization
                  name:University of Toronto
                  address:
                     name:Department of Medical Genetics, University of Toronto, Canada
                     type:PostalAddress
                  type:Organization
            type:Person
            name:M. A. S. Jewett
            affiliation:
                  name:The Hospital for Sick Children
                  address:
                     name:Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada
                     type:PostalAddress
                  type:Organization
                  name:University of Toronto
                  address:
                     name:Department of Medical Genetics, University of Toronto, Canada
                     type:PostalAddress
                  type:Organization
                  name:The Wellesley Hospital
                  address:
                     name:Division of Urology, The Wellesley Hospital, Toronto, Canada
                     type:PostalAddress
                  type:Organization
                  name:University of Toronto
                  address:
                     name:Department of Surgery, University of Toronto, Canada
                     type:PostalAddress
                  type:Organization
            type:Person
            name:B. L. Gallie
            affiliation:
                  name:The Hospital for Sick Children
                  address:
                     name:Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada
                     type:PostalAddress
                  type:Organization
                  name:University of Toronto
                  address:
                     name:Department of Medical Genetics, University of Toronto, Canada
                     type:PostalAddress
                  type:Organization
            type:Person
      keywords:Nude Mouse, Human Tumor, Scid Mouse, Severe Combine Immunodeficiency, Human Lung Tumor
      description:The ability to grow human tumors in immune-deficient mice offers offers many research opportunities (Sharkey and Fogh 1984). In addition to simply providing a source of cells for investigation, such animals can provide models for testing therapeutic protocols (Niederkorn 1984; Brunner et al. 1987), for studying metastasis (Dore et al. 1987), and for analyzing changes associated with tumor induction and progression (Sordat and Wang 1984). Although nude mice have been used for many years to grow various human tumors, we expected that scid mice might be better recipients for growth of human tumors because the immune deficiency in scid mice is more severe than that in nude mice (Bosma et al. 1983). To test this hypothesis, we have compared the ability of various different human tumors to grow subcutaneously in nude mice and scid mice.
      datePublished:1989
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Book:
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      isbn:
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         978-3-642-74976-6
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      name:Springer Berlin Heidelberg
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         type:ImageObject
      name:The Hospital for Sick Children
      address:
         name:Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada
         type:PostalAddress
      name:University of Toronto
      address:
         name:Department of Medical Genetics, University of Toronto, Canada
         type:PostalAddress
      name:The Hospital for Sick Children
      address:
         name:Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada
         type:PostalAddress
      name:University of Toronto
      address:
         name:Department of Medical Genetics, University of Toronto, Canada
         type:PostalAddress
      name:The Wellesley Hospital
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         name:Division of Urology, The Wellesley Hospital, Toronto, Canada
         type:PostalAddress
      name:University of Toronto
      address:
         name:Department of Surgery, University of Toronto, Canada
         type:PostalAddress
      name:The Hospital for Sick Children
      address:
         name:Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada
         type:PostalAddress
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         type:PostalAddress
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      name:R. A. Phillips
      affiliation:
            name:The Hospital for Sick Children
            address:
               name:Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada
               type:PostalAddress
            type:Organization
            name:University of Toronto
            address:
               name:Department of Medical Genetics, University of Toronto, Canada
               type:PostalAddress
            type:Organization
      name:M. A. S. Jewett
      affiliation:
            name:The Hospital for Sick Children
            address:
               name:Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada
               type:PostalAddress
            type:Organization
            name:University of Toronto
            address:
               name:Department of Medical Genetics, University of Toronto, Canada
               type:PostalAddress
            type:Organization
            name:The Wellesley Hospital
            address:
               name:Division of Urology, The Wellesley Hospital, Toronto, Canada
               type:PostalAddress
            type:Organization
            name:University of Toronto
            address:
               name:Department of Surgery, University of Toronto, Canada
               type:PostalAddress
            type:Organization
      name:B. L. Gallie
      affiliation:
            name:The Hospital for Sick Children
            address:
               name:Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada
               type:PostalAddress
            type:Organization
            name:University of Toronto
            address:
               name:Department of Medical Genetics, University of Toronto, Canada
               type:PostalAddress
            type:Organization
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      name:Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada
      name:Department of Medical Genetics, University of Toronto, Canada
      name:Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada
      name:Department of Medical Genetics, University of Toronto, Canada
      name:Division of Urology, The Wellesley Hospital, Toronto, Canada
      name:Department of Surgery, University of Toronto, Canada
      name:Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada
      name:Department of Medical Genetics, University of Toronto, Canada
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