We are analyzing https://link.springer.com/chapter/10.1007/978-3-642-59953-8_8.

Title:
Functions of Tie1 and Tie2 Receptor Tyrosine Kinases in Vascular Development | SpringerLink
Description:
Vascularization of the mouse embryo is accomplished via the collaboration of two major cellular processes. Differentiation of vascular endothelial cells de novo from their precursors, called the angioblasts, has been termed vasculogenesis (Risau 1997). Somewhat...
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Keywords {🔍}

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Topics {✒️}

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Schema {🗺️}

ScholarlyArticle:
      headline:Functions of Tie1 and Tie2 Receptor Tyrosine Kinases in Vascular Development
      pageEnd:172
      pageStart:159
      image:https://media.springernature.com/w153/springer-static/cover/book/978-3-642-59953-8.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:Vascular Growth Factors and Angiogenesis
         isbn:
            978-3-642-59953-8
            978-3-642-64195-4
         type:Book
      publisher:
         name:Springer Berlin Heidelberg
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:J. Partanen
            affiliation:
                  name:Mount Sinai Hospital
                  address:
                     name:Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
                     type:PostalAddress
                  type:Organization
            type:Person
            name:D. J. Dumont
            affiliation:
                  name:University of Toronto
                  address:
                     name:Amgen and Ontario Cancer Institutes, Department of Medical Biophysics, University of Toronto, Toronto, Canada
                     type:PostalAddress
                  type:Organization
            type:Person
      keywords:Receptor Tyrosine Kinase, Vascular Development, Endothelial Cell Lineage, Tie2 Receptor, Vascular Defect
      description:Vascularization of the mouse embryo is accomplished via the collaboration of two major cellular processes. Differentiation of vascular endothelial cells de novo from their precursors, called the angioblasts, has been termed vasculogenesis (Risau 1997). Somewhat confusingly, the term vasculogenesis has also been used in a broader sense, covering all aspects of vascular development (Dumont et al. 1994; Noden 1991; Sherer 1991; Wilting and Christ 1996). Subsequent expansion of the endothelium by remodelling, migration and proliferation is called angiogenesis. Vasculogenesis is known to occur intraembryonically within the splanchnopleural and paraxial mesoderm, as well as extraembryonically in the yolk sac mesoderm, and is responsible for laying down the primitive vascular network (Pardanaud et al. 1996; Wilting and Christ 1996). Vasculogenesis is characterized by angioblast differentiation and by either the immediate aggregation of angioblast cells to give rise to endothelium, or the directed migration of these cells through the embryo to segregate eventually into vascular cords. Interestingly, angioblasts appear to have different characteristics depending on their site of origin (Pardanaud et al. 1996). Vasculogenesis both in the yolk sac and in the splanchnic mesoderm appears closely linked to haemangioblast (Pardanaud et al. 1989; Shalaby et al. 1995, 1997).
      datePublished:1999
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Book:
      name:Vascular Growth Factors and Angiogenesis
      isbn:
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         978-3-642-64195-4
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      name:Springer Berlin Heidelberg
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         type:ImageObject
      name:Mount Sinai Hospital
      address:
         name:Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
         type:PostalAddress
      name:University of Toronto
      address:
         name:Amgen and Ontario Cancer Institutes, Department of Medical Biophysics, University of Toronto, Toronto, Canada
         type:PostalAddress
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      name:J. Partanen
      affiliation:
            name:Mount Sinai Hospital
            address:
               name:Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
               type:PostalAddress
            type:Organization
      name:D. J. Dumont
      affiliation:
            name:University of Toronto
            address:
               name:Amgen and Ontario Cancer Institutes, Department of Medical Biophysics, University of Toronto, Toronto, Canada
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
      name:Amgen and Ontario Cancer Institutes, Department of Medical Biophysics, University of Toronto, Toronto, Canada
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