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Title:
Citrus Flavonoids: A Review of Past Biological Activity Against Disease | SpringerLink
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Flavonoids are common in fruits and vegetables and many function as natural antioxidants, free radical scavengers, and may also chelate pro-oxidant metals, reducing their capacity to produce free radicals (Affany et al., 1987). It has been estimated that humans...
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ScholarlyArticle:
headline:Citrus Flavonoids: A Review of Past Biological Activity Against Disease
pageEnd:116
pageStart:103
image:https://media.springernature.com/w153/springer-static/cover/book/978-1-4615-5335-9.jpg
genre:
Biomedical and Life Sciences
Biomedical and Life Sciences (R0)
isPartOf:
name:Flavonoids in the Living System
isbn:
978-1-4615-5335-9
978-1-4613-7434-3
type:Book
publisher:
name:Springer US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Antonio Montanari
affiliation:
name:Citrus Research and Education Center
address:
name:State of Florida, Department of Citrus, Citrus Research and Education Center, Lake Alfred, USA
type:PostalAddress
type:Organization
type:Person
name:Jie Chen
affiliation:
name:Citrus Research and Education Center
address:
name:State of Florida, Department of Citrus, Citrus Research and Education Center, Lake Alfred, USA
type:PostalAddress
type:Organization
type:Person
name:Wilbur Widmer
affiliation:
name:Citrus Research and Education Center
address:
name:State of Florida, Department of Citrus, Citrus Research and Education Center, Lake Alfred, USA
type:PostalAddress
type:Organization
type:Person
keywords:Human Breast Cancer Cell, Orange Juice, Grapefruit Juice, Methoxyl Group, Citrus Flavonoid
description:Flavonoids are common in fruits and vegetables and many function as natural antioxidants, free radical scavengers, and may also chelate pro-oxidant metals, reducing their capacity to produce free radicals (Affany et al., 1987). It has been estimated that humans consume 1 gram per day of flavonoids (Kuhnau et al., 1976). The majority of citrus flavonoids are flavanones bound as glycosides (Figure 1). Hesperidin, a glycoside of hesperetin, is predominant in orange and tangerine, whereas naringin and narirutin, glycosides of naringenin, are most abundant in grapefruit. Eriocitrin and hesperidin are the predominate flavonoids found in lemon and lime. Some therapeutic effects have been reported for citrus flavanoids (Fisher et al., 1982). In 1936 citrus flavonoids were reported to decrease capillary fragility and improve blood flow and were actually labeled “Vitamin P” (Rusznyak and Szent-Györgyi, 1936). But further research failed to substantiate that abnormal capillary permeability was due to a deficiency in bioflavonoids. In 1950, the Federation of American Societies for Experimental Biology recommended that the term “Vitamin P”, which had been applied to flavanoids, be discontinued (Vickery et al., 1950).
datePublished:1998
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