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Clinical Aspects of Bone Metastases in Prostate Cancer | SpringerLink
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Bone is the second most common site of metastases in human cancer. At least two-thirds of the approximately 553,400 Americans who die from cancer each year have bone metastases (Greenlee et al., 2001). Prostate, breast, and lung cancers account for at least 80% of...
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google, scholar, cancer, cas, pubmed, prostate, article, journal, bone, metastases, clinical, oncology, metastatic, urology, skeletal, patients, research, growth, treatment, metastasis, carcinoma, trial, chapter, medicine, study, factor, human, advanced, cells, prostatic, randomized, university, keller, disease, american, chung, radiotherapy, therapy, smith, phase, privacy, cookies, content, european, information, publish, biology, breast, lipton, pamidronate,
Topics {βοΈ}
2-[f-18]fluoro-2-deoxy-d-glucose 2-deoxy-2-[f-18] fluoro-d-glucose double-blind randomised trial prostate-derived growth factors weekly high-dose calcitriol radiation therapy-message conveyed advanced androgen-independent carcinoma serum prostate-specific antigen peptide-bound collagen type androgen-independent prostate cancer cross-links n-telopeptide androgen-independent cancer progression growth factor receptor placebo-controlled trial chapter tu privacy choices/manage cookies hormone refractory disease phase ii study spinal cord compression receptor antagonist atrasetan proteasome inhibitor ps-341 external radiation therapy prostate specific antigen download preview pdf stromal-epithelial interaction orchiectomy versus goserelin low dose dexamethasone symptomatic osseous metastasis increased bone resorption external beam radiotherapy advanced prostatic carcinoma population-based study relapsed/refractory disease preoperative plasma levels human prostate cancer prostatic osteoblastic factor osteoblast-stimulating factor metastatic prostate cancer circulating prostate cells pyridinium cross-links clinically localized adenocarcinoma prostate cancer metastasis metastatic bone cancer bone-targeted therapy metastatic bone disease decreases skeletal complications reducing skeletal events chapter cite symptomatic osseous metastases tyrosine kinases expressed
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ScholarlyArticle:
headline:Clinical Aspects of Bone Metastases in Prostate Cancer
pageEnd:46
pageStart:23
image:https://media.springernature.com/w153/springer-static/cover/book/978-1-4419-9129-4.jpg
genre:
Medicine
Medicine (R0)
isPartOf:
name:The Biology of Skeletal Metastases
isbn:
978-1-4419-9129-4
978-1-4613-4803-0
type:Book
publisher:
name:Springer US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Shi-Ming Tu
affiliation:
name:The University of Texas, M.D. Anderson Cancer Center
address:
name:Department of Genitourinary Medical Oncology, The University of Texas, M.D. Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:Sue-Hwa Lin
affiliation:
name:The University of Texas, M.D. Anderson Cancer Center
address:
name:Department of Genitourinary Medical Oncology, The University of Texas, M.D. Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:The University of Texas, M.D. Anderson Cancer Center
address:
name:Molecular Pathology, The University of Texas, M.D. Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
keywords:Prostate Cancer, Bone Metastasis, Radical Prostatectomy, Zoledronic Acid, Metastatic Prostate Cancer
description:Bone is the second most common site of metastases in human cancer. At least two-thirds of the approximately 553,400 Americans who die from cancer each year have bone metastases (Greenlee et al., 2001). Prostate, breast, and lung cancers account for at least 80% of the skeletal metastases. Tumors arising in the prostate and breast are particularly prone to disseminate to bone; up to 85% of patients with these cancers have evidence of bone metastases at autopsy. Carcinomas of the lung, thyroid, and kidney also commonly spread to the bone (30β40%). However, tumors of the gastrointestinal tract rarely metastasize to the bone (5%) (Galasko, 1986).
datePublished:2004
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name:Springer US
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name:The University of Texas, M.D. Anderson Cancer Center
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name:Molecular Pathology, The University of Texas, M.D. Anderson Cancer Center, Houston, USA
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name:Department of Genitourinary Medical Oncology, The University of Texas, M.D. Anderson Cancer Center, Houston, USA
name:Department of Genitourinary Medical Oncology, The University of Texas, M.D. Anderson Cancer Center, Houston, USA
name:Molecular Pathology, The University of Texas, M.D. Anderson Cancer Center, Houston, USA
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