We are analyzing https://link.springer.com/article/10.1385/ir:36:1:247.

Title:
Human tumor-derived vs dendritic cell-derived exosomes have distinct biologic roles and molecular profiles | Immunologic Research
Description:
Microvesicles (MV) or exosomes are produced and secreted by tumor and normal cells. The molecular profile and functions of tumor-derived vs dendritic cell (DC)-derived MV are distinct. The former express death ligands and mediate apoptosis of activated T cells. The latter promote CD4+T cell proliferation and may play a role in regulating T cell responses. Serving as intercellular communication networks, tumor-derived MV contribute to tumor escape, while DC-derived MV drive and regulate immune response.
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28 years and 1 months (reg. 1997-05-29).

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Keywords {🔍}

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Topics {✒️}

myeloid-derived suppressor cells dendritic cell-derived exosomes month download article/chapter t-cell signaling defects dendritic cell-derived dendritic cells cells apoptosis access fasl+membraneous vesicles isolated human tumor-derived tumor-derived mv contribute express death ligands dendritic cell related subjects dc-derived mv drive tumor-infiltrating lymphocytes taylor dd cell-free vaccine full article pdf established murine tumors privacy choices/manage cookies tumor cell secretion fasl-bearing microvesicles tumor-derived exosomes immune cells normal cells pittsburgh cancer institute tumour-derived exosomes article wieckowski european economic area intercellular communication networks plasma membrane vesicles plasma membrane fragments plasma membrane activities future therapeutic interventions conditions privacy policy regulate immune response host immune system accepting optional cookies cells check access instant access article log molecular profiles published gercel-taylor distinct biologic roles tumor-derived main content log tumor vaccine whiteside tl article cite

Questions {❓}

Tumour-derived exosomes or microvesicles: another mechanism of tumour escape from the host immune system?

Schema {🗺️}

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         description:Microvesicles (MV) or exosomes are produced and secreted by tumor and normal cells. The molecular profile and functions of tumor-derived vs dendritic cell (DC)-derived MV are distinct. The former express death ligands and mediate apoptosis of activated T cells. The latter promote CD4+T cell proliferation and may play a role in regulating T cell responses. Serving as intercellular communication networks, tumor-derived MV contribute to tumor escape, while DC-derived MV drive and regulate immune response.
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