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Title:
Iron Deficiency, Cognitive Functions, and Neurobehavioral Disorders in Children | Journal of Molecular Neuroscience
Description:
More than 25% of the world’s population is affected by anemia, of which more than 50% suffers from iron deficiency anemia (IDA). Children below 7 years of age are the population group that is most vulnerable to iron deficiency. Iron is an essential element in brain metabolism. Iron deficiency can cause changes in neurotransmitter homeostasis, decrease myelin production, impair synaptogenesis, and decline the function of the basal ganglia. Therefore, IDA adversely affects cognitive functions and psychomotor development. Research has shown that iron deficiency is a frequent comorbidity in attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder. Iron deficiency may also induce or exacerbate deficiency of other essential nutrients, which may have a negative impact on the developing brain and other organs in infants. Many nations of the world have programs to control IDA based on the use of iron supplementation, intake of fortified food and drinks, improved food safety, and monitoring of dietary diversity. Based on the current recommendations of the World Health Organization on cost-effectiveness (WHO-CHOICE), iron fortification and iron supplementation programs can be considered cost-effective or even highly cost-effective in most countries of the world to averting cognitive impairment.
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Keywords {🔍}
iron, pubmed, article, google, scholar, deficiency, cas, children, nutr, development, anemia, cognitive, health, supplementation, central, disorder, brain, autism, systematic, review, httpsdoiorgs, effect, psychomotor, world, effects, clin, function, content, bjørklund, spectrum, food, med, childhood, research, disorders, age, metaanalysis, httpsdoiorg, rev, early, pediatr, wang, privacy, cookies, analysis, data, journal, semenova, infants, developmental,
Topics {✒️}
multi-parametric biomarker profiles month download article/chapter yuliya semenova attention-deficit/hyperactivity disorder attention deficit/hyperactivity disorder attention-deficit hyperactivity disorder geir bjørklund long-term developmental outcome author correspondence autism spectrum disorder primary-school-aged children monica daniela doşa young school-aged children full article pdf safety research group psychomotor development tests improving psychomotor development article pivina infant psychomotor development developmental iron deficiency privacy choices/manage cookies molecular neuroscience aims check access erikson km 1159/000448934 grantham-mcgregor global developmental delay instant access semey medical university impaired cognitive development disease attributable adhd long-term deficits endogenous human capital georgieff mk ilsi research foundation additional information publisher averting cognitive impairment iron deficiency anemia iron-deficiency anemia long-term brain early childhood anemia preventing childhood anemia adolescent intellectual development health technology assessment universal health coverage neurobehavioral disorders infant motor development european economic area decrease myelin production improved food safety
Questions {❓}
- Cortese S, Angriman M, Lecendreux M, Konofal E (2012a) Iron and attention deficit/hyperactivity disorder: What is the empirical evidence so far?
- Larson LM, Phiri KS, Pasricha SR (2017) Iron and cognitive development: what is the evidence?
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headline:Iron Deficiency, Cognitive Functions, and Neurobehavioral Disorders in Children
description:More than 25% of the world’s population is affected by anemia, of which more than 50% suffers from iron deficiency anemia (IDA). Children below 7 years of age are the population group that is most vulnerable to iron deficiency. Iron is an essential element in brain metabolism. Iron deficiency can cause changes in neurotransmitter homeostasis, decrease myelin production, impair synaptogenesis, and decline the function of the basal ganglia. Therefore, IDA adversely affects cognitive functions and psychomotor development. Research has shown that iron deficiency is a frequent comorbidity in attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder. Iron deficiency may also induce or exacerbate deficiency of other essential nutrients, which may have a negative impact on the developing brain and other organs in infants. Many nations of the world have programs to control IDA based on the use of iron supplementation, intake of fortified food and drinks, improved food safety, and monitoring of dietary diversity. Based on the current recommendations of the World Health Organization on cost-effectiveness (WHO-CHOICE), iron fortification and iron supplementation programs can be considered cost-effective or even highly cost-effective in most countries of the world to averting cognitive impairment.
datePublished:2019-02-18T00:00:00Z
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description:More than 25% of the world’s population is affected by anemia, of which more than 50% suffers from iron deficiency anemia (IDA). Children below 7 years of age are the population group that is most vulnerable to iron deficiency. Iron is an essential element in brain metabolism. Iron deficiency can cause changes in neurotransmitter homeostasis, decrease myelin production, impair synaptogenesis, and decline the function of the basal ganglia. Therefore, IDA adversely affects cognitive functions and psychomotor development. Research has shown that iron deficiency is a frequent comorbidity in attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder. Iron deficiency may also induce or exacerbate deficiency of other essential nutrients, which may have a negative impact on the developing brain and other organs in infants. Many nations of the world have programs to control IDA based on the use of iron supplementation, intake of fortified food and drinks, improved food safety, and monitoring of dietary diversity. Based on the current recommendations of the World Health Organization on cost-effectiveness (WHO-CHOICE), iron fortification and iron supplementation programs can be considered cost-effective or even highly cost-effective in most countries of the world to averting cognitive impairment.
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