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Title:
Nanotechnology in stem cell research and therapy | Journal of Nanoparticle Research
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The ability for stem cell therapy in degenerative diseases and the replacement of organs has shown promising results in preclinical research. However, its therapeutic use remains limited even after several years of study. There is currently no single product or protocol based on stem cell therapy. Nanotechnology has shown tremendous potential and gained momentum in stem cell research and therapy due to its several characteristics like tunnel effects, quantum size effects, scale, and surface effects. Its importance is now being recognized specifically in the conformity, replication, and differentiation of stem cells. It has always been an area of interesting study for tissue engineering and regenerative medicine. Although there are many possibilities that nanotechnology may improve cell therapy and stem cell technology, still there are many cytotoxic threats, affecting the viability, stem cell differentiation, etc., that are associated. In this paper, some of the advancements and viewpoints on the use of nanotechnology in stem cell research and stem cell therapy have been discussed along with the application of nanoparticle in isolation tracking, regulation, and enhancing retention of stem cells. The article also discusses the problems, implementations, and challenges in the field that would strengthen the viewpoint and open up new directions/paths for future studies in the field.
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article, google, scholar, cas, stem, cells, cell, delivery, nanoparticles, gene, mesenchymal, therapy, human, nanotechnology, magnetic, differentiation, httpsdoiorg, mater, research, tissue, engineering, pharm, med, nanomedicine, drug, sci, imaging, res, wang, zhang, vivo, chem, nanoparticle, int, nature, httpsdoiorgs, efficient, effects, liu, rev, quantum, medicine, tracking, cancer, biotechnol, nat, dendrimers, applications, bone, rat,
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org/content/56/supplement_3/1206/tab-article-info kesharwani 6b01401/asset/images/large/nn-2016-01401d_0006 5b00153/asset/images/large/mp-2015-00153c_0010 stem cell-based therapies month download article/chapter gene-coated plga nanoparticles surface-modified fe3o4 spherical cationic solid-lipid nanoparticles iron oxide nanoparticles stem cell-based therapy stem cell biology silica-coated magnetic nanoparticles jetpei/gd-dtpa complexes /sites/default/files/national_guidelines_stemcellresearch-2017 rod-shaped magnetic nanoparticles early-stage apoptotic cells surface-conjugated synthetic nanoparticles plla/pcl hybrid nanoscaffold drug-coated magnetic nanoparticles electroporation-induced adverse effects transplanted bone marrow nanoparticle-based drug delivery gene/vaccine delivery vectors nanoscaffold-coated model bioreactor medical-devices/oclc/959875453 spitalieri mesenchymal stem cells stem cell research mitochondrial targeting dendrimer stem cell therapy neural stem cells hematopoietic stem cells embryonic stem cells dendrimer-based nanovectors stem cell imaging solid lipid nanoparticles stem cell differentiation stem-cell competition stem cell engraftment efficient sirna delivery nanoparticle-enhanced generation multimodal silica nanoparticles induce cns injury calcium-sensing receptor transplant injection device magnetically labeled cells cell-substrate interactions article bharti dimensional nanoscaffold coated efficient gene delivery stem cell technology
Questions {β}
- Chaplot SP, Rupenthal ID (2014) Dendrimers for gene delivery - a potential approach for ocular therapy?
- Farzamfar S et al (2019) Will nanotechnology bring new hope for stem cell therapy?
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