We are analyzing https://link.springer.com/article/10.1007/s10439-005-9006-3.

Title:
Nanotechnology for Cell–Substrate Interactions | Annals of Biomedical Engineering
Description:
In the pursuit to understand the interaction between cells and their underlying substrates, the life sciences are beginning to incorporate micro- and nanotechnology-based tools to probe and measure cells. The development of these tools portends endless possibilities for new insights into the fundamental relationships between cells and their surrounding microenvironment that underlie the physiology of human tissue. Here, we review techniques and tools that have been used to study how a cell responds to the physical factors in its environment. We also discuss unanswered questions that could be addressed by these approaches to better elucidate the molecular processes and mechanical forces that dominate the interactions between cells and their physical scaffolds.
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Keywords {🔍}

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Topics {✒️}

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Questions {❓}

Patterning self-assembled monolayers using microcontact printing: A new technology for biosensors?

Schema {🗺️}

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         headline:Nanotechnology for Cell–Substrate Interactions
         description:In the pursuit to understand the interaction between cells and their underlying substrates, the life sciences are beginning to incorporate micro- and nanotechnology-based tools to probe and measure cells. The development of these tools portends endless possibilities for new insights into the fundamental relationships between cells and their surrounding microenvironment that underlie the physiology of human tissue. Here, we review techniques and tools that have been used to study how a cell responds to the physical factors in its environment. We also discuss unanswered questions that could be addressed by these approaches to better elucidate the molecular processes and mechanical forces that dominate the interactions between cells and their physical scaffolds.
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            Integrins
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            Classical Mechanics
            Biochemistry
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      description:In the pursuit to understand the interaction between cells and their underlying substrates, the life sciences are beginning to incorporate micro- and nanotechnology-based tools to probe and measure cells. The development of these tools portends endless possibilities for new insights into the fundamental relationships between cells and their surrounding microenvironment that underlie the physiology of human tissue. Here, we review techniques and tools that have been used to study how a cell responds to the physical factors in its environment. We also discuss unanswered questions that could be addressed by these approaches to better elucidate the molecular processes and mechanical forces that dominate the interactions between cells and their physical scaffolds.
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         Extracellular Matrix
         Focal Adhesions
         Integrins
         Mechanotransduction
         Micropatterning
         Nanotopology
         Self-Assembled Monolayers (SAMs)
         Traction Forces
         Biomedicine
         general
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         Biological and Medical Physics
         Biophysics
         Classical Mechanics
         Biochemistry
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      affiliation:
            name:University of Pennsylvania
            address:
               name:Department of Bioengineering, University of Pennsylvania, Philadelphia, USA
               type:PostalAddress
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            address:
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