We are analyzing https://link.springer.com/article/10.1007/s100720050010.

Title:
Psychiatric symptoms as late onset of Wilson's disease: neuroradiological findings, clinical features and treatment | Neurological Sciences
Description:
Neurological Sciences - We describe a case of Wilson
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28 years and 1 months (reg. 1997-05-29).

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Keywords {🔍}

article, disease, wilsons, privacy, cookies, content, journal, information, publish, search, neurological, psychiatric, access, torino, data, log, research, late, onset, clinical, treatment, case, keller, torta, lagget, disorder, agents, hyperintensity, images, part, chapter, discover, springer, optional, personal, parties, policy, find, track, italian, sciences, symptoms, neuroradiological, findings, features, report, cite, crasto, bergamasco, explore,

Topics {✒️}

interpersonal psychotherapy month download article/chapter antidepressive agents major depressive disorder privacy choices/manage cookies neurological sciences aims ceruloplasmin serum level late psychiatric onset full article pdf european economic area scope submit manuscript emotional lability occurred serum copper levels kayser-fleischer ring d2-dopaminergic receptors basal ganglia low-copper diet conditions privacy policy extrapyramidal hand tremor check access instant access t1-weighted images t2-weighted images antidepressant agents psychiatric symptoms accepting optional cookies related subjects neurological type wilson journal finder publish privacy policy personal data books a 72-weighted images neurological signs article log optional cookies manage preferences bergamasco department subscription content similar content late onset data protection essential cookies cookies skip extrapyramidal signs institution subscribe article cite article keller journal publish italian journal

Schema {🗺️}

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         headline:Psychiatric symptoms as late onset of Wilson's disease: neuroradiological findings, clinical features and treatment
         description: We describe a case of Wilson's disease with late psychiatric onset. Major depressive disorder was the first clinical manifestation at the age of 38 years. After pharmacotherapy with antidepressive agents, a manic episode was oberseved. Extrapyramidal hand tremor and micrography were the first neurological signs. Emotional lability occurred during worsening of extrapyramidal signs. Diagnosis was based on urinary and serum copper levels, ceruloplasmin serum level, Kayser-Fleischer ring, and liver biopsy that detected cirrhosis. Magnetic resonance imaging revealed basal ganglia hyperintensity on T1-weighted images, and hypodensity in the central part and hyperintensity in the peripheral part of the lentiform nucleus on 72-weighted images. Hyperintensity on T2-weighted images was also observed in the dorsal part of the midbrain. 123I-iodobenzamide single photon emission computed tomography (IBZM-SPECT) detected a normal distribution of the drug in the brain, with better signal in the right side and deficit of D2-dopaminergic receptors in the basal ganglia, Abnormal manganese erythrocyte level was observed. Treatment was based on penicillamine, zinc salts, low-copper diet, antidepressant agents, interpersonal psychotherapy and neurorehabilitation.
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            Key words Hepatolenticular degeneration
            Affective disorders
            Magnetic resonance imaging
            Antidepressive agents
            Interpersonal psychotherapy
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            Neurosurgery
            Psychiatry
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      headline:Psychiatric symptoms as late onset of Wilson's disease: neuroradiological findings, clinical features and treatment
      description: We describe a case of Wilson's disease with late psychiatric onset. Major depressive disorder was the first clinical manifestation at the age of 38 years. After pharmacotherapy with antidepressive agents, a manic episode was oberseved. Extrapyramidal hand tremor and micrography were the first neurological signs. Emotional lability occurred during worsening of extrapyramidal signs. Diagnosis was based on urinary and serum copper levels, ceruloplasmin serum level, Kayser-Fleischer ring, and liver biopsy that detected cirrhosis. Magnetic resonance imaging revealed basal ganglia hyperintensity on T1-weighted images, and hypodensity in the central part and hyperintensity in the peripheral part of the lentiform nucleus on 72-weighted images. Hyperintensity on T2-weighted images was also observed in the dorsal part of the midbrain. 123I-iodobenzamide single photon emission computed tomography (IBZM-SPECT) detected a normal distribution of the drug in the brain, with better signal in the right side and deficit of D2-dopaminergic receptors in the basal ganglia, Abnormal manganese erythrocyte level was observed. Treatment was based on penicillamine, zinc salts, low-copper diet, antidepressant agents, interpersonal psychotherapy and neurorehabilitation.
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         Key words Hepatolenticular degeneration
         Affective disorders
         Magnetic resonance imaging
         Antidepressive agents
         Interpersonal psychotherapy
         Neurology
         Neuroradiology
         Neurosurgery
         Psychiatry
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