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Title:
Alternative splicing of transcription factors in plant responses to low temperature stress: mechanisms and functions | Planta
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Transcription factors play a central role in the gene regulatory networks that mediate various aspects of plant developmental processes and responses to environmental changes. Therefore, their activities are elaborately regulated at multiple steps. In particular, accumulating evidence illustrates that post-transcriptional control of mRNA metabolism is a key molecular scheme that modulates the transcription factor activities in plant responses to temperature fluctuations. Transcription factors have a modular structure consisting of distinct protein domains essential for DNA binding, dimerization, and transcriptional regulation. Alternative splicing produces multiple proteins having different structural domain compositions from a single transcription factor gene. Recent studies have shown that alternative splicing of some transcription factor genes generates small interfering peptides (siPEPs) that negatively regulate the target transcription factors via peptide interference (PEPi), constituting self-regulatory circuits in plant cold stress response. A number of splicing factors, which are involved in RNA binding, splice site selection, and spliceosome assembly, are also affected by temperature fluctuations, supporting the close association of alternative splicing of transcription factors with plant responses to low temperatures. In this review, we summarize recent progress on the temperature-responsive alternative splicing of transcription factors in plants with emphasis on the siPEP-mediated PEPi mechanism.
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Keywords {๐}
splicing, alternative, article, plant, google, scholar, transcription, pubmed, cas, gene, arabidopsis, factors, factor, genes, temperature, protein, splice, plants, proteins, regulation, seo, cell, responses, temperatures, low, expression, transcriptional, functional, stress, park, binding, variants, domains, sipeps, regulatory, cold, activities, response, conditions, transcripts, hfr, nmd, kim, circadian, clock, regulated, domain, growth, palusa, zpr,
Topics {โ๏ธ}
pre3/bhlh135/atbs1/tmo7 gene org/pb2006/public/p03/p03015 pre3/bhlh135/atbs1/tmo7 plant-specific zinc finger-homeobox conserved snw/ski-interacting protein serine/arginine-rich protein family plant serine/arginine-rich proteins c-repeat binding factor arabidopsis serine/arginine-rich proteins truncated ptrsnd1-a2 isoform hd-zip iii proteins sr-related protein-coding genes hd-zip iii activity snd1-a2 isoform suppresses phb-1dย รย zpr3-1d plants article download pdf serine/arginine-rich upf typeii mads-box genes chung-mo park tetraploid capsella bursa-pastoris arg/ser-rich domain high-throughput sequencing techniques negative signaling elements diversify dna-binding specificities helix-loop-helix idd14 atypical helix-loop-helix full-length cdna sequences mads-box gene homologous basic dna-binding domain full-size transcription factors lack dna-binding domains abiotic stress-responsive genes stress-upregulated nuclear protein nonsense-mediated mrna decay methyl jasmonate pre-treatment proteinโprotein interaction domain hd-zip iii downstream targets cold-regulated pre-mrna splicing factor cold-responsive gene regulation temperature-responsive splicing factors fine-tuning plant response encode myb domain temperature-responsive alternative splicing lacks dna-binding mini zinc finger putative zinc finger transcription factor families alternative pre-mrna splicing serine/arginine-rich
Questions {โ}
- Baxevanis AD, Vinson CR (1993) Interactions of coiled coils in transcription factors: where is the specificity?
- Kalyna M, Barta A (2004) A plethora of plant serine/arginine-rich proteins: redundancy or evolution of novel gene functions?
- Rebbapragada I, Lykke-Andersen J (2009) Execution of nonsense-mediated mRNA decay: what defines a substrate?
Schema {๐บ๏ธ}
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headline:Alternative splicing of transcription factors in plant responses to low temperature stress: mechanisms and functions
description:Transcription factors play a central role in the gene regulatory networks that mediate various aspects of plant developmental processes and responses to environmental changes. Therefore, their activities are elaborately regulated at multiple steps. In particular, accumulating evidence illustrates that post-transcriptional control of mRNA metabolism is a key molecular scheme that modulates the transcription factor activities in plant responses to temperature fluctuations. Transcription factors have a modular structure consisting of distinct protein domains essential for DNA binding, dimerization, and transcriptional regulation. Alternative splicing produces multiple proteins having different structural domain compositions from a single transcription factor gene. Recent studies have shown that alternative splicing of some transcription factor genes generates small interfering peptides (siPEPs) that negatively regulate the target transcription factors via peptide interference (PEPi), constituting self-regulatory circuits in plant cold stress response. A number of splicing factors, which are involved in RNA binding, splice site selection, and spliceosome assembly, are also affected by temperature fluctuations, supporting the close association of alternative splicing of transcription factors with plant responses to low temperatures. In this review, we summarize recent progress on the temperature-responsive alternative splicing of transcription factors in plants with emphasis on the siPEP-mediated PEPi mechanism.
datePublished:2013-04-28T00:00:00Z
dateModified:2013-04-28T00:00:00Z
pageStart:1415
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keywords:
Alternative splicing
Arabidopsis
Cold stress
Peptide interference (PEPi)
Small interfering peptide (siPEP)
Splicing factor
Transcription factor
Plant Sciences
Agriculture
Ecology
Forestry
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headline:Alternative splicing of transcription factors in plant responses to low temperature stress: mechanisms and functions
description:Transcription factors play a central role in the gene regulatory networks that mediate various aspects of plant developmental processes and responses to environmental changes. Therefore, their activities are elaborately regulated at multiple steps. In particular, accumulating evidence illustrates that post-transcriptional control of mRNA metabolism is a key molecular scheme that modulates the transcription factor activities in plant responses to temperature fluctuations. Transcription factors have a modular structure consisting of distinct protein domains essential for DNA binding, dimerization, and transcriptional regulation. Alternative splicing produces multiple proteins having different structural domain compositions from a single transcription factor gene. Recent studies have shown that alternative splicing of some transcription factor genes generates small interfering peptides (siPEPs) that negatively regulate the target transcription factors via peptide interference (PEPi), constituting self-regulatory circuits in plant cold stress response. A number of splicing factors, which are involved in RNA binding, splice site selection, and spliceosome assembly, are also affected by temperature fluctuations, supporting the close association of alternative splicing of transcription factors with plant responses to low temperatures. In this review, we summarize recent progress on the temperature-responsive alternative splicing of transcription factors in plants with emphasis on the siPEP-mediated PEPi mechanism.
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dateModified:2013-04-28T00:00:00Z
pageStart:1415
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keywords:
Alternative splicing
Arabidopsis
Cold stress
Peptide interference (PEPi)
Small interfering peptide (siPEP)
Splicing factor
Transcription factor
Plant Sciences
Agriculture
Ecology
Forestry
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