We are analyzing https://link.springer.com/article/10.1007/s00335-009-9204-7.

Title:
The gastrointestinal microbiome: a malleable, third genome of mammals | Mammalian Genome
Description:
The nonpathogenic, mutualistic bacteria of the mammalian gastrointestinal tract provide a number of benefits to the host. Recent reports have shown how the aggregate genomes of gastrointestinal bacteria provide novel benefits by functioning as the third major genome in mammals along with the nuclear and mitochondrial genomes. Consequently, efforts are underway to elucidate the complexity of the organisms comprising the unique ecosystem of the gastrointestinal tract, as well as those associated with other epidermal surfaces. The current knowledge of the gastrointestinal microbiome, its relationship to human health and disease with a particular focus on mammalian physiology, and efforts to alter its composition as a novel therapeutic approach are reviewed.
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Keywords {🔍}

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Topics {✒️}

month download article/chapter bifidobacterium longum subsp acclimatizing germ-free rats irritable bowel syndrome gram-positive probiotic bacteria inflammatory bowel disease human-bacteroides thetaiotaomicron symbiosis specific butyrate-producing bacteria akkermans-van vliet wm microbiome-mammalian metabolic interactions diet-induced metabolic improvements lactic acid bacteria gene-centric metagenomics full article pdf mouse metabolic phenotypes metabolic profiling reveals anti-inflammatory properties germ-free mice de visser jagm de vos wm privacy choices/manage cookies host-specific insight infantis reveals adaptations helicobacter hepaticus-infected chronic mucosal inflammation bruno-barcena jm rag2-deficient mice smad3-deficient mice helicobacter hepaticus infection health-related quality genetic characteristics mammalian gut flora human subjects consuming core gut microbiome gut microbiome modulates normal microbial flora human skin microbiome human salivary microbiome human microbiome project turnbaugh pj lactobacillus jensenii engineered autistic spectrum disorders lactobacillus rhamnosus dr20 gastrointestinal bacteria provide fungal microbiota increase mammalian blood metabolites host immune response metabolic cross-feeding induced pancreatic insufficiency human gut microbiomes

Questions {❓}

Implications for Crohn’s disease?
O’Keefe SJ, Chung D, Mahmoud N, Sepulveda AR, Manafe M et al (2007) Why do African Americans get more colon cancer than Native Africans?

Schema {🗺️}

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         headline:The gastrointestinal microbiome: a malleable, third genome of mammals
         description:The nonpathogenic, mutualistic bacteria of the mammalian gastrointestinal tract provide a number of benefits to the host. Recent reports have shown how the aggregate genomes of gastrointestinal bacteria provide novel benefits by functioning as the third major genome in mammals along with the nuclear and mitochondrial genomes. Consequently, efforts are underway to elucidate the complexity of the organisms comprising the unique ecosystem of the gastrointestinal tract, as well as those associated with other epidermal surfaces. The current knowledge of the gastrointestinal microbiome, its relationship to human health and disease with a particular focus on mammalian physiology, and efforts to alter its composition as a novel therapeutic approach are reviewed.
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         Irritable Bowel Syndrome
         Microbiota Composition
         Bifidobacterium Longum
         Host Genetic
         Cell Biology
         Animal Genetics and Genomics
         Human Genetics
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