JHOONLINE . BIOMEDCENTRAL . COM {
}
Title:
A comprehensive data mining study shows that most nuclear receptors act as newly proposed homeostasis-associated molecular pattern receptors | Journal of Hematology & Oncology | Full Text
Description:
Background Nuclear receptors (NRs) can regulate gene expression; therefore, they are classified as transcription factors. Despite the extensive research carried out on NRs, still several issues including (1) the expression profile of NRs in human tissues, (2) how the NR expression is modulated during atherosclerosis and metabolic diseases, and (3) the overview of the role of NRs in inflammatory conditions are not fully understood. Methods To determine whether and how the expression of NRs are regulated in physiological/pathological conditions, we took an experimental database analysis to determine expression of all 48 known NRs in 21 human and 17 murine tissues as well as in pathological conditions. Results We made the following significant findings: (1) NRs are differentially expressed in tissues, which may be under regulation by oxygen sensors, angiogenesis pathway, stem cell master regulators, inflammasomes, and tissue hypo-/hypermethylation indexes; (2) NR sequence mutations are associated with increased risks for development of cancers and metabolic, cardiovascular, and autoimmune diseases; (3) NRs have less tendency to be upregulated than downregulated in cancers, and autoimmune and metabolic diseases, which may be regulated by inflammation pathways and mitochondrial energy enzymes; and (4) the innate immune sensor inflammasome/caspase-1 pathway regulates the expression of most NRs. Conclusions Based on our findings, we propose a new paradigm that most nuclear receptors are anti-inflammatory homeostasis-associated molecular pattern receptors (HAMPRs). Our results have provided a novel insight on NRs as therapeutic targets in metabolic diseases, inflammations, and malignancies.
Website Age:
25 years and 10 months (reg. 1999-08-06).
Matching Content Categories {📚}
- Social Networks
- Education
- Science
Content Management System {📝}
What CMS is jhoonline.biomedcentral.com built with?
Custom-built
No common CMS systems were detected on Jhoonline.biomedcentral.com, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of jhoonline.biomedcentral.com audience?
🚄 Respectable Traffic: 10k - 20k visitors per month
Based on our best estimate, this website will receive around 10,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Jhoonline.biomedcentral.com Make Money? {💸}
Display Ads {🎯}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (3)
yourbow.com, google.com, doceree.comHow Much Does Jhoonline.biomedcentral.com Make? {💰}
Display Ads {🎯}
$190 per month
Our calculations suggest that Jhoonline.biomedcentral.com earns between $126 and $347 monthly online from display advertisements.
Keywords {🔍}
cookies, bmc, receptors, privacy, data, nuclear, family, domain, page, correlation, nlr, card, optional, content, personal, parties, policy, information, manage, journal, hematology, oncology, tissues, inflammasome, genes, highly, expressed, protein, article, contact, editing, authors, choice, essential, make, site, function, advertising, personalisation, usage, analysis, social, media, accepting, consent, processing, including, transfers, european, economic,
Topics {✒️}
article page journal nucleotide-binding oligomerization domain authors scientific editing privacy choices/manage cookies bmc nuclear receptors act european economic area newly proposed homeostasis state privacy rights correlation tiers show statistically significant correlation accepting optional cookies 1756-8722 contact manage preferences card domain nuclear receptors personal data inflammasome genes data protection optional cookies essential cookies cookies skip account journal cookies policy privacy policy privacy statement usage analysis social media varying standards upstream regulators downstream targets lymph node general enquiries preference centre springer nature content human tissues receptors 1/2/3/4 choices privacy correlation tissues choice make site function advertising personalisation consent processing
Schema {🗺️}
WebPage:
mainEntity:
headline:A comprehensive data mining study shows that most nuclear receptors act as newly proposed homeostasis-associated molecular pattern receptors
description:Nuclear receptors (NRs) can regulate gene expression; therefore, they are classified as transcription factors. Despite the extensive research carried out on NRs, still several issues including (1) the expression profile of NRs in human tissues, (2) how the NR expression is modulated during atherosclerosis and metabolic diseases, and (3) the overview of the role of NRs in inflammatory conditions are not fully understood. To determine whether and how the expression of NRs are regulated in physiological/pathological conditions, we took an experimental database analysis to determine expression of all 48 known NRs in 21 human and 17 murine tissues as well as in pathological conditions. We made the following significant findings: (1) NRs are differentially expressed in tissues, which may be under regulation by oxygen sensors, angiogenesis pathway, stem cell master regulators, inflammasomes, and tissue hypo-/hypermethylation indexes; (2) NR sequence mutations are associated with increased risks for development of cancers and metabolic, cardiovascular, and autoimmune diseases; (3) NRs have less tendency to be upregulated than downregulated in cancers, and autoimmune and metabolic diseases, which may be regulated by inflammation pathways and mitochondrial energy enzymes; and (4) the innate immune sensor inflammasome/caspase-1 pathway regulates the expression of most NRs. Based on our findings, we propose a new paradigm that most nuclear receptors are anti-inflammatory homeostasis-associated molecular pattern receptors (HAMPRs). Our results have provided a novel insight on NRs as therapeutic targets in metabolic diseases, inflammations, and malignancies.
datePublished:2017-10-24T00:00:00Z
dateModified:2017-10-24T00:00:00Z
pageStart:1
pageEnd:41
license:http://creativecommons.org/publicdomain/zero/1.0/
sameAs:https://doi.org/10.1186/s13045-017-0526-8
keywords:
Nuclear receptors (NRs)
Homeostasis-associated molecular pattern receptors
Atherosclerosis
Metabolic disease
Cardiovascular disease
Oncology
Hematology
Cancer Research
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig1_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig2_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig3_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig4_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig5_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig6_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig7_HTML.gif
isPartOf:
name:Journal of Hematology & Oncology
issn:
1756-8722
volumeNumber:10
type:
Periodical
PublicationVolume
publisher:
name:BioMed Central
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Luqiao Wang
affiliation:
name:The Second Affiliated Hospital of Nanchang University
address:
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:The First Affiliated Hospital of Kunming Medical University
address:
name:Department of Cardiovascular Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, China
type:PostalAddress
type:Organization
type:Person
name:Gayani Nanayakkara
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Qian Yang
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Xijing Hospital and Fourth Military Medical University
address:
name:Department of Ultrasound, Xijing Hospital and Fourth Military Medical University, Xi’an, China
type:PostalAddress
type:Organization
type:Person
name:Hongmei Tan
affiliation:
name:Sun Yat-sen University
address:
name:Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
type:PostalAddress
type:Organization
type:Person
name:Charles Drummer
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Yu Sun
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Ying Shao
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Hangfei Fu
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Ramon Cueto
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Huimin Shan
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Teodoro Bottiglieri
affiliation:
name:Baylor Research Institute
address:
name:Institute of Metabolic Disease, Baylor Research Institute, Dallas, USA
type:PostalAddress
type:Organization
type:Person
name:Ya-feng Li
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Candice Johnson
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:William Y. Yang
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Fan Yang
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Yanjie Xu
affiliation:
name:The Second Affiliated Hospital of Nanchang University
address:
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
type:PostalAddress
type:Organization
type:Person
name:Hang Xi
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Weiqing Liu
affiliation:
name:The First Affiliated Hospital of Kunming Medical University
address:
name:Department of Cardiovascular Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, China
type:PostalAddress
type:Organization
type:Person
name:Jun Yu
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Eric T. Choi
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Department of Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Xiaoshu Cheng
affiliation:
name:The Second Affiliated Hospital of Nanchang University
address:
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Hong Wang
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Xiaofeng Yang
url:http://orcid.org/0000-0002-6854-6195
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:1
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:A comprehensive data mining study shows that most nuclear receptors act as newly proposed homeostasis-associated molecular pattern receptors
description:Nuclear receptors (NRs) can regulate gene expression; therefore, they are classified as transcription factors. Despite the extensive research carried out on NRs, still several issues including (1) the expression profile of NRs in human tissues, (2) how the NR expression is modulated during atherosclerosis and metabolic diseases, and (3) the overview of the role of NRs in inflammatory conditions are not fully understood. To determine whether and how the expression of NRs are regulated in physiological/pathological conditions, we took an experimental database analysis to determine expression of all 48 known NRs in 21 human and 17 murine tissues as well as in pathological conditions. We made the following significant findings: (1) NRs are differentially expressed in tissues, which may be under regulation by oxygen sensors, angiogenesis pathway, stem cell master regulators, inflammasomes, and tissue hypo-/hypermethylation indexes; (2) NR sequence mutations are associated with increased risks for development of cancers and metabolic, cardiovascular, and autoimmune diseases; (3) NRs have less tendency to be upregulated than downregulated in cancers, and autoimmune and metabolic diseases, which may be regulated by inflammation pathways and mitochondrial energy enzymes; and (4) the innate immune sensor inflammasome/caspase-1 pathway regulates the expression of most NRs. Based on our findings, we propose a new paradigm that most nuclear receptors are anti-inflammatory homeostasis-associated molecular pattern receptors (HAMPRs). Our results have provided a novel insight on NRs as therapeutic targets in metabolic diseases, inflammations, and malignancies.
datePublished:2017-10-24T00:00:00Z
dateModified:2017-10-24T00:00:00Z
pageStart:1
pageEnd:41
license:http://creativecommons.org/publicdomain/zero/1.0/
sameAs:https://doi.org/10.1186/s13045-017-0526-8
keywords:
Nuclear receptors (NRs)
Homeostasis-associated molecular pattern receptors
Atherosclerosis
Metabolic disease
Cardiovascular disease
Oncology
Hematology
Cancer Research
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig1_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig2_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig3_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig4_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig5_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig6_HTML.gif
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13045-017-0526-8/MediaObjects/13045_2017_526_Fig7_HTML.gif
isPartOf:
name:Journal of Hematology & Oncology
issn:
1756-8722
volumeNumber:10
type:
Periodical
PublicationVolume
publisher:
name:BioMed Central
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Luqiao Wang
affiliation:
name:The Second Affiliated Hospital of Nanchang University
address:
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:The First Affiliated Hospital of Kunming Medical University
address:
name:Department of Cardiovascular Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, China
type:PostalAddress
type:Organization
type:Person
name:Gayani Nanayakkara
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Qian Yang
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Xijing Hospital and Fourth Military Medical University
address:
name:Department of Ultrasound, Xijing Hospital and Fourth Military Medical University, Xi’an, China
type:PostalAddress
type:Organization
type:Person
name:Hongmei Tan
affiliation:
name:Sun Yat-sen University
address:
name:Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
type:PostalAddress
type:Organization
type:Person
name:Charles Drummer
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Yu Sun
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Ying Shao
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Hangfei Fu
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Ramon Cueto
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Huimin Shan
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Teodoro Bottiglieri
affiliation:
name:Baylor Research Institute
address:
name:Institute of Metabolic Disease, Baylor Research Institute, Dallas, USA
type:PostalAddress
type:Organization
type:Person
name:Ya-feng Li
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Candice Johnson
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:William Y. Yang
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Fan Yang
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Yanjie Xu
affiliation:
name:The Second Affiliated Hospital of Nanchang University
address:
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
type:PostalAddress
type:Organization
type:Person
name:Hang Xi
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Weiqing Liu
affiliation:
name:The First Affiliated Hospital of Kunming Medical University
address:
name:Department of Cardiovascular Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, China
type:PostalAddress
type:Organization
type:Person
name:Jun Yu
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Eric T. Choi
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Department of Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Xiaoshu Cheng
affiliation:
name:The Second Affiliated Hospital of Nanchang University
address:
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Hong Wang
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
type:Person
name:Xiaofeng Yang
url:http://orcid.org/0000-0002-6854-6195
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:1
["Periodical","PublicationVolume"]:
name:Journal of Hematology & Oncology
issn:
1756-8722
volumeNumber:10
Organization:
name:BioMed Central
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:The Second Affiliated Hospital of Nanchang University
address:
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:The First Affiliated Hospital of Kunming Medical University
address:
name:Department of Cardiovascular Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, China
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Xijing Hospital and Fourth Military Medical University
address:
name:Department of Ultrasound, Xijing Hospital and Fourth Military Medical University, Xi’an, China
type:PostalAddress
name:Sun Yat-sen University
address:
name:Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Baylor Research Institute
address:
name:Institute of Metabolic Disease, Baylor Research Institute, Dallas, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:The Second Affiliated Hospital of Nanchang University
address:
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:The First Affiliated Hospital of Kunming Medical University
address:
name:Department of Cardiovascular Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, China
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Department of Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:The Second Affiliated Hospital of Nanchang University
address:
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
name:Lewis Katz School of Medicine at Temple University
address:
name:Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Luqiao Wang
affiliation:
name:The Second Affiliated Hospital of Nanchang University
address:
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:The First Affiliated Hospital of Kunming Medical University
address:
name:Department of Cardiovascular Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, China
type:PostalAddress
type:Organization
name:Gayani Nanayakkara
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Qian Yang
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Xijing Hospital and Fourth Military Medical University
address:
name:Department of Ultrasound, Xijing Hospital and Fourth Military Medical University, Xi’an, China
type:PostalAddress
type:Organization
name:Hongmei Tan
affiliation:
name:Sun Yat-sen University
address:
name:Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
type:PostalAddress
type:Organization
name:Charles Drummer
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Yu Sun
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Ying Shao
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Hangfei Fu
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Ramon Cueto
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Huimin Shan
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Teodoro Bottiglieri
affiliation:
name:Baylor Research Institute
address:
name:Institute of Metabolic Disease, Baylor Research Institute, Dallas, USA
type:PostalAddress
type:Organization
name:Ya-feng Li
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Candice Johnson
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:William Y. Yang
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Fan Yang
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Yanjie Xu
affiliation:
name:The Second Affiliated Hospital of Nanchang University
address:
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
type:PostalAddress
type:Organization
name:Hang Xi
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Weiqing Liu
affiliation:
name:The First Affiliated Hospital of Kunming Medical University
address:
name:Department of Cardiovascular Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, China
type:PostalAddress
type:Organization
name:Jun Yu
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Eric T. Choi
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Department of Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Xiaoshu Cheng
affiliation:
name:The Second Affiliated Hospital of Nanchang University
address:
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
type:PostalAddress
type:Organization
email:[email protected]
name:Hong Wang
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Xiaofeng Yang
url:http://orcid.org/0000-0002-6854-6195
affiliation:
name:Lewis Katz School of Medicine at Temple University
address:
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
name:Lewis Katz School of Medicine at Temple University
address:
name:Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Department of Cardiovascular Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, China
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Department of Ultrasound, Xijing Hospital and Fourth Military Medical University, Xi’an, China
name:Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Institute of Metabolic Disease, Baylor Research Institute, Dallas, USA
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Department of Cardiovascular Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, China
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Department of Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Center for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Centers for Cardiovascular Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
name:Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, USA
External Links {🔗}(21)
- How much income does https://www.biomedcentral.com/privacy-statement have?
- How much revenue does https://www.biomedcentral.com generate?
- How much does https://www.biomedcentral.com/journals generate monthly?
- How much does https://www.biomedcentral.com/getpublished earn?
- What are the earnings of https://www.biomedcentral.com/about?
- How much income is https://www.biomedcentral.com/account earning monthly?
- What's the profit of https://submission.nature.com/new-submission/13045/3?
- How much revenue does https://blogs.biomedcentral.com/ generate?
- How much money does https://www.biomedcentral.com/login generate?
- How much money does https://authorservices.springernature.com/go/sn/?utm_source=Website&utm_medium=BMC&utm_campaign=SNAS+Referrals+2022&utm_id=ref2022 generate?
- How much money does https://www.biomedcentral.com/about/policies generate?
- What is the earnings of https://www.biomedcentral.com/accessibility?
- What's the financial outcome of https://www.biomedcentral.com/about/press-centre?
- https://support.biomedcentral.com/support/home income
- How much income is https://biomedcentral.typeform.com/to/VLXboo earning monthly?
- Learn how profitable https://www.biomedcentral.com/about/jobs is on a monthly basis
- What's the profit of http://www.weibo.com/biomedcentral?
- Discover the revenue of https://www.biomedcentral.com/terms-and-conditions
- What's the monthly money flow for https://www.springernature.com/ccpa?
- What's the revenue for https://www.biomedcentral.com/cookies?
- What's the revenue for https://www.springernature.com?
Analytics and Tracking {📊}
- Google Tag Manager
Libraries {📚}
- Prism.js