
DOI . ORG {
}
Title[redir]:
Cell-based HTS identifies a chemical chaperone for preventing ER protein aggregation and proteotoxicity | eLife
Description:
Cell-based high-throughput screening identifies IBT21 as a chemical chaperone, that inhibits ER protein aggregation and prevents the cell death caused by a proteotoxin, the aggregation-prone prion protein.
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Keywords {π}
figure, ibt, protein, proteins, chemical, supplement, stress, download, cell, cells, google, scholar, upr, japan, data, pubmed, chaperones, asset, medical, tokushima, compounds, institute, research, source, university, sciences, molecular, dataset, chaperone, aggregation, unfolded, usa, open, competing, interests, tokyo, misfolded, prion, activity, group, response, effects, reporter, atf, presence, analysis, disease, target, inhibition, activation,
Topics {βοΈ}
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Schema {πΊοΈ}
ScholarlyArticle:
context:https://schema.org
mainEntityOfPage:
type:WebPage
id:https://elifesciences.org/articles/43302
headline:Cell-based HTS identifies a chemical chaperone for preventing ER protein aggregation and proteotoxicity
datePublished:2019-12-17
author:
type:Person
name:Keisuke Kitakaze
type:Person
name:Shusuke Taniuchi
type:Person
name:Eri Kawano
type:Person
name:Yoshimasa Hamada
type:Person
name:Masato Miyake
type:Person
name:Miho Oyadomari
type:Person
name:Hirotatsu Kojima
type:Person
name:Hidetaka Kosako
type:Person
name:Tomoko Kuribara
type:Person
name:Suguru Yoshida
type:Person
name:Takamitsu Hosoya
type:Person
name:Seiichi Oyadomari
publisher:
type:Organization
name:eLife Sciences Publications, Ltd
logo:
type:ImageObject
url:https://elifesciences.org/assets/patterns/img/patterns/organisms/[email protected]
keywords:
ER stress
chemical chaperone
proteotoxicity
about:
Biochemistry and Chemical Biology
Cell Biology
description:Cell-based high-throughput screening identifies IBT21 as a chemical chaperone, that inhibits ER protein aggregation and prevents the cell death caused by a proteotoxin, the aggregation-prone prion protein.
isPartOf:
type:Periodical
name:eLife
issn:2050-084X
WebPage:
id:https://elifesciences.org/articles/43302
Person:
name:Keisuke Kitakaze
name:Shusuke Taniuchi
name:Eri Kawano
name:Yoshimasa Hamada
name:Masato Miyake
name:Miho Oyadomari
name:Hirotatsu Kojima
name:Hidetaka Kosako
name:Tomoko Kuribara
name:Suguru Yoshida
name:Takamitsu Hosoya
name:Seiichi Oyadomari
Organization:
name:eLife Sciences Publications, Ltd
logo:
type:ImageObject
url:https://elifesciences.org/assets/patterns/img/patterns/organisms/[email protected]
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Periodical:
name:eLife
issn:2050-084X
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