
DOI . ORG {
}
Title[redir]:
Angiopoietin receptor Tie2 is required for vein specification and maintenance via regulating COUP-TFII | eLife
Description:
Analyses with genetically engineered mouse models in combination with biochemical approaches reveal a crucial role of the receptor tyrosine kinase Tie2 mediated signals in venogenesis via an Akt mediated regulation of COUP-TFII protein stabilization.
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Keywords {π}
tie, figure, mice, analysis, competing, interests, university, venous, tek, couptfii, data, control, china, google, scholar, article, vascular, center, pubmed, tekiucko, deletion, hematology, development, soochow, blood, asset, retinal, cell, mutant, cells, suzhou, veins, interpretation, protein, contribution, drafting, revising, download, supplement, declared, httpsdoiorgelife, arterial, open, endothelial, formation, gene, vein, signaling, skin, akt,
Topics {βοΈ}
methods references article rabbit monoclonal anti-phospho-akt473 quantitative real-time rtβpcr rabbit polyclonal anti-phospho-p56dok-2 real-time rt-pcr revealed mouse monoclonal anti-coup-tfii angiopoietin-1-dependent cell migration gou young koh ras-erk pathway downstream rabbit polyclonal anti-p56dok-2 real-time rt-pcr tekflox/β/ubc-creert2 neonatal mice rabbit polyclonal anti-erk1/2 rabbit polyclonal anti-akt cell-autonomous effect resulting tekflox/+/cdh5-creert2 littermate mice goat anti-mouse tie2 regulate coup-tfii expression coup-tfii protein stability arita adams max-planck-institute goat anti-mouse dll4 goat anti-mouse ephb4 rat anti-mouse pecam-1 inhibit raf1-erk1/2 signaling stimulate tie2/akt pathway coup-tfii protein level long-term postnatal attenuation protein-tyrosine kinases genes coup-tfii mrna level de boer ischemia-induced retinal neovascularization fluorochrome-conjugated secondary antibodies wnt/Ξ²-catenin endothelial cell-cell mouse genomic sequences abnormal arterial-venous alignment myocardium-derived angiopoietin-1 mediates angiopoietin signaling guoqiang xu college ligand-independent tie2 activation analyzed coup-tfii level angiopoietin receptor tie2 receptor tyrosine kinase endothelial cell migration blood vessel growth gene targeting leads press resources xml mouse retinal vascularization regulate venous identity
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id:https://elifesciences.org/articles/21032
headline:Angiopoietin receptor Tie2 is required for vein specification and maintenance via regulating COUP-TFII
datePublished:2016-12-22
author:
type:Person
name:Man Chu
type:Person
name:Taotao Li
type:Person
name:Bin Shen
type:Person
name:Xudong Cao
type:Person
name:Haoyu Zhong
type:Person
name:Luqing Zhang
type:Person
name:Fei Zhou
type:Person
name:Wenjuan Ma
type:Person
name:Haijuan Jiang
type:Person
name:Pancheng Xie
type:Person
name:Zhengzheng Liu
type:Person
name:Ningzheng Dong
type:Person
name:Ying Xu
type:Person
name:Yun Zhao
type:Person
name:Guoqiang Xu
type:Person
name:Peirong Lu
type:Person
name:Jincai Luo
type:Person
name:Qingyu Wu
type:Person
name:Kari Alitalo
type:Person
name:Gou Young Koh
type:Person
name:Ralf H Adams
type:Person
name:Yulong He
publisher:
type:Organization
name:eLife Sciences Publications, Ltd
logo:
type:ImageObject
url:https://elifesciences.org/assets/patterns/img/patterns/organisms/[email protected]
keywords:
Tie2
COUP-TFII
vein specification
about:
Developmental Biology
description:Analyses with genetically engineered mouse models in combination with biochemical approaches reveal a crucial role of the receptor tyrosine kinase Tie2 mediated signals in venogenesis via an Akt mediated regulation of COUP-TFII protein stabilization.
isPartOf:
type:Periodical
name:eLife
issn:2050-084X
WebPage:
id:https://elifesciences.org/articles/21032
Person:
name:Man Chu
name:Taotao Li
name:Bin Shen
name:Xudong Cao
name:Haoyu Zhong
name:Luqing Zhang
name:Fei Zhou
name:Wenjuan Ma
name:Haijuan Jiang
name:Pancheng Xie
name:Zhengzheng Liu
name:Ningzheng Dong
name:Ying Xu
name:Yun Zhao
name:Guoqiang Xu
name:Peirong Lu
name:Jincai Luo
name:Qingyu Wu
name:Kari Alitalo
name:Gou Young Koh
name:Ralf H Adams
name:Yulong He
Organization:
name:eLife Sciences Publications, Ltd
logo:
type:ImageObject
url:https://elifesciences.org/assets/patterns/img/patterns/organisms/[email protected]
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issn:2050-084X
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